MP
Pittet, Mikaël
Affiliation entities
Research groups
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Deep profiling of gene expression across 18 human cancers | Nature biomedical engineering | 2025 | 2 | 4 | |||
| Mitochondrial control of macrophage polarity in tumors | Immunity | 2025 | 3 | 0 | |||
| Targeting cancer-associated fibroblasts for real-time intraoperative tumor identification with a spray-on fluorescent probe | Science advances | 2025 | 1 | 0 | |||
| From complexity to consensus : A roadmap for neutrophil classification | Immunity | 2025 | 2 | 0 | |||
| Combination CXCR4 and PD-1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma | Cancer immunology research | 2025 | 2 | 0 | |||
| Convergent inducers and effectors of T cell paralysis in the tumour microenvironment | Nature reviews. Cancer | 2025 | 39 | 0 | |||
| IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity | Journal for immunotherapy of cancer | 2025 | 1 | 0 | |||
| Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype | Advanced science | 2024 | 215 | 81 | |||
| Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy | Cell | 2024 | 940 | 232 | |||
| Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanoma | Science immunology | 2024 | 262 | 0 | |||
| GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model | Frontiers in immunology | 2024 | 178 | 49 | |||
| Unveiling the antitumor function of ID3 in liver macrophages | Nature immunology | 2024 | 135 | 60 | |||
| Dendritic cells as shepherds of T cell immunity in cancer | Immunity | 2023 | 62 | 16 | |||
| A neutrophil response linked to tumor control in immunotherapy | Cell | 2023 | 64 | 30 | |||
| Clonal expansion of intra-epithelial T cells in breast cancer revealed by spatial transcriptomics | International journal of cancer | 2023 | 503 | 76 | |||
| Dendritic cells direct circadian anti-tumour immune responses | Nature | 2023 | 769 | 185 | |||
| CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers | Science | 2023 | 782 | 2 | |||
| Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer | Clinical cancer research | 2023 | 55 | 31 | |||
| Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity | Journal for immunotherapy of cancer | 2023 | 40 | 16 | |||
| IPCI et radiothérapie : main dans la main contre le cancer | Revue médicale suisse | 2022 | 83 | 74 | |||
| TNIK inhibition has dual synergistic effects on tumor and associated immune cells | Advanced biology | 2022 | 143 | 98 | |||
| Clinical relevance of tumour-associated macrophages | Nature reviews. Clinical oncology | 2022 | 552 | 1 | |||
| Renin–angiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors | European journal of cancer | 2022 | 3 | 10 | |||
| Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNg-Secreting Lymphocytes and IL12-Producing Dendritic Cells | Cancer immunology research | 2022 | 195 | 46 | |||
| Abstract C043: Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer | AACR Special Conference | 2022 | 208 | 5 | |||
| Neutrophil phenotypes and functions in cancer: a consensus statement | The Journal of experimental medicine | 2022 | 190 | 43 | |||
| Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes | Nature biotechnology | 2022 | 256 | 430 | |||
| Metacells untangle large and complex single-cell transcriptome networks | BMC bioinformatics | 2022 | 470 | 128 | |||
| The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy | Cancer cell | 2022 | 118 | 0 | |||
| Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy | Proceedings of the National Academy of Sciences of the United States of America | 2021 | 113 | 100 | |||
| Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy | Science Immunology | 2021 | 458 | 940 | |||
| How are methodological developments enabling insights into cell behavior in cellular communities ? | Cell systems | 2021 | 103 | 76 | |||
| Versatile neutrophil functions in cancer | Seminars in immunology | 2021 | 88 | 98 | |||
| Low dose radiotherapy reverses tumor immune desertification and resistance to immunotherapy | Cancer Discovery | 2021 | 354 | 236 | |||
