| Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box | Molecular and cellular endocrinology | | | 2012 | 669 | 1,690 |
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| Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and mass | Cell metabolism | | | 2011 | 650 | 0 |
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| Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | The Journal of biological chemistry | | | 2011 | 631 | 0 |
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| The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | | | 2011 | 813 | 0 |
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| Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Diabetes, obesity & metabolism | | | 2011 | 678 | 0 |
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| Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation | Biochimica et biophysica acta | | | 2010 | 648 | 2 |
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| Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | International journal of biochemistry & cell biology | | | 2009 | 753 | 0 |
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| TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis | Journal of Endocrinology | | | 2008 | 647 | 0 |
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| The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells | Molecular and cellular biology | | | 2008 | 527 | 0 |
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| Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy | The Journal of biological chemistry | | | 2007 | 810 | 448 |
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| Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets | Genes and immunity | | | 2007 | 636 | 0 |
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| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | | | 2005 | 650 | 232 |
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| Does chasing selected 'Fox' to the nucleus prevent diabetes? | Trends in molecular medicine | | | 2005 | 650 | 546 |
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| The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation | Cell metabolism | | | 2005 | 591 | 728 |
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| Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity | Diabetologia | | | 2004 | 616 | 195 |
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| Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death | The Journal of biological chemistry | | | 2002 | 592 | 394 |
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| Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release | The Journal of biological chemistry | | | 2002 | 564 | 359 |
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| Experimental models of transcription factor-associated maturity-onset diabetes of the young | Diabetes | | | 2002 | 679 | 0 |
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| Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation | The Journal of biological chemistry | | | 2001 | 669 | 1,761 |
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| Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice | Endocrinology | | | 2001 | 626 | 0 |
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| Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion | The Journal of biological chemistry | | | 2000 | 654 | 351 |
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| Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells | The Journal of clinical investigation | | | 1999 | 634 | 386 |
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| Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells | Diabetes | | | 1999 | 824 | 0 |
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| Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line | EMBO journal | | | 1998 | 603 | 399 |
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| Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell | The Journal of biological chemistry | | | 1998 | 647 | 276 |
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