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Title

Consensus guidelines for the use and interpretation of angiogenesis assays

Authors
Alitalo, Kari
Allen, Elizabeth
Anisimov, Andrey
Aplin, Alfred C
Auerbach, Robert
Augustin, Hellmut G
Bates, David O
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Published in Angiogenesis. 2018
Abstract The formation of new blood vessels, or angiogenesis, is a complex process that plays important roles in growth and development, tissue and organ regeneration, as well as numerous pathological conditions. Angiogenesis undergoes multiple discrete steps that can be individually evaluated and quantified by a large number of bioassays. These independent assessments hold advantages but also have limitations. This article describes in vivo, ex vivo, and in vitro bioassays that are available for the evaluation of angiogenesis and highlights critical aspects that are relevant for their execution and proper interpretation. As such, this collaborative work is the first edition of consensus guidelines on angiogenesis bioassays to serve for current and future reference.
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PMID: 29766399
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Article (Published version) (11.6 MB) - public document Free access
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Research group L'athérosclérose (665)
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NOWAK-SLIWINSKA, Patrycja et al. Consensus guidelines for the use and interpretation of angiogenesis assays. In: Angiogenesis, 2018. https://archive-ouverte.unige.ch/unige:104612

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Deposited on : 2018-05-22

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