| Myeloid cells are enriched in tonsillar crypts, providing insight into the viral tropism of human papillomavirus | The American journal of pathology | 2021 | 202 | 145 | |||
| CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment | Cell | 2021 | 543 | 2 | |||
| Rapid serial immunoprofiling of the tumor immune microenvironment by fine needle sampling | Clinical Cancer Research | 2021 | 250 | 2 | |||
| Diagnostic challenges and successful organ-preserving therapy in a case of secretory carcinoma of minor salivary glands | Cancer Reports | 2021 | 193 | 125 | |||
| Innate immune cells in the tumor microenvironment | Cancer Cell | 2021 | 386 | 7 | |||
| Tumor-infiltrating dendritic cell states are conserved across solid human cancers | Journal of Experimental Medicine | 2021 | 293 | 295 | |||
| COVID-19 diagnostics in context | Science Translational Medicine | 2020 | 224 | 671 | |||
| The chemical biology of IL-12 production via the non-canonical NFkB pathway | RSC chemical biology | 2020 | 80 | 152 | |||
| A durable murine model of spleen transplantation with arterial and venous anastomoses | Scientific reports | 2020 | 77 | 26 | |||
| Myeloid cell-targeted nanocarriers efficiently inhibit cellular inhibitor of apoptosis for cancer immunotherapy | Cell chemical biology | 2020 | 84 | 66 | |||
| Phase II trial of IL-12 plasmid transfection and PD-1 blockade in immunologically quiescent melanoma | Clinical Cancer Research | 2020 | 218 | 0 | |||
| Durable and controlled depletion of neutrophils in mice | Nature Communications | 2020 | 321 | 418 | |||
| Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils | Cell Reports | 2020 | 212 | 182 | |||
| New technology on the horizon: Fast analytical screening technique FNA (FAST-FNA) enables rapid, multiplex biomarker analysis in head and neck cancers | Cancer Cytopathology | 2020 | 172 | 1 | |||
| The expanding landscape of inflammatory cells affecting cancer therapy | Nature Biomedical Engineering | 2020 | 217 | 322 | |||
| Single extracellular vesicle protein analysis using immuno-droplet digital polymerase chain reaction amplification | Advanced Biosystems | 2020 | 187 | 121 | |||
| Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy | Theranostics | 2019 | 2 | 10 | |||
| Natural killer cells limit the clearance of senescent lung adenocarcinoma cells | Oncogenesis | 2019 | 1 | 0 | |||
| Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke | Circulation research | 2019 | 5 | 9 | |||
| Tissue-specific macrophage responses to remote injury impact the outcome of subsequent local immune challenge | Immunity | 2019 | 361 | 476 | |||
| LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects | Cell Stress | 2019 | 222 | 114 | |||
| Crizotinib-induced immunogenic cell death in non-small cell lung cancer | Nature Communications | 2019 | 219 | 145 | |||
| Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species | Immunity | 2019 | 321 | 550 | |||
| Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using 64Cu-Labeled Macrin | ACS nano | 2018 | 2 | 1 | |||
| Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system | Mucosal immunology | 2018 | 3 | 1 | |||
| Understanding the tumor immune microenvironment (TIME) for effective therapy | Nature Medicine | 2018 | 242 | 1 | |||
| Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages | Theranostics | 2018 | 1 | 1 | |||
| TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy | Nature Biomedical Engineering | 2018 | 224 | 0 | |||
| Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells | JCI insight | 2018 | 1 | 0 | |||
| Recording the wild lives of immune cells | Science Immunology | 2018 | 174 | 0 | |||
| Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 | Immunity | 2018 | 327 | 797 | |||
| Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3d organ imaging | Nature Communications | 2017 | 187 | 111 | |||
| Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts | Science Translational Medicine | 2017 | 171 | 0 | |||
| In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy | Science Translational Medicine | 2017 | 234 | 2 | |||
| Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils | Science | 2017 | 234 | 0 | |||
