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Leveraging multi-organ models for drug combination therapy safetyBiomedicine & pharmacotherapy
accessLevelPublic
2025 9 29
Microflow Liquid Chromatography Coupled to Multinozzle Electrospray Ionization for Improved Lipidomics Coverage of 3D Clear Cell Renal Cell CarcinomaAnalytical chemistry
accessLevelRestricted
2025 29 1
A cellular danse macabre: the choreography of programmed cell deathApoptosis
accessLevelRestricted
2025 27 0
Liposomal Tubacin: Strategies for the Formulation of a Highly Hydrophobic Anticancer DrugPharmaceutics
accessLevelPublic
2025 34 115
Preclinical Photodynamic Therapy Targeting Blood Vessels withAGuIX® Theranostic NanoparticlesCancers, 2024
accessLevelPublic
2024 31 23
Generation and maintenance of kidney and kidney cancer organoids from patient-derived material for drug development and precision oncologyMolecular therapy. Methods & clinical development
accessLevelPublic
2024 58 39
Challenges in validation of combination treatment strategies for CRC using patient-derived organoidsJournal of experimental & clinical cancer research
accessLevelPublic
2024 31 56
New melphalan derivatives for the treatment of retinoblastoma in combination with thermotherapyRSC medicinal chemistry
accessLevelPublic
2024 24 43
Nanoparticles Dysregulate the Human Placental Secretome with Consequences on Angiogenesis and VascularizationAdvanced science
accessLevelPublic
2024 26 98
Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancerCellular and molecular life sciences
accessLevelPublic
2023 122 224
Activation of endogenous glucocorticoids by HSD11B1 inhibits the antitumor immune response in renal cancerOncoimmunology
accessLevelPublic
2023 232 82
Advanced in vitro models for renal cell carcinoma therapy designBiochimica et biophysica acta, CR. Reviews on cancer
accessLevelPublic
2023 91 197
Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinomaJournal of experimental & clinical cancer research
accessLevelPublic
2023 176 69
Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapyNature communications
accessLevelPublic
2022 180 101
Proinflammatory activity of VEGF-targeted treatment through reversal of tumor endothelial cell anergyAngiogenesis
accessLevelPublic
2022 190 71
FOLFOXIRI Resistance Induction and Characterization in Human Colorectal Cancer CellsCancers
accessLevelPublic
2022 251 120
Characterization of Renal Cell Carcinoma Heterotypic 3D Co-Cultures with Immune Cell SubsetsCancers
accessLevelPublic
2021 166 209
Drug repurposing to identify a synergistic high-order drug combination to treat sunitinib-resistant renal cell carcinomaCancers
accessLevelPublic
2021 247 259
A quarter century of ApoptosisApoptosis
accessLevelRestricted
2021 218 1
COVID-19 is a systemic vascular hemopathy: insight for mechanistic and clinical aspectsAngiogenesis
accessLevelRestricted
2021 155 1
Anti-angiogenic agents - overcoming tumour endothelial cell anergy and improving immunotherapy outcomesNature reviews. Clinical oncology
accessLevelRestricted
2021 401 5
Molecular and Functional Analysis of Sunitinib-Resistance Induction in Human Renal Cell Carcinoma CellsInternational journal of molecular sciences
accessLevelPublic
2021 200 215
Forcing dividing cancer cells to die; low-dose drug combinations to prevent spindle pole clusteringApoptosis
accessLevelPublic
2021 214 113
Common mechanistic pathways in cancer and heart failure. A scientific roadmap on behalf of the Translational Research Committee of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC)European Journal of Heart Failure
accessLevelPublic
2020 232 240
Optimized low‐dose combinatorial drug treatment boosts selectivity and efficacy of colorectal carcinoma treatmentMolecular Oncology
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2020 439 183
Identification of low-dose multidrug combinations for sunitinib-naive and pre-treated renal cell carcinomaBritish Journal of Cancer
accessLevelPublic
2020 339 183
Integrating Phenotypic Search and Phosphoproteomic Profiling of Active Kinases for Optimization of Drug Mixtures for RCC TreatmentCancers
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2020 247 123
