CS
Samer, Caroline Flora
Affiliation entities
Research groups
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Improving Understanding of Fexofenadine Pharmacokinetics to Assess Pgp Phenotypic Activity in Older Adult Patients Using Population Pharmacokinetic Modeling | Clinical pharmacokinetics | 2025 | 15 | 7 | |||
The Impact of Dexamethasone and Prednisone on Apixaban and Rivaroxaban Exposure in COVID-19 Patients : A Physiologically Based Pharmacokinetic Modeling Study | Clinical pharmacology & therapeutics | 2025 | 20 | 18 | |||
Virtual twin approach using physiologically based pharmacokinetic modelling in hospitalized patients treated with apixaban or rivaroxaban | British journal of clinical pharmacology | 2025 | 13 | 0 | |||
Consent as a compositional act - a framework that provides clarity for the retention and use of data | Philosophy, ethics, and humanities in medicine | 2024 | 69 | 41 | |||
Guidance on selecting optimal steady-state tacrolimus concentrations for continuous IV perfusion : insights from physiologically based pharmacokinetic modeling | Pharmaceuticals | 2024 | 50 | 29 | |||
Enhancing Response Rates in Web-Based Surveys: The Impact of Direct Participant Contact | Healthcare | 2024 | 75 | 60 | |||
Stereoselective separation of omeprazole and 5-hydroxy-omeprazole using dried plasma spots and a heart-cutting 2D-LC approach for accurate CYP2C19 phenotyping | Journal of chromatography. B | 2024 | 64 | 57 | |||
Antiviral Use in Mild-to-Moderate SARS-CoV-2 Infections during the Omicron Wave in Geriatric Patients | Viruses | 2024 | 75 | 31 | |||
Impact of a Mobile App (LoAD Calc) on the Calculation of Maximum Safe Doses of Local Anesthetics : Protocol for a Randomized Controlled Trial | JMIR research protocols | 2024 | 101 | 23 | |||
Local anaesthetics risks perception : a web-based survey | Heliyon | 2024 | 44 | 19 | |||
In vitro screening of UGT2B10 in silico prioritized putative ligands from drugs used in the pediatric hematopoietic stem cell transplantation setting | Pharmacology research & perspectives | 2024 | 29 | 12 | |||
CYP450 3A4/5 Containment During SARS-CoV-2 Infection | Clinical pharmacology & therapeutics | 2023 | 32 | 42 | |||
Practice of CYP450 genotyping and phenotyping in children in a real-life setting | Frontiers in pharmacology | 2023 | 49 | 42 | |||
Development and retrospective evaluation of a clinical decision support system for the efficient detection of drug-related problems by clinical pharmacists | International journal of clinical pharmacy | 2023 | 121 | 42 | |||
Apixaban and rivaroxaban's physiologically-based pharmacokinetic model validation in hospitalized patients: A first step for larger use of a priori modeling approach at bed side | CPT: pharmacometrics & systems pharmacology | 2023 | 115 | 87 | |||
REPRESENT : REPresentativeness of RESearch data obtained through the 'General Informed ConsENT' | BMC medical ethics | 2023 | 97 | 37 | |||
Evaluation of Pupillometry for CYP2D6 Phenotyping in Children Treated with Tramadol | Pharmaceuticals | 2023 | 44 | 18 | |||
Polygenic risk scores in pharmacogenomics : opportunities and challenges-a mini review | Frontiers in genetics | 2023 | 62 | 20 | |||
Case report : Hepatotoxicity and nephrotoxicity induced by methotrexate in a paediatric patient, what is the role of precision medicine in 2023 ? | Frontiers in pharmacology | 2023 | 70 | 23 | |||
Population pharmacokinetics of apixaban in a real-life hospitalized population from the OptimAT study | CPT: pharmacometrics & systems pharmacology | 2023 | 71 | 61 | |||
Hydromorphone Prescription for Pain in Children - What Place in Clinical Practice? | Frontiers in pediatrics | 2022 | 129 | 53 | |||
