Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy

Ho, William W.; Gomes-Santos, Igor L.; Aoki, Shuichi; Datta, Meenal; Kawaguchi, Kosuke; Talele, Nilesh P.; Roberge, Sylvie; Ren, Jun; Liu, Hao; Chen, Ivy X.; Andersson, Patrik; Chatterjee, Sampurna; Kumar, Ashwin S.; Amoozgar, Zohreh; Zhang, Qixian; Huang, Peigen; Ng, Mei Rosa; Chauhan, Vikash P.; Xu, Lei; Duda, Dan G.; Clark, Jeffrey W.; Pittet, Mikaël; Fukumara, Dai; Jain, Rakesh K.

doi:10.1073/pnas.2105323118

Scientific article

English

Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy

Published inProceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 45, e2105323118

Publication date2021-11-09

Affiliation entities

Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
Faculté de médecine / Section de médecine clinique / Département de médecine

Research groups

Comprendre et manipuler le système immunitaire pour lutter contre le cancer (1024)

Citation (ISO format)

HO, William W. et al. Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy. In: Proceedings of the National Academy of Sciences of the United States of America, 2021, vol. 118, n° 45, p. e2105323118. doi: 10.1073/pnas.2105323118

Article (Published version)

CC BY-NC-ND-4.0

Identifiers

PID : unige:169022
DOI : 10.1073/pnas.2105323118
PMID : 34725151

Journal ISSN0027-8424

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Dendritic cell paucity in mismatch repair–proficient colorectal cancer liver metastases limits immune checkpoint blockade efficacy

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