HW
Publications
25
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Title Published in Access level OA Policy Year Views Downloads
Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC boxMolecular and cellular endocrinology
accessLevelPublic
2012 660 1,555
Bace2 is a β cell-enriched protease that regulates pancreatic β cell function and massCell metabolism
accessLevelRestricted
2011 641 0
Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stressThe Journal of biological chemistry
accessLevelRestricted
2011 621 0
The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosisHuman molecular genetics
accessLevelRestricted
2011 803 0
Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivoDiabetes, obesity & metabolism
accessLevelRestricted
2011 670 0
Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidationBiochimica et biophysica acta
accessLevelRestricted
2010 636 2
Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosisInternational journal of biochemistry & cell biology
accessLevelRestricted
2009 746 0
TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosisJournal of Endocrinology
accessLevelRestricted
2008 630 0
The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cellsMolecular and cellular biology
accessLevelRestricted
2008 515 0
Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancyThe Journal of biological chemistry
accessLevelPublic
2007 800 385
Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic isletsGenes and immunity
accessLevelRestricted
2007 628 0
Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cellsDiabetologia
accessLevelPublic
2005 642 174
Does chasing selected 'Fox' to the nucleus prevent diabetes?Trends in molecular medicine
accessLevelPublic
2005 641 458
The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formationCell metabolism
accessLevelPublic
2005 579 633
Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivityDiabetologia
accessLevelPublic
2004 608 173
Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell deathThe Journal of biological chemistry
accessLevelPublic
2002 583 351
Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin releaseThe Journal of biological chemistry
accessLevelPublic
2002 554 276
Experimental models of transcription factor-associated maturity-onset diabetes of the youngDiabetes
accessLevelRestricted
2002 670 0
Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiationThe Journal of biological chemistry
accessLevelPublic
2001 655 1,647
Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic miceEndocrinology
accessLevelRestricted
2001 613 0
Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretionThe Journal of biological chemistry
accessLevelPublic
2000 647 300
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cellsThe Journal of clinical investigation
accessLevelPublic
1999 621 293
Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cellsDiabetes
accessLevelRestricted
1999 816 0
Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell lineEMBO journal
accessLevelPublic
1998 594 341
Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cellThe Journal of biological chemistry
accessLevelPublic
1998 637 235
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