Editorial: Precision Medicine: Impact of Cytochromes P450 and Transporters Genetic Polymorphisms, Drug-Drug Interactions, Disease on Safety and Efficacy of Drugs | Frontiers in pharmacology | 2022 | 154 | 100 | |||
Evaluation of CYP1A2 activity: Relationship between the endogenous urinary 6-hydroxymelatonin to melatonin ratio and paraxanthine to caffeine ratio in dried blood spots | Clinical and translational science | 2022 | 200 | 77 | |||
Dexamethasone exposure in normal-weight and obese hospitalized COVID-19 patients: An observational exploratory trial | Clinical and translational science | 2022 | 113 | 59 | |||
Impact of the Genotype and Phenotype of CYP3A and P-gp on the Apixaban and Rivaroxaban Exposure in a Real-World Setting | Journal of personalized medicine | 2022 | 181 | 159 | |||
Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics | CPT: pharmacometrics & systems pharmacology | 2022 | 220 | 294 | |||
Cyber harassment of female scientists will not be the new norm | The Lancet Infectious Diseases | 2021 | 217 | 176 | |||
Impact of SARS-CoV-2 Infection (COVID-19) on Cytochromes P450 Activity Assessed by the Geneva Cocktail | Clinical pharmacology and therapeutics | 2021 | 169 | 90 | |||
Development and Preliminary Validation of LoAD Calc, a Mobile App for Calculating the Maximum Safe Single Dose of Local Anesthetics | Healthcare | 2021 | 149 | 65 | |||
Drug-Drug Interactions Leading to Adverse Drug Reactions with Rivaroxaban: A Systematic Review of the Literature and Analysis of VigiBase | Journal of personalized medicine | 2021 | 181 | 67 | |||
Case Report: Low Hematocrit Leading to Tacrolimus Toxicity | Frontiers in pharmacology | 2021 | 191 | 98 | |||
Drug-drug interactions with direct oral anticoagulants: practical recommendations for clinicians | The American journal of medicine | 2021 | 126 | 0 | |||
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2D6, OPRM1, and COMT Genotypes and Select Opioid Therapy | Clinical Pharmacology and Therapeutics | 2021 | 203 | 2 | |||
Mixing Drugs and Genetics: A Complex Hemorrhagic Cocktail | American Journal of Medicine | 2021 | 245 | 5 | |||
CYP450 Genotype-Phenotype Concordance Using the Geneva Micrococktail in a Clinical Setting | Frontiers in pharmacology | 2021 | 233 | 105 | |||
Live vaccines and immunosuppressive monoclonal antibodies: weighing up the benefit-risk assessment for natalizumab | Journal of Travel Medicine | 2021 | 180 | 1 | |||
Impact of computerised physician order entry (CPOE) on the incidence of chemotherapy-related medication errors: a systematic review | European journal of clinical pharmacology | 2021 | 271 | 158 | |||
Influence of Inflammation on Cytochromes P450 Activity in Adults: A Systematic Review of the Literature | Frontiers in pharmacology | 2021 | 166 | 227 | |||
Electronic monitoring of potential adverse drug events related to lopinavir/ritonavir and hydroxychloroquine during the first wave of COVID-19 | European journal of hospital pharmacy | 2021 | 173 | 0 | |||
Medical cannabis or cannabinoids for chronic pain: a clinical practice guideline | BMJ | 2021 | 182 | 2 | |||
Impact of Inflammation on Cytochromes P450 Activity in Pediatrics: A Systematic Review | Clinical pharmacokinetics | 2021 | 189 | 72 | |||
Reviewing Data Integrated for PBPK Model Development to Predict Metabolic Drug-Drug Interactions: Shifting Perspectives and Emerging Trends | Frontiers in pharmacology | 2021 | 138 | 135 | |||
Citizens' Participation in Health and Scientific Research in Switzerland | Studies in Health Technology and Informatics | 2020 | 432 | 96 | |||
The Swiss Cheese Prescribing Model for Precision Medicine | American Journal of Medicine | 2020 | 247 | 165 | |||
