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Title

From genotype to antibiotic susceptibility phenotype in the order Enterobacterales: a clinical perspective

Authors
Schicklin, S.
Published in Clinical Microbiology and Infection. 2020, vol. 26, no. 5, p. 643.e1-643.e7
Abstract Objectives: Predicting the antibiotic susceptibility phenotype from genomic data is challenging, especially for some specific antibiotics in the order Enterobacterales. Here we aimed to assess the performance of whole genomic sequencing (WGS) for predicting the antibiotic susceptibility in various Enterobacterales species using the detection of antibiotic resistance genes (ARGs), specific mutations and a knowledge-based decision algorithm.
Keywords Antibiotic resistanceAntibiotic resistance genesAntibiotic susceptibility testingBioinformaticsInferenceWhole-genome sequencing
Identifiers
PMID: 31586657
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Other version: https://linkinghub.elsevier.com/retrieve/pii/S1198743X19305038
Structures
Research group Analyse génomique et fonctionnelle du staphylocoque doré (604)
Citation
(ISO format)
RUPPE, Etienne et al. From genotype to antibiotic susceptibility phenotype in the order Enterobacterales: a clinical perspective. In: Clinical Microbiology and Infection, 2020, vol. 26, n° 5, p. 643.e1-643.e7. doi: 10.1016/j.cmi.2019.09.018 https://archive-ouverte.unige.ch/unige:140152

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Deposited on : 2020-08-24

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