Imipenem heteroresistance in nontypeable Haemophilus influenzae is linked to a combination of altered PBP3, slow drug influx and direct efflux regulation
Published inClinical Microbiology and Infection, vol. 23, no. 2, p. 118.e9-118.e19
Publication date2017
Abstract
Keywords
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Amino Acid Substitution
- Anti-Bacterial Agents/pharmacology
- Bacterial Proteins/genetics
- Child
- Child, Preschool
- Female
- Genetic Variation
- Genome, Bacterial
- Haemophilus Infections/microbiology
- Haemophilus influenzae/classification/drug effects/genetics
- Humans
- Imipenem/pharmacology
- Infant
- Infant, Newborn
- Male
- Microbial Sensitivity Tests
- Microbial Viability/drug effects/genetics
- Middle Aged
- Molecular Typing
- Mutation
- Serotyping
- Young Adult
- beta-Lactam Resistance
Affiliation entities
Research groups
Citation (ISO format)
CHERKAOUI, Abdessalam et al. Imipenem heteroresistance in nontypeable Haemophilus influenzae is linked to a combination of altered PBP3, slow drug influx and direct efflux regulation. In: Clinical Microbiology and Infection, 2017, vol. 23, n° 2, p. 118.e9–118.e19. doi: 10.1016/j.cmi.2016.10.009
Main files (1)
Article (Published version)
Identifiers
- PID : unige:99565
- DOI : 10.1016/j.cmi.2016.10.009
- PMID : 27756711
Journal ISSN1198-743X
