KK
Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
---|---|---|---|---|---|---|---|
NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice | RMD open | 2023 | 129 | 36 | |||
Articular cartilage repair after implantation of hyaline cartilage beads engineered from adult dedifferentiated chondrocytes: cartibeads preclinical efficacy study in a large animal model | The American journal of sports medicine | 2023 | 315 | 0 | |||
Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential | Biochimica et biophysica acta. Molecular cell research | 2023 | 163 | 61 | |||
Cancer spheroids and organoids as novel tools for research and therapy : state of the art and challenges to guide precision medicine | Cells | 2023 | 19 | 1 | |||
Adipose-derived stromal cells within a gelatin matrix acquire enhanced regenerative and angiogenic properties: a pre-clinical study for application to chronic wounds | Biomedicines | 2023 | 85 | 25 | |||
Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells | Microbiology spectrum | 2023 | 87 | 22 | |||
NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing | Redox biology | 2023 | 107 | 70 | |||
CCR5 deficiency: Decreased neuronal resilience to oxidative stress and increased risk of vascular dementia | Alzheimer's & dementia | 2023 | 143 | 66 | |||
Adipose-derived stem cell spheroids are superior to single-cell suspensions to improve fat autograft long-term survival | Journal of Cellular and Molecular Medicine | 2022 | 379 | 133 | |||
NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss | Frontiers in cell and developmental biology | 2022 | 280 | 43 | |||
Decreased Levels of SARS-CoV-2 Fusion-Inhibitory Antibodies in the Serum of Aged COVID-19 Patients | Diagnostics | 2022 | 129 | 50 | |||
Optimization of thymidine kinase-based safety switch for neural cell therapy | Cells | 2022 | 218 | 52 | |||
Hyaline cartilage microtissues engineered from adult dedifferentiated chondrocytes: safety and role of WNT signaling | Stem cells translational medicine | 2022 | 208 | 74 | |||
Transposon-Directed Insertion-Site Sequencing Reveals Glycolysis Gene gpmA as Part of the H2O2 Defense Mechanisms in Escherichia coli | Antioxidants | 2022 | 156 | 93 | |||
Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss | Frontiers in neurology | 2022 | 109 | 18 | |||
Transcriptomic Analysis of E. coli after Exposure to a Sublethal Concentration of Hydrogen Peroxide Revealed a Coordinated Up-Regulation of the Cysteine Biosynthesis Pathway | Antioxidants | 2022 | 106 | 54 | |||
Alpha-1 Antitrypsin Reduces Disease Progression in a Mouse Model of Charcot-Marie-Tooth Type 1A: A Role for Decreased Inflammation and ADAM-17 Inhibition | International journal of molecular sciences | 2022 | 195 | 106 | |||
Periodontitis and peri-implantitis in elderly people experiencing institutional and hospital confinement | Periodontology 2000 | 2022 | 146 | 78 | |||
A Cellular Assay for Spike/ACE2 Fusion: Quantification of Fusion-Inhibitory Antibodies after COVID-19 and Vaccination | Viruses | 2022 | 103 | 71 | |||
Adipose-Derived Stromal Cells for Chronic Wounds: Scientific Evidence and Roadmap Toward Clinical Practice | Stem cells translational medicine | 2022 | 94 | 38 | |||
Neurothreads: Development of supportive carriers for mature dopaminergic neuron differentiation and implantation | Biomaterials | 2021 | 150 | 77 | |||
Modeling poliovirus infection using human engineered neural tissue enriched with motor neuron derived from embryonic stem cells | Frontiers in Cell and Developmental Biology | 2021 | 298 | 76 | |||
Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects | Frontiers in cellular neuroscience | 2021 | 227 | 81 | |||
Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation | Frontiers in pharmacology | 2021 | 71 | 10 | |||
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation | Science signaling | 2021 | 139 | 0 | |||
Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis | Frontiers in immunology | 2021 | 136 | 60 | |||
Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant | Scientific reports | 2021 | 194 | 76 | |||
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells | Communications Biology | 2021 | 276 | 174 | |||
Di-tyrosine crosslinking and NOX4 expression as oxidative pathological markers in the lungs of patients with idiopathic pulmonary fibrosis | Antioxidants | 2021 | 158 | 76 | |||
Intrinsically Self-renewing Neuroprogenitors From the A/J Mouse Spiral Ganglion as Virtually Unlimited Source of Mature Auditory Neurons | Frontiers in cellular neuroscience | 2020 | 147 | 125 | |||
Induced pluripotent stem cells to understand mucopolysaccharidosis. i: demonstration of a migration defect in neural precursors | Cells | 2020 | 185 | 85 | |||
