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Title

Rapid molecular determination of methicillin resistance in staphylococcal bacteraemia improves early targeted antibiotic prescribing: a randomized clinical trial

Authors
Charles, Patrick G
Stewardson, Andrew J
Renzi, Gesuele
Rougemont, Mathieu
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Published in Clinical Microbiology and Infection. 2016
Abstract Empiric therapy of methicillin-susceptible Staphylococcus aureus (MSSA) with vancomycin is associated with poorer outcome than targeted therapy with beta-lactams. Our objective was to evaluate if rapid determination of methicillin resistance shortens the time from Gram stain to targeted antimicrobial therapy in staphylococcal bacteraemia, thereby reducing vancomycin overuse.
Identifiers
PMID: 27475737
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Structures
Research groups Groupe Harbarth Stephan (Staphylocoques dorés résistants à la méthicilline) (866)
Analyse génomique et fonctionnelle du staphylocoque doré (604)
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EMONET, Stéphane Paul et al. Rapid molecular determination of methicillin resistance in staphylococcal bacteraemia improves early targeted antibiotic prescribing: a randomized clinical trial. In: Clinical Microbiology and Infection, 2016. https://archive-ouverte.unige.ch/unige:87606

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Deposited on : 2016-09-21

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