Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma
ContributorsRamzy, George Mourad; Norkin, Maxim; Kossler, Thibaud; Voirol, Lionel
; Tihy, Matthieu; Hany, Dina
; Mckee, Thomas Alexander; Ris, Frédéric; Buchs, Nicolas; Docquier, Mylene; Toso, Christian; Rubbia-Brandt, Laura; Bakalli, Gaetan; Guerrier, Stéphane; Huelsken, Joerg; Nowak-Sliwinska, Patrycja



Published inJournal of experimental & clinical cancer research, vol. 42, no. 1, 79
Publication date2023-04-03
First online date2023-04-03
Abstract
Keywords
- Drug‑drug interaction
- Drug resistance
- Multidrug combination
- Organoid
- Phenotypic screen
- Synergy
- Targeted RNAseq
Affiliation
- Faculté des sciences / Section des sciences pharmaceutiques
- Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
- Faculté de médecine / Section de médecine clinique / Département de chirurgie
- Centres et instituts / Institut de génétique et de génomique
- Faculté de médecine / Section de médecine clinique / Département de médecine
- Faculté des sciences / Section de biologie / Département de génétique et évolution
- Faculté d'économie et de management / Research Center for Statistics
Funding
- European Commission - Optimized drug combinations for effective cancer treatment: a personalised approach. [680209]
- Swiss National Science Foundation - Synergistic targeted drug combinations for induction of sensitivity to immune checkpoint inhibitors. [197878]
Citation (ISO format)
RAMZY, George Mourad et al. Platform combining statistical modeling and patient-derived organoids to facilitate personalized treatment of colorectal carcinoma. In: Journal of experimental & clinical cancer research, 2023, vol. 42, n° 1, p. 79. doi: 10.1186/s13046-023-02650-z
Main files (1)
Article (Published version)
Secondary files (1)
Identifiers
- PID : unige:168618
- DOI : 10.1186/s13046-023-02650-z
- PMID : 37013646
ISSN of the journal1756-9966