| Signalomics for molecular tumor boards and precision oncology of breast and gynecological cancers | Molecular systems biology |  | | 2025 | 70 | 41 |
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| Loss of the conserved switch III region in a G protein leads to severe pediatric encephalopathy | Science signaling |  | | 2025 | 22 | 0 |
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| Clinical-molecular profiling of atypical GNAO1 patients : Novel pathogenic variants, unusual manifestations, and severe molecular dysfunction | Genes & diseases | | | 2025 | 41 | 30 |
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| Success and Controversy of Natural Products as Therapeutic Modulators of Wnt Signaling and Its Interplay with Oxidative Stress : Comprehensive Review Across Compound Classes and Experimental Systems | Antioxidants | | | 2025 | 48 | 509 |
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| Syndecan-2 positively regulates Wnt/β-catenin signaling in breast cancer cells | International journal of biochemistry & cell biology | | | 2025 | 40 | 0 |
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| Atypical GNAO1 variants in severe childhood speech disorders: clinical, genetic, and molecular insights | Molecular autism | | | 2025 | 17 | 26 |
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| Integration of Wnt-inhibitory activity and structural novelty scoring results to uncover novel bioactive natural products : new Bicyclo[3.3.1]non-3-ene-2,9-diones from the leaves of Hymenocardia punctata | Frontiers in chemistry | | | 2024 | 129 | 118 |
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| Germline mutations in a G protein identify signaling cross-talk in T cells | Science | | | 2024 | 187 | 0 |
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| Neomorphic Gαo mutations gain interaction with Ric8 proteins in GNAO1 encephalopathies | The Journal of clinical investigation | | | 2024 | 102 | 111 |
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| Zinc for GNAO1 encephalopathy : preclinical profiling and a clinical case | Med | | | 2024 | 135 | 348 |
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| Challenging Reported Frizzled-Targeting Compounds in Selective Assays Reveals Lack of Functional Inhibition and Claimed Profiles | ACS pharmacology & translational science | | | 2024 | 201 | 123 |
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| Chemical and Biological Characterization of Metabolites from Silene viridiflora Using Mass Spectrometric and Cell-Based Assays | Biomolecules | | | 2024 | 100 | 415 |
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| Clinical and Molecular Profiling in GNAO1 Permits Phenotype–Genotype Correlation | Movement disorders | | | 2024 | 103 | 221 |
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| GNAO1 Mutations Affecting the N‐Terminal α‐Helix of Gαo Lead to Parkinsonism | Movement disorders | | | 2024 | 119 | 265 |
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| Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic evolutionary response to malnutrition in Drosophila | PLOS genetics | | | 2024 | 75 | 210 |
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| Clinical Cases and the Molecular Profiling of a Novel Childhood Encephalopathy-Causing GNAO1 Mutation P170R | Cells | | | 2023 | 120 | 92 |
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| Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells | Microbiology spectrum | | | 2023 | 190 | 229 |
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| Shallow- and deep-water Ophiura species produce a panel of chlorin compounds with potent photodynamic anticancer activities | Antioxidants | | | 2023 | 248 | 96 |
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| Clofazimine: a journey of a drug | Biomedicine & pharmacotherapy | | | 2023 | 102 | 383 |
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| In-depth molecular profiling of an intronic GNAO1 mutant as the basis for personalized high-throughput drug screening | Med | | | 2023 | 139 | 1 |
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| Pediatric GNAO1 encephalopathies: from molecular etiology of the disease to drug discovery | Neural Regeneration Research | | | 2023 | 111 | 194 |
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| Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells | iScience | | | 2023 | 95 | 78 |
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| Gαi2-induced conductin/axin2 condensates inhibit Wnt/β-catenin signaling and suppress cancer growth | Nature communications | | | 2022 | 382 | 299 |
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| Wnt-pathway inhibitors with selective activity against triple-negative breast cancer: from thienopyrimidine to quinazoline inhibitors | Frontiers in pharmacology | | | 2022 | 217 | 238 |
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| Chemoenzymatic synthesis of complex phenylpropanoid derivatives by the Botrytis cinerea secretome and evaluation of their wnt inhibition activity | Frontiers in plant science | | | 2022 | 310 | 211 |
