Dolutegravir-based antiretroviral therapy in a severely overweight child with a multidrug-resistant human immunodeficiency virus infection. A case report and review

Wagner, Noémie; Wyler, Claire-Anne; Yerly Ferrillo, Sabine; Samer, Caroline Flora; Peytavin, G; Posfay Barbe, Klara; Calmy, Alexandra; Ambrosioni Czyrko, Juan

doi:10.1016/j.nmni.2015.02.003

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Title		Dolutegravir-based antiretroviral therapy in a severely overweight child with a multidrug-resistant human immunodeficiency virus infection. A case report and review
Authors		Wagner, Noémie Wyler, Claire-Anne Yerly Ferrillo, Sabine Samer, Caroline Flora Peytavin, G Posfay Barbe, Klara Calmy, Alexandra Ambrosioni Czyrko, Juan
Published in		New Microbes and New Infections. 2015, vol. 6, p. 1-4
Abstract		The management of multidrug-resistant human immunodeficiency virus (MDR HIV) infections in children is particularly challenging due to the lack of experience with new drugs. Dolutegravir, combined with an optimized antiretroviral background therapy, is promising for the treatment of MDR HIV and has been approved recently for adults and adolescents. Data for children are extremely limited. We describe the efficacy, safety and plasmatic levels of a dolutegravir-based, complex active antiretroviral treatment regimen in a severely overweight 11-year-old child infected with an MDR HIV strain.
Identifiers		DOI: 10.1016/j.nmni.2015.02.003 PMID: 26082840
Full text		Article (Published version) (237 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups		Groupe Desmeules Jules (pharmacologie/toxicologie) (567) Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
Citation (ISO format)		WAGNER, Noémie et al. Dolutegravir-based antiretroviral therapy in a severely overweight child with a multidrug-resistant human immunodeficiency virus infection. A case report and review. In: New Microbes and New Infections, 2015, vol. 6, p. 1-4. doi: 10.1016/j.nmni.2015.02.003 https://archive-ouverte.unige.ch/unige:76220