| Tumor microenvironment: no effector T cells without dendritic cells | Cancer Cell | 2017 | 176 | 160 | |||
| Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease | Chemical communications | 2017 | 2 | 4 | |||
| Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway | Proceedings of the National Academy of Sciences | 2016 | 191 | 0 | |||
| Neutrophils suppress intraluminal NK cell-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells | Cancer Discovery | 2016 | 228 | 108 | |||
| SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions | Science | 2016 | 188 | 0 | |||
| Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy | Immunity | 2016 | 303 | 0 | |||
| The role of myeloid cells in cancer therapies | Nature Reviews Cancer | 2016 | 177 | 0 | |||
| Gal3 links inflammation and insulin resistance | Cell Metabolism | 2016 | 175 | 65 | |||
| PF4 promotes platelet production and lung cancer growth | Cell Reports | 2016 | 215 | 195 | |||
| Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle | Science Translational Medicine | 2015 | 202 | 0 | |||
| Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor | PloS one | 2015 | 1 | 2 | |||
| Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug | Nature communications | 2015 | 1 | 0 | |||
| Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer | Oncogene | 2015 | 1 | 0 | |||
| Common TLR5 mutations control cancer progression | Cancer Cell | 2015 | 168 | 0 | |||
| Gut microbiome and anticancer immune response : really hot Sh*t! | Cell death and differentiation | 2015 | 1 | 2 | |||
| ER stress in dendritic cells promotes cancer | Cell | 2015 | 176 | 0 | |||
| Harnessing the intestinal microbiome for optimal therapeutic immunomodulation | Cancer Research | 2014 | 226 | 0 | |||
| Imaging macrophages with nanoparticles | Nature Materials | 2014 | 176 | 0 | |||
| The journey from stem cell to macrophage | Annals of the New York Academy of Sciences | 2014 | 1 | 0 | |||
| Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis1 | Biology of reproduction | 2014 | 1 | 2 | |||
| Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy | Nature medicine | 2014 | 1 | 0 | |||
| Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis | Andrology | 2014 | 3 | 9 | |||
| Therapeutically reeducating macrophages to treat GBM | Nature medicine | 2013 | 1 | 0 | |||
| Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer | Oncoimmunology | 2013 | 1 | 0 | |||
| The Spleen in Local and Systemic Regulation of Immunity | Immunity | 2013 | 3 | 4 | |||
| Remote control of macrophage production by cancer | Oncoimmunology | 2013 | 1 | 1 | |||
| Molecular Pathways : Tumor-Derived Microvesicles and Their Interactions with Immune Cells In Vivo | Clinical cancer research | 2013 | 2 | 2 | |||
| MicroRNA-mediated control of macrophages and its implications for cancer | Trends in immunology | 2013 | 4 | 5 | |||
| Angiotensin II Drives the Production of Tumor-Promoting Macrophages | Immunity | 2013 | 2 | 0 | |||
| The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide | Science | 2013 | 1 | 0 | |||
| Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors | Journal of innate immunity | 2012 | 3 | 5 | |||
| Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb | Cell reports | 2012 | 1 | 1 | |||
| Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium | PLoS biology | 2012 | 1 | 2 | |||
| Extramedullary Hematopoiesis Generates Ly-6Chigh Monocytes That Infiltrate Atherosclerotic Lesions | Circulation | 2012 | 1 | 1 | |||
| Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis | The journal of experimental medicine | 2012 | 1 | 1 | |||
| Origins of tumor-associated macrophages and neutrophils | Proceedings of the National Academy of Sciences of the United States of America | 2012 | 1 | 0 | |||
| Myocardial infarction accelerates atherosclerosis | Nature | 2012 | 1 | 1 | |||
| Innate Response Activator B Cells Protect Against Microbial Sepsis | Science | 2012 | 2 | 1 | |||
| PET/MRI of Inflammation in Myocardial Infarction | Journal of the American College of Cardiology | 2012 | 2 | 1 | |||
| Intravital Imaging | Cell | 2011 | 1 | 1 | |||