Redox activation of excitatory pathways in auditory neurons as mechanism of age-related hearing loss | Redox Biology | 2020 | 280 | 123 | |||
Generation of human induced pluripotent stem cell line UNIGEi003-A from skin fibroblasts of an apparently healthy male donor | Stem cell research | 2020 | 146 | 39 | |||
Regenerative Secretoma of Adipose-Derived Stem Cells from Ischemic Patients | Journal of Stem Cell Research & Therapy | 2019 | 312 | 178 | |||
Navigating in vitro bioactivity data by investigating available resources using model compounds | Scientific Data | 2019 | 309 | 8 | |||
Fate of systemically and locally administered adipose-derived mesenchymal stromal cells and their effect on wound healing | Stem Cells Translational Medicine | 2019 | 282 | 207 | |||
Poly-Lactic Acid-Based Biopolymer Formulations Are Safe for Sustained Intratympanic Dexamethasone Delivery | Otology & Neurotology | 2019 | 329 | 0 | |||
Optimizing synthetic miRNA minigene architecture for efficient miRNA hairpin concatenation and multi-target gene knockdown | Molecular Therapy - Nucleic Acids | 2019 | 376 | 190 | |||
Implementation research for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva infection prevention and control (IPC)-think tank (part 1) | Antimicrobial Resistance and Infection Control | 2019 | 349 | 175 | |||
Generation of human induced pluripotent stem cell line UNIGEi001-A from a 2-years old patient with Mucopolysaccharidosis type IH disease | Stem Cell Research | 2019 | 327 | 159 | |||
Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2) | Antimicrobial Resistance and Infection Control | 2019 | 372 | 148 | |||
NADPH oxidase 4 regulates inflammation in ischemic heart failure: role of soluble epoxide hydrolase | Antioxidants & Redox Signaling | 2019 | 302 | 1 | |||
Pharmacological characterization of the seven human NOX isoforms and their inhibitors | Redox Biology | 2019 | 332 | 294 | |||
Broadening the infection prevention and control network globally; 2017 Geneva IPC-think tank (part 3) | Antimicrobial Resistance and Infection Control | 2019 | 344 | 152 | |||
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature | PLOS Pathogens | 2018 | 473 | 249 | |||
GROW: a model for mentorship to advance women's leadership in global health | Global Health, Epidemiology and Genomics | 2018 | 361 | 156 | |||
Altered Humoral Immune Responses and IgG Subtypes in NOX2-Deficient Mice and Patients: A Key Role for NOX2 in Antigen-Presenting Cells | Frontiers in Immunology | 2018 | 418 | 210 | |||
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC | Redox Biology | 2017 | 447 | 167 | |||
Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus | Redox Biology | 2017 | 422 | 165 | |||
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) | Redox Biology | 2017 | 516 | 650 | |||
Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse | Translational Psychiatry | 2017 | 572 | 169 | |||
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells | Stem Cell Research | 2017 | 461 | 235 | |||
NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence? | Free Radical Biology & Medicine | 2017 | 394 | 190 | |||
Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma | Cancer Cell | 2017 | 454 | 5 | |||
Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay | Archives of toxicology | 2017 | 633 | 447 | |||
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis | Free radical biology & medicine | 2016 | 602 | 241 | |||
Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease | FEMS microbiology reviews | 2016 | 524 | 3 | |||
NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury | Scientific Reports | 2016 | 566 | 189 | |||
NADPH oxidase 4 deficiency leads to impaired wound repair and reduced dityrosine-crosslinking, but does not affect myofibroblast formation | Free radical biology & medicine | 2016 | 472 | 273 | |||
A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC) | Lab on a chip | 2016 | 867 | 1 197 | |||
A subset of N-substituted phenothiazines inhibits NADPH oxidases | Free radical biology & medicine | 2015 | 543 | 499 | |||
Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice | Journal of virology | 2015 | 601 | 358 | |||
Phagocyte NADPH oxidase and specific immunity | Clinical science | 2015 | 596 | 2 | |||
Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways | Journal of pathology | 2015 | 887 | 328 | |||
NOX3-Targeted therapies for inner ear pathologies | Current pharmaceutical design | 2015 | 533 | 4 | |||
Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology | Antioxidants & redox signaling | 2015 | 640 | 0 | |||
