en
Scientific article
Comment
English

ER stress in dendritic cells promotes cancer

Published inCell, vol. 161, no. 7, p. 1492-1493
Publication date2015
Abstract

XBP1 is part of the ER stress response, and when activated in cancer cells, it fosters tumor growth. In this issue of Cell, Cubillos-Ruiz et al. demonstrate that XBP1 in tumor-infiltrating dendritic cells blunts anti-tumor immunity. These findings further imply XBP1 as a relevant target for cancer therapy.

Keywords
  • Animals
  • DNA-Binding Proteins/metabolism
  • Dendritic Cells/pathology
  • Endoplasmic Reticulum Stress
  • Female
  • Humans
  • Ovarian Neoplasms/immunology/pathology
  • Transcription Factors/metabolism
Affiliation Not a UNIGE publication
Citation (ISO format)
GARRIS, Christopher S, PITTET, Mikaël. ER stress in dendritic cells promotes cancer. In: Cell, 2015, vol. 161, n° 7, p. 1492–1493. doi: 10.1016/j.cell.2015.06.006
Main files (1)
Article (Published version)
accessLevelRestricted
Identifiers
ISSN of the journal0092-8674
104views
0downloads

Technical informations

Creation07/08/2021 5:42:00 PM
First validation07/08/2021 5:42:00 PM
Update time03/16/2023 1:06:36 AM
Status update03/16/2023 1:06:36 AM
Last indexation01/17/2024 1:59:06 PM
All rights reserved by Archive ouverte UNIGE and the University of GenevaunigeBlack