Drug interactions with apixaban: A systematic review of the literature and an analysis of VigiBase, the World Health Organization database of spontaneous safety reports | Pharmacology Research and Perspectives | 2020 | 272 | 131 | |||
Early experimental COVID-19 therapies: associations with length of hospital stay, mortality and related costs | Swiss Medical Weekly | 2020 | 454 | 326 | |||
Impact of acute inflammation on cytochromes P450 activity assessed by the Geneva Cocktail | Clinical Pharmacology and Therapeutics | 2020 | 284 | 359 | |||
Vitamin D and glaucoma: a critical review of the literature | Journal of Ophthalmology | 2020 | 567 | 160 | |||
Automatic Classification of Discharge Letters to Detect Adverse Drug Reactions | Studies in Health Technology and Informatics | 2020 | 408 | 131 | |||
Evaluation of Phenotypic and Genotypic Variations of Drug Metabolising Enzymes and Transporters in Chronic Pain Patients Facing Adverse Drug Reactions or Non-Response to Analgesics: A Retrospective Study | Journal of Personalized Medicine | 2020 | 320 | 80 | |||
Interaction between Fexofenadine and CYP Phenotyping Probe Drugs in Geneva Cocktail | Journal of Personalized Medicine | 2019 | 366 | 163 | |||
Safety issues of pharmacological acute pain treatment in children | Clinical Pharmacology and Therapeutics | 2019 | 365 | 4 | |||
Cytochrome P450 1A2 activity and incidence of thyroid disease and cancer after chronic or acute exposure to dioxins | Basic & Clinical Pharmacology & Toxicology | 2019 | 410 | 4 | |||
Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment | Integrative Cancer Therapies | 2019 | 336 | 112 | |||
Toward precision medicine in pediatric population using cytochrome P450 phenotyping approaches and physiologically based pharmacokinetic modeling | Pediatric Research | 2019 | 292 | 2 | |||
The European Association for Clinical Pharmacology and Therapeutics-25 years' young and going strong | European Journal of Clinical Pharmacology | 2019 | 291 | 228 | |||
Impact of Boosted Antiretroviral Therapy on the Pharmacokinetics and Efficacy of Clopidogrel and Prasugrel Active Metabolites | Clinical Pharmacokinetics | 2018 | 619 | 655 | |||
Complex Drug-Drug-Gene-Disease Interactions Involving Cytochromes P450: Systematic Review of Published Case Reports and Clinical Perspectives | Clinical Pharmacokinetics | 2018 | 479 | 640 | |||
Prevention of potentially inappropriate medication in internal medicine patients: a prospective study using the electronic application PIM-check | Journal of Clinical Pharmacy and Therapeutics | 2018 | 375 | 3 | |||
When the Safe Alternative Is Not That Safe: Tramadol Prescribing in Children | Frontiers in Pharmacology | 2018 | 509 | 226 | |||
Cost-effectiveness of HLA-DQB1/HLA-B pharmacogenetic-guided treatment and blood monitoring in US patients taking clozapine | The Pharmacogenomics Journal | 2018 | 603 | 211 | |||
Severe and persistent morphine-induced respiratory depression associated with ATP-Binding Cassette Subfamily B Member 1 and catechol-O-methyltransferase genetic defects: A case report | European Journal of Anaesthesiology | 2018 | 412 | 250 | |||
Apixaban Pharmacokinetics at Steady State in Hemodialysis Patients | Journal of the American Society of Nephrology | 2017 | 532 | 3 | |||
Cytochromes P450 activity and functionality: biomarker of drug response and valuable tool for Precision Medicine | 2017 | 566 | 17 | ||||
Pharmacogénomique et thérapie personnalisée | Revue médicale suisse | 2017 | 473 | 202 | |||
Creation of the Swiss group of Pharmacogenomics and personalised Therapy (SPT) | Drug Metabolism and Personalized Therapy | 2017 | 480 | 1 | |||
