HW
Publications
25
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16,409
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1 - 25 of 25
Title Published in Access level OA Policy Year Views Downloads
Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC boxMolecular and cellular endocrinology
2012 667 1,644
Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and massCell metabolism
2011 648 0
Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stressThe Journal of biological chemistry
2011 629 0
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosisHuman molecular genetics
2011 811 0
Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivoDiabetes, obesity & metabolism
2011 676 0
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidationBiochimica et biophysica acta
2010 645 2
Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosisInternational journal of biochemistry & cell biology
2009 751 0
TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosisJournal of Endocrinology
2008 645 0
The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cellsMolecular and cellular biology
2008 524 0
Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancyThe Journal of biological chemistry
2007 808 441
Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic isletsGenes and immunity
2007 634 0
Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cellsDiabetologia
2005 648 224
Does chasing selected 'Fox' to the nucleus prevent diabetes?Trends in molecular medicine
2005 648 524
The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formationCell metabolism
2005 589 708
Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivityDiabetologia
2004 614 193
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell deathThe Journal of biological chemistry
2002 590 376
Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin releaseThe Journal of biological chemistry
2002 562 347
Experimental models of transcription factor-associated maturity-onset diabetes of the youngDiabetes
2002 677 0
Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiationThe Journal of biological chemistry
2001 667 1,726
Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic miceEndocrinology
2001 624 0
Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretionThe Journal of biological chemistry
2000 652 340
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cellsThe Journal of clinical investigation
1999 632 358
Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cellsDiabetes
1999 822 0
Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell lineEMBO journal
1998 601 389
Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cellThe Journal of biological chemistry
1998 645 269
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