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| Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea pers | Frontiers in chemistry | | | 2022 | 241 | 222 |
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| Restoration of the GTPase activity and cellular interactions of Gαo mutants by Zn2+ in GNAO1 encephalopathy models | Science advances | | | 2022 | 212 | 201 |
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| Mouse models characterize GNAO1 encephalopathy as a neurodevelopmental disorder leading to motor anomalies: from a severe G203R to a milder C215Y mutation | Acta neuropathologica communications | | | 2022 | 280 | 161 |
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| Mining natural compounds to target WNT signaling: land and sea tales | Pharmacology of the WNT signaling system | | | 2021 | 226 | 1 |
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| Pediatric encephalopathy: cinical, biochemical and cellular insights into the role of Gln52 of GNAO1 and GNAI1 for the dominant disease | Cells | | | 2021 | 409 | 243 |
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| A cytotoxic porphyrin from North Pacific brittle star Ophiura sarsii | Marine Drugs | | | 2021 | 496 | 249 |
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| Optimization of the clofazimine structure leads to a highly water-soluble C3-aminopyridinyl riminophenazine endowed with improved anti-Wnt and anti-cancer activity in vitro and in vivo | European Journal of Medicinal Chemistry | | | 2021 | 290 | 215 |
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| Unlocking the Wnt pathway : therapeutic potential of selective targeting FZD7 in cancer | Drug discovery today | | | 2021 | 550 | 538 |
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| Short stature and combined immunodeficiency associated with mutations in RGS10 | Science Signaling | | | 2021 | 236 | 0 |
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| Isolation and identification of isocoumarin derivatives with specific inhibitory activity against wnt pathway and metabolome characterization of lasiodiplodia venezuelensis | Frontiers in Chemistry | | | 2021 | 376 | 1,008 |
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| Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells | Communications Biology | | | 2021 | 349 | 232 |
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| Generation of stilbene antimicrobials against multiresistant strains of Staphylococcus aureus through biotransformation by the enzymatic secretome of Botrytis cinerea | Journal of Natural Products | | | 2020 | 365 | 565 |
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| Beyond TNBC: repositioning of clofazimine against a broad range of Wnt-dependent cancers | Frontiers in Oncology | | | 2020 | 342 | 285 |
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| Targeting the Wnt signalling pathway in cancer: prospects and perils | Swiss Medical Weekly | | | 2019 | 599 | 392 |
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| Chemo-diversification of plant extracts using a generic bromination reaction and monitoring by metabolite profiling | ACS Combinational Science | | | 2019 | 412 | 0 |
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| A high-throughput assay pipeline for specific targeting of frizzled GPCRs in cancer | Methods in Cell Biology |  | | 2019 | 367 | 0 |
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| Towards the first targeted therapy for triple-negative breast cancer: Repositioning of clofazimine as a chemotherapy-compatible selective Wnt pathway inhibitor | Cancer Letters | | | 2019 | 1,151 | 526 |
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| Dramatic dysbalancing of the Wnt pathway in breast cancers | Scientific Reports | | | 2018 | 318 | 174 |
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| High capacity in G protein-coupled receptor signaling | Nature Communications | | | 2018 | 394 | 223 |
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| Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts | Cancer Letters | | | 2018 | 340 | 876 |
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| High-throughput targeted screening in triple-negative breast cancer cells identifies Wnt-inhibiting activities in Pacific brittle stars | Scientific Reports | | | 2017 | 402 | 211 |
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| Golgi-Resident Gαo Promotes Protrusive Membrane Dynamics | Cell | | | 2017 | 484 | 499 |
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| Cardamonin, a chalcone, inhibits human triple negative breast cancer cell invasiveness by downregulation of Wnt/β-catenin signaling cascades and reversal of epithelial-mesenchymal transition | BioFactors | | | 2017 | 441 | 813 |
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| Inhibition of Wnt signalling and breast tumour growth by the multi-purpose drug suramin through suppression of heterotrimeric G proteins and Wnt endocytosis | Biochemical Journal | | | 2016 | 407 | 530 |
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| A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers | Cancers | | | 2016 | 420 | 433 |
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