| In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation | Nature medicine | 2011 | 2 | 1 | |||
| Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography–Computed Tomography | Arteriosclerosis, thrombosis, and vascular biology | 2011 | 6 | 6 | |||
| 89Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging | Bioconjugate chemistry | 2011 | 4 | 4 | |||
| A dense network of dendritic cells populates the murine epididymis | Reproduction | 2011 | 6 | 9 | |||
| Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages | The Journal of immunology | 2011 | 4 | 3 | |||
| Monocytes link atherosclerosis and cancer | European Journal of Immunology | 2011 | 1 | 0 | |||
| Therapeutic siRNA silencing in inflammatory monocytes in mice | Nature biotechnology | 2011 | 1 | 0 | |||
| Self-assembled magnetic filter for highly efficient immunomagnetic separation | Lab on a chip | 2011 | 1 | 1 | |||
| Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice | The Journal of clinical investigation | 2010 | 2 | 4 | |||
| Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis | Journal of the American College of Cardiology | 2010 | 1 | 1 | |||
| Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography | Optics letters | 2010 | 3 | 3 | |||
| Hybrid PET-optical imaging using targeted probes | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2 | 4 | |||
| Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction | Circulation research | 2010 | 1 | 0 | |||
| Monocytes : Protagonists of Infarct Inflammation and Repair After Myocardial Infarction | Circulation | 2010 | 3 | 3 | |||
| Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis | Arteriosclerosis, thrombosis, and vascular biology | 2009 | 1 | 1 | |||
| Behavior of immune players in the tumor microenvironment | Current opinion in oncology | 2009 | 5 | 5 | |||
| Monocyte Subset Dynamics in Human Atherosclerosis Can Be Profiled with Magnetic Nano-Sensors | PloS one | 2009 | 1 | 2 | |||
| Behavior of Endogenous Tumor-Associated Macrophages Assessed In Vivo Using a Functionalized Nanoparticle | Neoplasia | 2009 | 1 | 0 | |||
| Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors | Arteriosclerosis, thrombosis, and vascular biology | 2009 | 2 | 0 | |||
| Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites | Science | 2009 | 1 | 0 | |||
| Diversity of Denizens of the Atherosclerotic Plaque | Circulation | 2008 | 2 | 0 | |||
| Perturbational profiling of nanomaterial biologic activity | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 1 | 2 | |||
| Imaging in the era of molecular oncology | Nature | 2008 | 3 | 2 | |||
| Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation | The Journal of clinical investigation | 2008 | 1 | 0 | |||
| Regulation of T‐cell migration and effector functions : insights from in vivo imaging studies | Immunological reviews | 2008 | 1 | 0 | |||
| Direct Presentation of Antigen by Lymph Node Stromal Cells Protects Against CD8 T-Cell-Mediated Intestinal Autoimmunity | Gastroenterology | 2008 | 2 | 0 | |||
| Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes | The Journal of immunology | 2007 | 1 | 0 | |||
| In vivo imaging of T cell delivery to tumors after adoptive transfer therapy | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 6 | 3 | |||
| A Near-Infrared Cell Tracker Reagent for Multiscopic In Vivo Imaging and Quantification of Leukocyte Immune Responses | PloS one | 2007 | 1 | 1 | |||
| Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata | The Journal of clinical investigation | 2007 | 1 | 1 | |||
| Dual Channel Optical Tomographic Imaging of Leukocyte Recruitment and Protease Activity in the Healing Myocardial Infarct | Circulation research | 2007 | 2 | 0 | |||
| The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions | The journal of experimental medicine | 2007 | 1 | 0 | |||
| Improved in Vivo Whole-Animal Detection Limits of Green Fluorescent Protein–Expressing Tumor Lines by Spectral Fluorescence Imaging | Molecular imaging | 2007 | 1 | 1 | |||
| Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance | Cancer research | 2004 | 118 | 0 |