Human three-dimensional engineered neural tissue reveals cellular and molecular events following cytomegalovirus infection | Biomaterials | 2015 | 775 | 8 | |||
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications | Antioxidants & redox signaling | 2015 | 500 | 362 | |||
NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome | International journal of clinical and experimental pathology | 2014 | 613 | 3 | |||
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery | Archives of toxicology | 2014 | 446 | 201 | |||
Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response | International journal of cancer | 2014 | 668 | 376 | |||
Transplantation cellulaire : traitements actuels et perspectives d'avenir | Revue médicale suisse | 2014 | 805 | 14 | |||
Engineering of midbrain organoids containing long-lived dopaminergic neurons | Stem cells and development | 2014 | 654 | 856 | |||
Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation | PLOS pathogens | 2014 | 754 | 264 | |||
Screening of bioactive peptides using an embryonic stem cell-based neurodifferentiation assay | The AAPS journal | 2014 | 540 | 213 | |||
Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases | BioResearch open access | 2014 | 517 | 552 | |||
HIV-1 Tat C modulates NOX2 and NOX4 expressions through miR-17 in a human microglial cell line | Journal of neurochemistry | 2014 | 459 | 452 | |||
Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction | Molecular therapy. Nucleic acids | 2014 | 503 | 209 | |||
The NADPH oxidase Nox2 regulates VEGFR1/CSF-1R-mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex | GLIA | 2013 | 591 | 1 | |||
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4 | Biochemical pharmacology | 2013 | 801 | 1 | |||
Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties | Arteriosclerosis, thrombosis, and vascular biology | 2013 | 604 | 0 | |||
Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress | Antioxidants & redox signaling | 2013 | 605 | 1 | |||
The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma | Biomaterials | 2013 | 639 | 6 | |||
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs | PloS one | 2013 | 555 | 327 | |||
Test systems of developmental toxicity: state-of-the art and future perspectives | Archives of toxicology | 2013 | 548 | 2 | |||
The role of immunosuppression in the transplantation of allogenic neural precursors derived from human pluripotent stem cells for Parkinson's disease | Stem cell research & therapy | 2013 | 884 | 252 | |||
Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury | Journal of Molecular and Cellular Cardiology | 2013 | 581 | 0 | |||
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach | Archives of toxicology | 2013 | 652 | 1 236 | |||
Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells | Current medicinal chemistry | 2013 | 648 | 0 | |||
Monocrotophos in Gandaman village: India school lunch deaths and need for improved toxicity testing | Archives of toxicology | 2013 | 508 | 145 | |||
NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion | Diabetes | 2012 | 721 | 456 | |||
Diabetes, comorbidities and increased long-term mortality in older patients admitted for geriatric inpatient care | Diabetes & metabolism | 2012 | 639 | 0 | |||
NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury | Journal of the American Society of Nephrology | 2012 | 505 | 0 | |||
Cellular diversity within embryonic stem cells: pluripotent clonal sublines show distinct differentiation potential | Journal of Cellular and Molecular Medicine | 2012 | 668 | 4 | |||
Telomere length, comorbidity, functional, nutritional and cognitive status as predictors of 5 years post hospital discharge survival in the oldest old | The Journal of nutrition, health & aging | 2012 | 591 | 53 | |||
Reactive oxygen species: from health to disease | Schweizerische medizinische Wochenschrift | 2012 | 4 395 | 2 794 | |||
NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology | Translational psychiatry | 2012 | 565 | 366 | |||
Targeting NOX enzymes in the central nervous system: therapeutic opportunities | Cellular and molecular life sciences | 2012 | 538 | 346 | |||
Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells | Journal of pathology | 2012 | 599 | 3 | |||
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases | Free radical biology & medicine | 2012 | 651 | 2 | |||
Extensive natural variation for cellular hydrogen peroxide release is genetically controlled | PloS one | 2012 | 678 | 374 | |||
Haplotype-based banking of human pluripotent stem cells for transplantation: potential and limitations | Stem cells and development | 2012 | 622 | 677 | |||
