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Tumor microenvironment: no effector T cells without dendritic cells

Published inCancer Cell, vol. 31, no. 5, p. 614-615
Publication date2017
Abstract

Successful antitumor immunity is thought to require T cell entry into tumors, though mechanisms regulating this process remain unclear. In this issue of Cancer Cell, Spranger et al. indicate that chemokines produced by intratumoral Batf3 dendritic cells are critical for effector T cell recruitment. The findings have implications for immunotherapy.

Keywords
  • Chemokines/immunology
  • Dendritic Cells/immunology
  • Humans
  • Immunotherapy
  • T-Lymphocytes/immunology
  • Tumor Microenvironment/immunology
Affiliation entities Not a UNIGE publication
Citation (ISO format)
PFIRSCHKE, Christina et al. Tumor microenvironment: no effector T cells without dendritic cells. In: Cancer Cell, 2017, vol. 31, n° 5, p. 614–615. doi: 10.1016/j.ccell.2017.04.007
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Journal ISSN1535-6108
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