TB
Brun, Thierry
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| In situ metabolomics reveals intra-islet metabolite changes upon in vivo stimulation of insulin secretion | The Journal of biological chemistry |  | 2025 | 42 | 21 | ||
| Faut-il redynamiser l'apprentissage par problèmes ? Une analyse de curriculum de formation médicale à la faculté de médecine de Genève | Congrès de la Société International Francophone en Éducation Médicale (SIFEM) 2025 | | 2025 | 79 | 98 | ||
| Analyse de la formation préclinique en médecine humaine à Genève: Rapport de synthèse des enquêtes réalisées entre novembre 2022 et juillet 2023 | | 2024 | 12 | 25 | |||
| Dietary protein load affects the energy and nitrogen balance requiring liver glutamate dehydrogenase to maintain physical activity | The Journal of biological chemistry | | 2024 | 99 | 30 | ||
| Glucolipotoxicity promotes the capacity of the glycerolipid/NEFA cycle supporting the secretory response of pancreatic beta cells | Diabetologia |  | 2022 | 227 | 1 | ||
| Palmitate and oleate modify membrane fluidity and kinase activities of INS-1E β-cells alongside altered metabolism-secretion coupling | Biochimica et Biophysica Acta - Molecular Cell Research | | 2020 | 560 | 8 | ||
| Mitochondrial carriers regulating insulin secretion profiled in human islets upon metabolic stress | Biomolecules | | 2020 | 237 | 72 | ||
| AMPK profiling in rodent and human pancreatic beta-cells under nutrient-rich metabolic stress | International Journal of Molecular Sciences | | 2020 | 338 | 181 | ||
| L'exposition des cellules bêta au fructose potentialise la sécrétion d'insuline via une signalisation par l'ATP | Revue médicale suisse | | 2019 | 464 | 193 | ||
| Chronic fructose renders pancreatic beta-cells hyper-responsive to glucose-stimulated insulin secretion through extracellular ATP signaling | American Journal of Physiology. Endocrinology and Metabolism | | 2019 | 835 | 1,152 | ||
| Beta-cell mitochondrial carriers and the diabetogenic stress response | Biochimica et biophysica acta | | 2016 | 490 | 486 | ||
| Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets | Human molecular genetics | | 2015 | 715 | 329 | ||
| Changes in mitochondrial carriers exhibit stress-specific signatures in INS-1Eβ-cells exposed to glucose versus fatty acids | PloS one | | 2013 | 745 | 438 | ||
| NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion | Diabetes | | 2012 | 811 | 527 | ||
| Mitochondrial dysfunction in pancreatic β cells | Trends in endocrinology and metabolism | | 2012 | 588 | 4 | ||
| Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E beta-cells and human islets through a SIRT1-dependent mechanism | The Journal of biological chemistry | | 2011 | 648 | 1 | ||
| In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice | Diabetes | | 2011 | 701 | 1,581 | ||
| Peroxisome proliferator-activated receptor alpha (PPARalpha) protects against oleate-induced INS-1E beta cell dysfunction by preserving carbohydrate metabolism | Diabetologia | | 2010 | 819 | 120 | ||
| Role of mitochondria in beta-cell function and dysfunction | Advances in experimental medicine and biology | 2010 | 640 | 0 | |||
| Transient oxidative stress damages mitochondrial machinery inducing persistent beta-cell dysfunction | The Journal of biological chemistry | | 2009 | 508 | 668 | ||
| The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1 | Human molecular genetics | | 2008 | 699 | 0 | ||
| A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease | Journal of molecular endocrinology | | 2008 | 560 | 0 | ||
| The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells | Oncogene | | 2007 | 652 | 0 | ||
| The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression | Molecular endocrinology | | 2005 | 614 | 0 | ||
| The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets | The Journal of cell biology | | 2004 | 592 | 656 | ||
| Agenesis of human pancreas due to decreased half-life of insulin promoter factor 1 | The Journal of clinical endocrinology and metabolism | | 2003 | 636 | 0 | ||
| Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription | Diabetologia | | 2003 | 696 | 189 | ||
| Metabolic fate of glucose in purified islet cells | The Journal of biological chemistry | | 1997 | 155 | 205 | ||
| Regulation of acetyl-CoA carboxylase gene expression by nutrients in the pancreatic β-cell | | 1994 | 739 | 191 | |||
| Glucose regulates acetyl-CoA carboxylase gene expression in a pancreatic beta-cell line (INS-1) | The Journal of biological chemistry | | 1993 | 137 | 104 |