Optimized Combination of HDACI and TKI Efficiently Inhibits Metabolic Activity in Renal Cell Carcinoma and Overcomes Sunitinib ResistanceCancers
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2020 372 190
Optimization for multidrug combinations: Challenges and perspectives in complex disordersPharmacological Research
accessLevelRestricted
2020 387 4
Drug-Drug Interactions of Irinotecan, 5-Fluorouracil, Folinic Acid and Oxaliplatin and Its Activity in Colorectal Carcinoma TreatmentMolecules
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2020 380 253
Patient-Derived In Vitro Models for Drug Discovery in Colorectal CarcinomaCancers
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2020 342 259
Programmed death, cells on the last train to gloryApoptosis
accessLevelRestricted
2020 221 1
Anti-angiogenic effects of crenolanib are mediated by mitotic modulation independently of PDGFR expressionBritish Journal of Cancer
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2019 455 197
Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancerBiochimica et Biophysica Acta. Reviews on Cancer
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2019 488 702
Oncofoetal insulin receptor isoform A marks the tumour endothelium; an underestimated pathway during tumour angiogenesis and angiostatic treatmentBritish Journal of Cancer
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2019 325 151
Identification of a Synergistic Multi-Drug Combination Active in Cancer Cells via the Prevention of Spindle Pole ClusteringCancers
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2019 539 304
Colorectal Cancer Growth Retardation through Induction of Apoptosis, Using an Optimized Synergistic Cocktail of Axitinib, Erlotinib, and DasatinibCancers
accessLevelPublic
2019 289 102
Short-term 3D culture systems of various complexity for treatment optimization of colorectal carcinomaScientific Reports
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2019 444 260
An improved conjugate vaccine technology; induction of antibody responses to the tumor vasculatureVaccine
accessLevelPublic
2018 319 236
Targeting PDGF-mediated recruitment of pericytes blocks vascular mimicry and tumor growthThe Journal of Pathology
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2018 259 151
Apoptosis on the moveApoptosis
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2018 241 107
IGF2 and IGF1R identified as novel tip cell genes in primary microvascular endothelial cell monolayersAngiogenesis
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2018 263 178
Consensus guidelines for the use and interpretation of angiogenesis assaysAngiogenesis
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2018 834 1,015
Development of an Efficient Dual-Action GST-Inhibiting Anticancer Platinum(IV) ProdrugChemMedChem
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2018 385 310
Apoptosis turns 21Apoptosis
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2017 214 110
Epigenetic approach for angiostatic therapy: promising combinations for cancer treatmentAngiogenesis
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2017 298 386
Angiogenesis inhibitors in combinatorial approachesAngiogenesis
accessLevelRestricted
2017 234 0
Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapyMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis
accessLevelRestricted
2017 206 0
A genomic screen for angiosuppressor genes in the tumor endothelium identifies a multifaceted angiostatic role for bromodomain containing 7 (BRD7)Angiogenesis
accessLevelPublic
2017 279 128
Current Trends in Multidrug Optimization: An Alley of Future Successful Treatment of Complex DisordersSLAS technology
accessLevelRestricted
2017 244 5
miRNAs: micro-managers of anticancer combination therapiesAngiogenesis
accessLevelRestricted
2017 224 0
Insulin-like growth factor axis targeting in cancer and tumour angiogenesis - the missing linkBiological Reviews
accessLevelPublic
2017 251 213
Combination of ruthenium(II)-arene complex [Ru(η6-p-cymene)Cl2(pta)] (RAPTA-C) and the epidermal growth factor receptor inhibitor erlotinib results in efficient angiostatic and antitumor activityScientific Reports
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2017 288 180
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