Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice
Published inJournal of virology, vol. 89, no. 13, p. 6761-6772
Publication date2015
Abstract
Keywords
- Animals
- Disease Resistance
- Gene Knockdown Techniques
- Genetic Therapy/methods
- Genetic Vectors
- HIV Infections/immunology/virology
- HIV-1/physiology
- Hematopoietic Stem Cells/immunology/virology
- Humans
- Lentivirus/genetics
- Mice, SCID
- Receptors, CCR5/metabolism
- Receptors, HIV/antagonists & inhibitors
- Transplantation
- Viral Load
- Virus Attachment
Research group
Citation (ISO format)
MYBURGH, Renier et al. Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice. In: Journal of virology, 2015, vol. 89, n° 13, p. 6761–6772. doi: 10.1128/JVI.00277-15
Main files (1)
Article (Published version)
Identifiers
- PID : unige:82441
- DOI : 10.1128/JVI.00277-15
- PMID : 25903342
ISSN of the journal0022-538X