Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNg-Secreting Lymphocytes and IL12-Producing Dendritic Cells

Pfirschke, Christina; Zilionis, Rapolas; Engblom, Camilla; Messemaker, Marius; Zou, Angela E.; Rickelt, Steffen; Gort-Freitas, Nicolas A.; Lin, Yunkang; Bill, Ruben; Siwicki, Marie; Gungabeesoon, Jeremy; Sprachman, Melissa M.; Marquard, Angela N.; Rodell, Christopher B.; Cuccarese, Michael F.; Quintana, Jeremy; Ahmed, Maaz S.; Kohler, Rainer H.; Savova, Virginia; Weissleder, Ralph; Klein, Allon M.; Pittet, Mikaël

doi:10.1158/2326-6066.CIR-21-0326

Scientific article

English

Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNg-Secreting Lymphocytes and IL12-Producing Dendritic Cells

Published inCancer immunology research, vol. 10, no. 1, p. 40-55

Publication date2022-01

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Comprendre et manipuler le système immunitaire pour lutter contre le cancer (1024)

Funding

Swiss National Science Foundation - Targeting the tumor endothelium to sensitize lung cancer to immune checkpoint inhibition [183852]

Citation (ISO format)

PFIRSCHKE, Christina et al. Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNg-Secreting Lymphocytes and IL12-Producing Dendritic Cells. In: Cancer immunology research, 2022, vol. 10, n° 1, p. 40–55. doi: 10.1158/2326-6066.CIR-21-0326