Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion
Published inThe Journal of biological chemistry, vol. 275, no. 46, p. 35953-35959
Publication date2000
Abstract
Keywords
- Adenosine Triphosphate/metabolism
- Animals
- Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone/pharmacology
- DNA-Binding Proteins
- Dose-Response Relationship, Drug
- Doxycycline/pharmacology
- Gene Expression Regulation/drug effects
- Genes, Reporter
- Glucose/metabolism/pharmacology
- Hepatocyte Nuclear Factor 4
- Insulin/secretion
- Islets of Langerhans/drug effects/metabolism/secretion
- Leucine/pharmacology
- Membrane Potentials/drug effects
- Mitochondria/drug effects/metabolism
- Phosphoproteins/genetics/metabolism
- Promoter Regions, Genetic
- Pyruvic Acid/metabolism
- RNA, Messenger/genetics/metabolism
- Rats
- Recombinant Fusion Proteins/metabolism
- Time Factors
- Transcription Factors/genetics/metabolism
- Tumor Cells, Cultured
Citation (ISO format)
WANG, Haiyan et al. Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion. In: The Journal of biological chemistry, 2000, vol. 275, n° 46, p. 35953–35959. doi: 10.1074/jbc.M006612200
Main files (1)
Article (Published version)
Identifiers
- PID : unige:35181
- DOI : 10.1074/jbc.M006612200
- PMID : 10967120
ISSN of the journal0021-9258