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network | Cell death and differentiation | 2012 | 625 | 309 | |||
Generation and applications of human pluripotent stem cells induced into neural lineages and neural tissues | Frontiers in physiology | 2012 | 594 | 795 | |||
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice | Nature communications | 2012 | 648 | 453 | |||
Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity | International journal of obesity | 2012 | 671 | 5 | |||
Prospective comparison of 6 comorbidity indices as predictors of 1-year post-hospital discharge institutionalization, readmission, and mortality in elderly individuals | Journal of the American Medical Directors Association | 2012 | 548 | 0 | |||
A key role for NOX4 in epithelial cell death during development of lung fibrosis | Antioxidants & redox signaling | 2011 | 698 | 5 | |||
High levels of comorbidity and disability cancel out the dementia effect in predictions of long-term mortality after discharge in the very old | Dementia and geriatric cognitive disorders | 2011 | 609 | 4 | |||
Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation | Cell death and differentiation | 2011 | 571 | 0 | |||
NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis | Nature medicine | 2011 | 524 | 1 | |||
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action | British journal of pharmacology | 2011 | 673 | 0 | |||
Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow | Blood | 2011 | 632 | 1 | |||
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism | PloS one | 2011 | 659 | 352 | |||
Mild cognitive impairment, degenerative and vascular dementia as predictors of intra-hospital, short- and long-term mortality in the oldest old | Aging Clinical and Experimental Research | 2011 | 633 | 25 | |||
TNF-α blockade in chronic granulomatous disease-induced hyperinflammation: patient analysis and murine model | Journal of allergy and clinical immunology | 2011 | 515 | 0 | |||
NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon | Molecular and cellular biology | 2010 | 576 | 0 | |||
Increased brain damage after ischaemic stroke in mice lacking the chemokine receptor CCR5 | British journal of pharmacology | 2010 | 761 | 1 | |||
The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses | The Journal of neuroscience | 2010 | 580 | 1 | |||
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing | Alternatives to animal experimentation | 2010 | 459 | 0 | |||
Prospective comparison of six co-morbidity indices as predictors of 5 years post hospital discharge survival in the elderly | Rejuvenation research | 2010 | 566 | 2 | |||
Geriatrics index of comorbidity was the most accurate predictor of death in geriatric hospital among six comorbidity scores | Journal of clinical epidemiology | 2010 | 685 | 0 | |||
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells | Circulation research | 2010 | 551 | 0 | |||
Telomere length is not predictive of dementia or MCI conversion in the oldest old | Neurobiology of aging | 2010 | 584 | 0 | |||
Calnexin deficiency leads to dysmyelination | The Journal of biological chemistry | 2010 | 540 | 0 | |||
Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries | Circulation | 2010 | 593 | 0 | |||
Invasive microsporidiosis in allogeneic haematopoietic SCT recipients | Bone marrow transplantation | 2010 | 520 | 0 | |||
Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death | Experimental cell research | 2010 | 493 | 0 | |||
Telomere length and ApoE polymorphism in mild cognitive impairment, degenerative and vascular dementia | Journal of the neurological sciences | 2010 | 615 | 1 | |||
Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model | Critical reviews in oncology/hematology | 2009 | 664 | 1 | |||
NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression | Journal of innate immunity | 2009 | 625 | 4 | |||
Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats | Biological psychiatry | 2009 | 594 | 0 | |||
Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation | Human mutation | 2009 | 585 | 0 | |||
Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2 | Cancer research | 2009 | 496 | 1 | |||
NOX enzymes in the central nervous system: from signaling to disease | Antioxidants & redox signaling | 2009 | 552 | 0 | |||
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation | Arteriosclerosis, thrombosis, and vascular biology | 2009 | 593 | 415 | |||
Does dementia predict adverse hospitalization outcomes? A prospective study in aged inpatients | International journal of geriatric psychiatry | 2009 | 513 | 0 | |||
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | Antioxidants & redox signaling | 2009 | 603 | 2 |