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When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing

Published inFrontiers in Microbiology, vol. 9, 1566
Publication date2018
Abstract

Here, we sequenced DNA extracted from a necrotic hepatic lesion from a patient with suspected chronic hepatic brucelloma but negative culture results. Although most of the taxonomically classified sequencing reads corresponded to human genome sequences, our data suggest that whole-metagenome shotgun sequencing may be used together with other tests to strengthen the diagnosis of hepatic brucelloma.

Citation (ISO format)
LAZAREVIC, Vladimir et al. When Bacterial Culture Fails, Metagenomics Can Help: A Case of Chronic Hepatic Brucelloma Assessed by Next-Generation Sequencing. In: Frontiers in Microbiology, 2018, vol. 9, p. 1566. doi: 10.3389/fmicb.2018.01566
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ISSN of the journal1664-302X
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