Pittet, MikaÃ«l

Title	Published in	Year	Views	Downloads
Perioperative myeloid cell remodeling shapes CAR-T cell efficacy in glioblastoma	Nature communications	2026	32	21
Positioning and reversible suppression of CCR7⁺ dendritic cells in perivascular tumor niches shape cancer immunity	Immunity	2026	64	61
Deep profiling of gene expression across 18 human cancers	Nature biomedical engineering	2025	61	265
Mitochondrial control of macrophage polarity in tumors	Immunity	2025	80	0
Targeting cancer-associated fibroblasts for real-time intraoperative tumor identification with a spray-on fluorescent probe	Science advances	2025	48	31
From complexity to consensus : A roadmap for neutrophil classification	Immunity	2025	26	0
Combination CXCR4 and PD-1 Blockade Enhances Intratumoral Dendritic Cell Activation and Immune Responses Against Hepatocellular Carcinoma	Cancer immunology research	2025	52	29
Convergent inducers and effectors of T cell paralysis in the tumour microenvironment	Nature reviews. Cancer	2025	75	0
IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity	Journal for immunotherapy of cancer	2025	30	68
Pharmacological Polarization of Tumor-Associated Macrophages Toward a CXCL9 Antitumor Phenotype	Advanced science	2024	247	322
Circadian tumor infiltration and function of CD8+ T cells dictate immunotherapy efficacy	Cell	2024	1,025	651
Response to tumor-infiltrating lymphocyte adoptive therapy is associated with preexisting CD8+ T-myeloid cell networks in melanoma	Science immunology	2024	301	0
GSDMD is associated with survival in human breast cancer but does not impact anti-tumor immunity in a mouse breast cancer model	Frontiers in immunology	2024	202	82
Unveiling the antitumor function of ID3 in liver macrophages	Nature immunology	2024	162	106
Dendritic cells as shepherds of T cell immunity in cancer	Immunity	2023	78	126
A neutrophil response linked to tumor control in immunotherapy	Cell	2023	98	163
Clonal expansion of intra-epithelial T cells in breast cancer revealed by spatial transcriptomics	International journal of cancer	2023	521	109
Dendritic cells direct circadian anti-tumour immune responses	Nature	2023	812	238
CXCL9:SPP1 macrophage polarity identifies a network of cellular programs that control human cancers	Science	2023	812	2
Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer	Clinical cancer research	2023	67	114
Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity	Journal for immunotherapy of cancer	2023	53	32
IPCI et radiothérapie : main dans la main contre le cancer	Revue médicale suisse	2022	96	140
TNIK inhibition has dual synergistic effects on tumor and associated immune cells	Advanced biology	2022	154	217
Clinical relevance of tumour-associated macrophages	Nature reviews. Clinical oncology	2022	573	1
Renin–angiotensin–aldosterone system inhibitors and survival in patients with hypertension treated with immune checkpoint inhibitors	European journal of cancer	2022	19	211
Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNg-Secreting Lymphocytes and IL12-Producing Dendritic Cells	Cancer immunology research	2022	205	78
Abstract C043: Addition of losartan to FOLFORINOX and chemoradiation downregulates pro-invasion and immunosuppression-associated genes in locally advanced pancreatic cancer	AACR Special Conference	2022	223	5
Neutrophil phenotypes and functions in cancer: a consensus statement	The Journal of experimental medicine	2022	204	88
Spatiotemporal multiplexed immunofluorescence imaging of living cells and tissues with bioorthogonal cycling of fluorescent probes	Nature biotechnology	2022	272	556
Metacells untangle large and complex single-cell transcriptome networks	BMC bioinformatics	2022	484	159
The local microenvironment matters in preclinical basic and translational studies of cancer immunology and immunotherapy	Cancer cell	2022	135	0
Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy	Proceedings of the National Academy of Sciences of the United States of America	2021	122	154
Resident Kupffer cells and neutrophils drive liver toxicity in cancer immunotherapy	Science Immunology	2021	479	1,033
How are methodological developments enabling insights into cell behavior in cellular communities ?	Cell systems	2021	116	95
