Mon patient est trop âgé pour une statine : mythes et réalités

Article Autre article Mon patient est trop âgé pour une statine : mythes et réalités fre 2015 author Steenpass Veronika 845323 author Tahar Chaouche A author Mach François 27365 author Reny Jean-Luc 0000-0002-7528-7363 704339 author Ehret Georg Benedikt 98462 2110-2114 26727731 1660-9379 Lipid-lowering treatment in the elderly patient is conditioned by a high incidence and prevalence of cardiovascular disease in the setting of a limited remaining life span. The clinical benefit of statin therapy can be seen after a few months, thus supporting use in secondary prevention even when the lifespan is restricted to a few years. Recent guidelines propose the use of moderate doses in the elderly > 75 years. The evidence for treatment in primary prevention is weaker and the evaluation of the total cardiovascular risk is complicated by the high baseline risk of many elderly. Rational treatment decisions should be based on biologic rather than chronologic age. Statins are generally well tolerated in the elderly, requiring clinical monitoring only, with particular attention to pharmacokinetic interactions and renal failure. Age Factors Aged Aged, 80 and over Algorithms Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors/contraindications Hypolipidemic Agents/contraindications Dewey 610 Dewey 616 56 Département de médecine 221 false 11 Plaquettes et antithrombotiques 13 Revue médicale suisse 11 494 51b3553b-44aa-4119-b393-d361be372c91 Article (Published version) Restricted RMS_494_2110.pdf 511541 application/pdf restrictedAccess Faculté de médecine / Section de médecine clinique / Département de médecine

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Mon patient est trop âgé pour une statine : mythes et réalités	Revue médicale suisse			2015	469	0

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Steenpass, Veronika