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Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box | Molecular and cellular endocrinology | 2012 | 581 | 1 412 | |||
Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass | Cell metabolism | 2011 | 579 | 0 | |||
Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | The Journal of biological chemistry | 2011 | 564 | 0 | |||
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | 2011 | 676 | 0 | |||
Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Diabetes, obesity & metabolism | 2011 | 600 | 0 | |||
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation | Biochimica et biophysica acta | 2010 | 583 | 2 | |||
Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | International journal of biochemistry & cell biology | 2009 | 640 | 0 | |||
TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis | Journal of Endocrinology | 2008 | 541 | 0 | |||
The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells | Molecular and cellular biology | 2008 | 459 | 0 | |||
Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy | The Journal of biological chemistry | 2007 | 715 | 350 | |||
Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets | Genes and immunity | 2007 | 569 | 0 | |||
Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | 2005 | 590 | 147 | |||
Does chasing selected 'Fox' to the nucleus prevent diabetes? | Trends in molecular medicine | 2005 | 576 | 360 | |||
The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation | Cell metabolism | 2005 | 516 | 596 | |||
Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity | Diabetologia | 2004 | 548 | 167 | |||
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death | The Journal of biological chemistry | 2002 | 522 | 314 | |||
Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release | The Journal of biological chemistry | 2002 | 498 | 199 | |||
Experimental models of transcription factor-associated maturity-onset diabetes of the young | Diabetes | 2002 | 598 | 0 | |||
Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation | The Journal of biological chemistry | 2001 | 600 | 1 600 | |||
Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice | Endocrinology | 2001 | 538 | 0 | |||
Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion | The Journal of biological chemistry | 2000 | 578 | 220 | |||
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells | The Journal of clinical investigation | 1999 | 568 | 231 | |||
Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells | Diabetes | 1999 | 712 | 0 | |||
Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line | EMBO journal | 1998 | 536 | 288 | |||
Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell | The Journal of biological chemistry | 1998 | 572 | 218 |