Grundlagen und praktische Hinweise fur pharmakogenetische Tests : Personalisierte Therapie bei Psychopharmaka = Notions de base et aspects pratiques à propos de tests pharmacogénétiques : pharmacogénomique et thérapie personnalisée | InFo Neurologie und Psychiatrie | 2017 | 371 | 2 | |||
Characterization of oxycodone in vitro metabolism by human cytochromes P450 and UDP-glucuronosyltransferases | Journal of pharmaceutical and biomedical analysis | 2017 | 603 | 582 | |||
Screening for genotypic and phenotypic variations in CYP450 activity in patients with therapeutic problems in a psychiatric setting, a retrospective study | Pharmacological research | 2017 | 621 | 159 | |||
"Late" Withdrawal Syndrome after Carbamazepine In Utero Exposure in a CYP2C9 Slow Metabolizer Newborn | Frontiers in Pharmacology | 2017 | 581 | 194 | |||
Impact d'une réconciliation médicamenteuse par un pharmacien lors de l'admission dans un service de médecine interne | Le Pharmacien Hospitalier et Clinicien | 2017 | 249 | 181 | |||
PIM-Check: development of an international prescription-screening checklist designed by a Delphi method for internal medicine patients | BMJ Open | 2017 | 698 | 338 | |||
Notions de base et aspects pratiques à propos de tests pharmacogénétiques : pharmacogénomique et thérapie personnalisée = Grundlagen und praktische Hinweise für pharmakogenetische Tests : Personalisierte Therapie bei Psychopharmaka | InFo Neurologie und Psychiatrie | 2017 | 336 | 3 | |||
Letter by Bouatou et al Regarding Article, "Polypharmacy and the Efficacy and Safety of Rivaroxaban Versus Warfarin in the Prevention of Stroke in Patients With Nonvalvular Atrial Fibrillation" | Circulation | 2016 | 523 | 3 | |||
Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect | Frontiers in pharmacology | 2016 | 442 | 208 | |||
Coadministration of ticagrelor and ritonavir: Toward prospective dose adjustment to maintain an optimal platelet inhibition using the PBPK approach | Clinical pharmacology and therapeutics | 2016 | 599 | 656 | |||
Une histoire qui ne manque pas de mordant | Revue médicale suisse | 2016 | 342 | 192 | |||
HIV-Positive-to-HIV-Positive Liver Transplantation | American journal of transplantation | 2016 | 618 | 374 | |||
Evaluation of Mutual Drug-Drug Interaction within Geneva Cocktail for Cytochrome P450 Phenotyping using Innovative Dried Blood Sampling Method | Basic & clinical pharmacology & toxicology | 2016 | 630 | 382 | |||
Direct oral anticoagulants: efficacy and safety in patient subgroups | Schweizerische medizinische Wochenschrift | 2015 | 782 | 430 | |||
Dolutegravir-based antiretroviral therapy in a severely overweight child with a multidrug-resistant human immunodeficiency virus infection. A case report and review | New microbes and new infections | 2015 | 580 | 1 | |||
Corrigendum to "Dolutegravir-based antiretroviral therapy in a severely overweight child with a multi-drug resistant human immunodeficiency virus infection. A case report and review" [New Microbes New Infect] 6 (2015) 1-4] | New microbes and new infections | 2015 | 465 | 0 | |||
Providing Quality Therapeutics in Switzerland: Role of the Stakeholders and Recent Incentives for Further Improvements | Clinical therapeutics | 2015 | 677 | 6 | |||
Evidence-Based Choice of P2Y12 Inhibitors in End Stage Renal Disease Patients: A Mini-Review | Current drug metabolism | 2015 | 609 | 6 | |||
Drug-related problems identification in general internal medicine: The impact and role of the clinical pharmacist and pharmacologist | European journal of internal medicine | 2015 | 708 | 6 | |||
Prediction by pharmacogenetics of safety and efficacy of non-steroidal anti- inflammatory drugs: a review | Current drug metabolism | 2014 | 625 | 0 | |||