Versatile neutrophil functions in cancer	Seminars in immunology	2021	100	148
Low dose radiotherapy reverses tumor immune desertification and resistance to immunotherapy	Cancer Discovery	2021	368	550
Myeloid cells are enriched in tonsillar crypts, providing insight into the viral tropism of human papillomavirus	The American journal of pathology	2021	213	301
CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment	Cell	2021	565	2
Rapid serial immunoprofiling of the tumor immune microenvironment by fine needle sampling	Clinical Cancer Research	2021	262	2
Diagnostic challenges and successful organ-preserving therapy in a case of secretory carcinoma of minor salivary glands	Cancer Reports	2021	203	249
Innate immune cells in the tumor microenvironment	Cancer Cell	2021	400	7
Tumor-infiltrating dendritic cell states are conserved across solid human cancers	Journal of Experimental Medicine	2021	305	580
COVID-19 diagnostics in context	Science Translational Medicine	2020	236	1,716
The chemical biology of IL-12 production via the non-canonical NFkB pathway	RSC chemical biology	2020	90	233
A durable murine model of spleen transplantation with arterial and venous anastomoses	Scientific reports	2020	93	73
Myeloid cell-targeted nanocarriers efficiently inhibit cellular inhibitor of apoptosis for cancer immunotherapy	Cell chemical biology	2020	94	181
Phase II trial of IL-12 plasmid transfection and PD-1 blockade in immunologically quiescent melanoma	Clinical Cancer Research	2020	234	0
Durable and controlled depletion of neutrophils in mice	Nature Communications	2020	335	1,232
Tumor-promoting Ly-6G+ SiglecFhigh cells are mature and long-lived neutrophils	Cell Reports	2020	227	247
New technology on the horizon: Fast analytical screening technique FNA (FAST-FNA) enables rapid, multiplex biomarker analysis in head and neck cancers	Cancer Cytopathology	2020	191	1
The expanding landscape of inflammatory cells affecting cancer therapy	Nature Biomedical Engineering	2020	228	510
Single extracellular vesicle protein analysis using immuno-droplet digital polymerase chain reaction amplification	Advanced Biosystems	2020	200	237
Development of Adamantane-Conjugated TLR7/8 Agonists for Supramolecular Delivery and Cancer Immunotherapy	Theranostics	2019	20	610
Natural killer cells limit the clearance of senescent lung adenocarcinoma cells	Oncogenesis	2019	20	52
Glucocorticoids Regulate Bone Marrow B Lymphopoiesis After Stroke	Circulation research	2019	17	229
Tissue-specific macrophage responses to remote injury impact the outcome of subsequent local immune challenge	Immunity	2019	375	769
LTX-315 sequentially promotes lymphocyte-independent and lymphocyte-dependent antitumor effects	Cell Stress	2019	233	205
Crizotinib-induced immunogenic cell death in non-small cell lung cancer	Nature Communications	2019	231	185
Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species	Immunity	2019	342	789
Quantitative Imaging of Tumor-Associated Macrophages and Their Response to Therapy Using ⁶⁴Cu-Labeled Macrin	ACS nano	2018	15	28
Intestinal epithelial cell-specific RARα depletion results in aberrant epithelial cell homeostasis and underdeveloped immune system	Mucosal immunology	2018	20	61
Understanding the tumor immune microenvironment (TIME) for effective therapy	Nature Medicine	2018	253	1
Arg1 expression defines immunosuppressive subsets of tumor-associated macrophages	Theranostics	2018	16	22
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy	Nature Biomedical Engineering	2018	237	0
Age-related tumor growth in mice is related to integrin α 4 in CD8+ T cells	JCI insight	2018	15	17
Recording the wild lives of immune cells	Science Immunology	2018	185	0
Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12	Immunity	2018	347	1,430
Heterogeneity of macrophage infiltration and therapeutic response in lung carcinoma revealed by 3d organ imaging	Nature Communications	2017	202	157
Radiation therapy primes tumors for nanotherapeutic delivery via macrophage-mediated vascular bursts	Science Translational Medicine	2017	181	0
In vivo imaging reveals a tumor-associated macrophage-mediated resistance pathway in anti-PD-1 therapy	Science Translational Medicine	2017	245	2
Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils	Science	2017	245	0
Tumor microenvironment: no effector T cells without dendritic cells	Cancer Cell	2017	189	278
Near infrared imaging of Mer tyrosine kinase (MERTK) using MERi-SiR reveals tumor associated macrophage uptake in metastatic disease	Chemical communications	2017	13	82
Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway	Proceedings of the National Academy of Sciences	2016	205	0
Neutrophils suppress intraluminal NK cell-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells	Cancer Discovery	2016	249	202
SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions	Science	2016	200	0
Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy	Immunity	2016	314	0
The role of myeloid cells in cancer therapies	Nature Reviews Cancer	2016	187	0
Gal3 links inflammation and insulin resistance	Cell Metabolism	2016	185	125
PF4 promotes platelet production and lung cancer growth	Cell Reports	2016	232	297
Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle	Science Translational Medicine	2015	215	0
Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y₁₄ Receptor	PloS one	2015	16	66
Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug	Nature communications	2015	18	32
Immune-dependent antineoplastic effects of cisplatin plus pyridoxine in non-small-cell lung cancer	Oncogene	2015	16	0
Common TLR5 mutations control cancer progression	Cancer Cell	2015	178	0
Gut microbiome and anticancer immune response : really hot Sh*t!	Cell death and differentiation	2015	15	264
ER stress in dendritic cells promotes cancer	Cell	2015	187	0
Harnessing the intestinal microbiome for optimal therapeutic immunomodulation	Cancer Research	2014	236	0
Imaging macrophages with nanoparticles	Nature Materials	2014	187	0
The journey from stem cell to macrophage	Annals of the New York Academy of Sciences	2014	15	539
Epithelial Basal Cells Are Distinct from Dendritic Cells and Macrophages in the Mouse Epididymis1	Biology of reproduction	2014	16	16
Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy	Nature medicine	2014	15	0
Mononuclear phagocytes rapidly clear apoptotic epithelial cells in the proximal epididymis	Andrology	2014	14	40
Therapeutically reeducating macrophages to treat GBM	Nature medicine	2013	16	0
Longitudinal confocal microscopy imaging of solid tumor destruction following adoptive T cell transfer	Oncoimmunology	2013	17	18
The Spleen in Local and Systemic Regulation of Immunity	Immunity	2013	14	42
Remote control of macrophage production by cancer	Oncoimmunology	2013	14	15
Molecular Pathways : Tumor-Derived Microvesicles and Their Interactions with Immune Cells In Vivo	Clinical cancer research	2013	16	113
MicroRNA-mediated control of macrophages and its implications for cancer	Trends in immunology	2013	16	24
Angiotensin II Drives the Production of Tumor-Promoting Macrophages	Immunity	2013	14	23
The Intestinal Microbiota Modulates the Anticancer Immune Effects of Cyclophosphamide	Science	2013	24	98
Regulation of Macrophage and Dendritic Cell Responses by Their Lineage Precursors	Journal of innate immunity	2012	18	249
Regulation of Monocyte Functional Heterogeneity by miR-146a and Relb	Cell reports	2012	15	61
Multi-Scale In Vivo Systems Analysis Reveals the Influence of Immune Cells on TNF-α-Induced Apoptosis in the Intestinal Epithelium	PLoS biology	2012	18	19
Extramedullary Hematopoiesis Generates Ly-6C^high Monocytes That Infiltrate Atherosclerotic Lesions	Circulation	2012	17	57
Rapid monocyte kinetics in acute myocardial infarction are sustained by extramedullary monocytopoiesis	The Journal of experimental medicine	2012	19	34
Origins of tumor-associated macrophages and neutrophils	Proceedings of the National Academy of Sciences of the United States of America	2012	16	109
Myocardial infarction accelerates atherosclerosis	Nature	2012	19	419
Innate Response Activator B Cells Protect Against Microbial Sepsis	Science	2012	17	166
PET/MRI of Inflammation in Myocardial Infarction	Journal of the American College of Cardiology	2012	17	35
Intravital Imaging	Cell	2011	20	239
In vivo detection of Staphylococcus aureus endocarditis by targeting pathogen-specific prothrombin activation	Nature medicine	2011	17	78
