The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1
Published inHuman molecular genetics, vol. 17, no. 4, p. 478-489
Publication date2008
Abstract
Keywords
- Activins/pharmacology
- Animals
- Antigens CD95/genetics
- Cell Proliferation/drug effects
- Diabetes Mellitus Type 2/complications/genetics/metabolism
- Epigenesis Genetic
- Gene Expression
- Glucagon-Like Peptide 1/pharmacology
- Glucose/pharmacology
- Homeodomain Proteins/genetics/metabolism
- Humans
- Insulin/secretion
- Insulin-Secreting Cells/cytology/drug effects/metabolism/secretion
- Intercellular Signaling Peptides and Proteins/pharmacology
- Interleukin-1beta/genetics
- Islets of Langerhans/drug effects/metabolism/secretion
- Mitogens/pharmacology
- Obesity/complications/genetics/metabolism
- Paired Box Transcription Factors/genetics/metabolism
- RNA Messenger/genetics/metabolism
- Rats
- Signal Transduction
- Transfection
Research group
Citation (ISO format)
BRUN, Thierry et al. The diabetes-linked transcription factor Pax4 is expressed in human pancreatic islets and is activated by mitogens and GLP-1. In: Human molecular genetics, 2008, vol. 17, n° 4, p. 478–489. doi: 10.1093/hmg/ddm325
Main files (1)
Article (Accepted version)
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Identifiers
- PID : unige:765
- DOI : 10.1093/hmg/ddm325
- PMID : 17989064
Commercial URLhttp://hmg.oxfordjournals.org/cgi/content/full/17/4/478
ISSN of the journal1460-2083