Geneva Cocktail for Cytochrome P450 and P-glycoprotein Activity Assessment Using Dried Blood Spots | Clinical pharmacology and therapeutics | 2014 | 842 | 340 | |||
Therapeutic drug monitoring of voriconazole: a case report of multiple drug interactions in a patient with an increased CYP2C19 activity | AIDS research and therapy | 2014 | 661 | 914 | |||
Prediction of Metabolic Interactions With Oxycodone via CYP2D6 and CYP3A Inhibition Using a Physiologically Based Pharmacokinetic Model | CPT: pharmacometrics & systems pharmacology | 2014 | 584 | 229 | |||
Simultaneous LC-MS/MS quantification of P-glycoprotein and cytochrome P450 probe substrates and their metabolites in DBS and plasma | Bioanalysis | 2014 | 720 | 5 | |||
Hepatic fat loss in advanced nonalcoholic steatohepatitis: are alterations in serum adiponectin the cause? | Hepatology | 2013 | 436 | 454 | |||
Pharmacokinetic interaction between prasugrel and ritonavir in healthy volunteers | Basic & clinical pharmacology & toxicology | 2013 | 604 | 383 | |||
Clinical Course and Management of Iatrogenic Cushing's Syndrome after Co-Administration of Injected-Triamcinolone and Ritonavir: a Systematic Review | Journal of Antivirals and Antiretrovirals | 2013 | 1,193 | 254 | |||
Traiter efficacement la douleur incidente chez l'adulte. Donnez le bon antalgique au bon moment | Revue médicale suisse | 2013 | 861 | 476 | |||
Carbimazole-induced, ANCA-associated, crescentic glomerulonephritis: case report and literature review | Renal failure | 2013 | 534 | 364 | |||
Applications of CYP450 Testing in the Clinical Setting | Molecular diagnosis & therapy | 2013 | 664 | 800 | |||
Pulmonary embolism and iatrogenic Cushing's syndrome after co-administration of injected-triamcinolone and ritonavir | AIDS | 2013 | 521 | 294 | |||
Human urinary biomarkers of dioxin exposure: Analysis by metabolomics and biologically driven data dimensionality reduction | Toxicology letters | 2013 | 655 | 1,019 | |||
Serotonin syndrome following drug-drug interactions and CYP2D6 and CYP2C19 genetic polymorphisms in an HIV-infected patient | AIDS | 2012 | 588 | 523 | |||
Quel programme informatique de détection des interactions médicamenteuses néfastes ? | Revue médicale suisse | 2012 | 927 | 894 | |||
Oral flurbiprofen metabolic ratio assessment using a single-point dried blood spot | Clinical pharmacology and therapeutics | 2012 | 604 | 0 | |||
Moving towards dose individualization of tyrosine kinase inhibitors | Cancer treatment reviews | 2011 | 428 | 540 | |||
Automated system for on-line desorption of dried blood spots applied to LC/MS/MS pharmacokinetic study of flurbiprofen and its metabolite | Journal of pharmaceutical and biomedical analysis | 2011 | 702 | 762 | |||
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone | British journal of pharmacology | 2010 | 735 | 2 | |||
Impact of genetic polymorphisms and drug-drug interactions on clopidogrel and prasugrel response variability | Current drug metabolism | 2010 | 636 | 0 | |||
Réactions d'hypersensibilité immédiates aux anti-inflammatoires non stéroïdiens: allergie ou pseudo-allergie? | Revue médicale suisse | 2010 | 641 | 1 | |||
Genetic polymorphisms and drug interactions modulating CYP2D6 and CYP3A activities have a major effect on oxycodone analgesic efficacy and safety | British journal of pharmacology | 2010 | 577 | 1 | |||
Pharmacogenetics of analgesics: toward the individualization of prescription | Pharmacogenomics | 2008 | 544 | 0 | |||
Impact des cytochromes P450 2D6 et 3A sur les paramètres pharmacocinétiques et pharmacodynamiques de l'oxycodone | 2008 | 809 | 513 | ||||
Polymorphisme génétique et interactions médicamenteuses: leur importance dans le traitement de la douleur | Canadian journal of anaesthesia | 2005 | 492 | 386 |