Glycine increases fat‐free mass in malnourished haemodialysis patients: a randomized double‐blind crossover trial

Genton Graf, Laurence; Teta, Daniel; Pruijm, Menno; Stoermann Chopard, Catherine Augusta; Marangon, Nicola Danièle Armando; Mareschal, Julie; Bassi, Isabelle; Wurzner‐Ghajarzadeh, Arelene; Lazarevic, Vladimir; Cynober, Luc; Cani, Patrice D.; Herrmann, François; Schrenzel, Jacques

doi:10.1002/jcsm.12780

Scientific article

English

Glycine increases fat‐free mass in malnourished haemodialysis patients: a randomized double‐blind crossover trial

ContributorsGenton Graf, Laurence

; Teta, Daniel; Pruijm, Menno; Stoermann Chopard, Catherine Augusta; Marangon, Nicola Danièle Armando; Mareschal, Julie; Bassi, Isabelle; Wurzner‐Ghajarzadeh, Arelene; Lazarevic, Vladimir

; Cynober, Luc; Cani, Patrice D.; Herrmann, François; Schrenzel, Jacques

Published inJournal of cachexia, sarcopenia and muscle

First online date2021-09-14

Abstract

Background: Protein energy wasting is associated with negative outcome in patients under chronic haemodialysis (HD). Branched-chain amino acids (BCAAs) may increase the muscle mass. This post hoc analysis of a controlled double-blind randomized crossover study assessed the impact of BCAAs on nutritional status, physical function, and quality of life.

Keywords

Amino acids
Body composition
Lean body mass
Malnutrition

Affiliation entities

Research groups

Funding

Swiss National Science Foundation - Do branched chain amino acids counteract protein energy wasting through gut microbiota changes in hemodialysis patients? [320030_163144]

Citation (ISO format)

GENTON GRAF, Laurence et al. Glycine increases fat‐free mass in malnourished haemodialysis patients: a randomized double‐blind crossover trial. In: Journal of cachexia, sarcopenia and muscle, 2021. doi: 10.1002/jcsm.12780

Article (Published version)

CC BY-4.0

Appendix

Identifiers

PID : unige:157425
DOI : 10.1002/jcsm.12780
PMID : 34519439

Additional URL for this publicationhttps://onlinelibrary.wiley.com/doi/10.1002/jcsm.12780

Journal ISSN2190-5991

298views

402downloads

Creation30/11/2021 12:54:00

First validation30/11/2021 12:54:00

Update31/01/2025 16:27:58

Status update31/01/2025 16:27:58

Last indexation31/01/2025 16:31:10

Archive ouverte UNIGE

Glycine increases fat‐free mass in malnourished haemodialysis patients: a randomized double‐blind crossover trial

Technical informations