The chemical biology of IL-12 production via the non-canonical NFkB pathway

Koch, Peter D.; Pittet, Mikaël; Weissleder, Ralph

doi:10.1039/d0cb00022a

Scientific article

Review

Open access

English

The chemical biology of IL-12 production via the non-canonical NFkB pathway

ContributorsKoch, Peter D.

; Pittet, Mikaël

; Weissleder, Ralph

Published inRSC chemical biology, vol. 1, no. 4, p. 166-176

Publication date2020

First online date2020

Abstract

Interleukin-12 (IL-12) has emerged as an attractive cytokine for cancer therapy because it has direct anti-cancer effects and additionally plays a critical role in enhancing checkpoint inhibitors.

Affiliation Not a UNIGE publication

Research group

Comprendre et manipuler le système immunitaire pour lutter contre le cancer (1024)

Citation (ISO format)

KOCH, Peter D., PITTET, Mikaël, WEISSLEDER, Ralph. The chemical biology of IL-12 production via the non-canonical NFkB pathway. In: RSC chemical biology, 2020, vol. 1, n° 4, p. 166–176. doi: 10.1039/d0cb00022a

Article (Published version)

CC BY-3.0

Identifiers

PID : unige:169000
DOI : 10.1039/d0cb00022a
PMID : 34458756
PMCID : PMC8341911

Commercial URLhttp://xlink.rsc.org/?DOI=D0CB00022A

ISSN of the journal2633-0679

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The chemical biology of IL-12 production via the non-canonical NFkB pathway

Interleukin-12 (IL-12) has emerged as an attractive cytokine for cancer therapy because it has direct anti-cancer effects and additionally plays a critical role in enhancing checkpoint inhibitors.

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