Detection of Macrophages in Aortic Aneurysms by Nanoparticle Positron Emission Tomography–Computed Tomography	Arteriosclerosis, thrombosis, and vascular biology	2011	18	76
⁸⁹Zr-Labeled Dextran Nanoparticles Allow in Vivo Macrophage Imaging	Bioconjugate chemistry	2011	18	253
A dense network of dendritic cells populates the murine epididymis	Reproduction	2011	21	98
Dragon (Repulsive Guidance Molecule b) Inhibits IL-6 Expression in Macrophages	The Journal of immunology	2011	16	26
Monocytes link atherosclerosis and cancer	European Journal of Immunology	2011	17	33
Therapeutic siRNA silencing in inflammatory monocytes in mice	Nature biotechnology	2011	14	38
Self-assembled magnetic filter for highly efficient immunomagnetic separation	Lab on a chip	2011	20	42
Myeloperoxidase-rich Ly-6C+ myeloid cells infiltrate allografts and contribute to an imaging signature of organ rejection in mice	The Journal of clinical investigation	2010	14	11
Impaired Infarct Healing in Atherosclerotic Mice With Ly-6ChiMonocytosis	Journal of the American College of Cardiology	2010	14	82
Imaging of molecular probe activity with Born-normalized fluorescence optical projection tomography	Optics letters	2010	17	21
Hybrid PET-optical imaging using targeted probes	Proceedings of the National Academy of Sciences of the United States of America	2010	14	68
Angiotensin-Converting Enzyme Inhibition Prevents the Release of Monocytes From Their Splenic Reservoir in Mice With Myocardial Infarction	Circulation research	2010	16	67
Monocytes : Protagonists of Infarct Inflammation and Repair After Myocardial Infarction	Circulation	2010	14	39
Heterogeneous In Vivo Behavior of Monocyte Subsets in Atherosclerosis	Arteriosclerosis, thrombosis, and vascular biology	2009	17	53
Behavior of immune players in the tumor microenvironment	Current opinion in oncology	2009	18	154
Monocyte Subset Dynamics in Human Atherosclerosis Can Be Profiled with Magnetic Nano-Sensors	PloS one	2009	18	58
Behavior of Endogenous Tumor-Associated Macrophages Assessed In Vivo Using a Functionalized Nanoparticle	Neoplasia	2009	15	17
Hybrid In Vivo FMT-CT Imaging of Protease Activity in Atherosclerosis With Customized Nanosensors	Arteriosclerosis, thrombosis, and vascular biology	2009	17	65
Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites	Science	2009	20	102
Diversity of Denizens of the Atherosclerotic Plaque	Circulation	2008	16	34
Perturbational profiling of nanomaterial biologic activity	Proceedings of the National Academy of Sciences of the United States of America	2008	17	49
Imaging in the era of molecular oncology	Nature	2008	17	58
Real-time assessment of inflammation and treatment response in a mouse model of allergic airway inflammation	The Journal of clinical investigation	2008	20	18
Regulation of T‐cell migration and effector functions : insights from in vivo imaging studies	Immunological reviews	2008	21	0
Direct Presentation of Antigen by Lymph Node Stromal Cells Protects Against CD8 T-Cell-Mediated Intestinal Autoimmunity	Gastroenterology	2008	16	0
Four Functionally Distinct Populations of Human Effector-Memory CD8+ T Lymphocytes	The Journal of immunology	2007	17	0
In vivo imaging of T cell delivery to tumors after adoptive transfer therapy	Proceedings of the National Academy of Sciences of the United States of America	2007	18	74
A Near-Infrared Cell Tracker Reagent for Multiscopic In Vivo Imaging and Quantification of Leukocyte Immune Responses	PloS one	2007	17	44
Ly-6C^hi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata	The Journal of clinical investigation	2007	16	208
Dual Channel Optical Tomographic Imaging of Leukocyte Recruitment and Protease Activity in the Healing Myocardial Infarct	Circulation research	2007	17	31
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions	The Journal of experimental medicine	2007	21	117
Improved in Vivo Whole-Animal Detection Limits of Green Fluorescent Protein–Expressing Tumor Lines by Spectral Fluorescence Imaging	Molecular imaging	2007	18	44
Effector function of human tumor-specific CD8 T cells in melanoma lesions: a state of local functional tolerance	Cancer research	2004	129	0