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Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
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Hepatic miR-149-5p upregulation fosters steatosis, inflammation and fibrosis development in mice and in human liver organoids | JHEP reports | 2024 | 27 | 19 | |||
NADPH oxidase 4 deficiency attenuates experimental osteoarthritis in mice | RMD open | 2023 | 167 | 53 | |||
Articular cartilage repair after implantation of hyaline cartilage beads engineered from adult dedifferentiated chondrocytes: cartibeads preclinical efficacy study in a large animal model | The American journal of sports medicine | 2023 | 368 | 0 | |||
Discovery and validation of new Hv1 proton channel inhibitors with onco-therapeutic potential | Biochimica et biophysica acta. Molecular cell research | 2023 | 185 | 72 | |||
Cancer spheroids and organoids as novel tools for research and therapy : state of the art and challenges to guide precision medicine | Cells | 2023 | 52 | 49 | |||
Adipose-derived stromal cells within a gelatin matrix acquire enhanced regenerative and angiogenic properties: a pre-clinical study for application to chronic wounds | Biomedicines | 2023 | 109 | 41 | |||
Wnt-Independent SARS-CoV-2 Infection in Pulmonary Epithelial Cells | Microbiology spectrum | 2023 | 118 | 47 | |||
NADPH oxidase 4 is dispensable for skin myofibroblast differentiation and wound healing | Redox biology | 2023 | 126 | 103 | |||
CCR5 deficiency: Decreased neuronal resilience to oxidative stress and increased risk of vascular dementia | Alzheimer's & dementia | 2023 | 170 | 101 | |||
Adipose-derived stem cell spheroids are superior to single-cell suspensions to improve fat autograft long-term survival | Journal of Cellular and Molecular Medicine | 2022 | 406 | 151 | |||
NADPH Oxidase 3 Deficiency Protects From Noise-Induced Sensorineural Hearing Loss | Frontiers in cell and developmental biology | 2022 | 340 | 65 | |||
Decreased Levels of SARS-CoV-2 Fusion-Inhibitory Antibodies in the Serum of Aged COVID-19 Patients | Diagnostics | 2022 | 141 | 77 | |||
Optimization of thymidine kinase-based safety switch for neural cell therapy | Cells | 2022 | 248 | 64 | |||
Hyaline cartilage microtissues engineered from adult dedifferentiated chondrocytes: safety and role of WNT signaling | Stem cells translational medicine | 2022 | 275 | 88 | |||
Transposon-Directed Insertion-Site Sequencing Reveals Glycolysis Gene gpmA as Part of the H2O2 Defense Mechanisms in Escherichia coli | Antioxidants | 2022 | 183 | 123 | |||
Development and in vivo validation of small interfering RNAs targeting NOX3 to prevent sensorineural hearing loss | Frontiers in neurology | 2022 | 140 | 34 | |||
Transcriptomic Analysis of E. coli after Exposure to a Sublethal Concentration of Hydrogen Peroxide Revealed a Coordinated Up-Regulation of the Cysteine Biosynthesis Pathway | Antioxidants | 2022 | 133 | 67 | |||
Alpha-1 Antitrypsin Reduces Disease Progression in a Mouse Model of Charcot-Marie-Tooth Type 1A: A Role for Decreased Inflammation and ADAM-17 Inhibition | International journal of molecular sciences | 2022 | 223 | 116 | |||
Periodontitis and peri-implantitis in elderly people experiencing institutional and hospital confinement | Periodontology 2000 | 2022 | 155 | 113 | |||
A Cellular Assay for Spike/ACE2 Fusion: Quantification of Fusion-Inhibitory Antibodies after COVID-19 and Vaccination | Viruses | 2022 | 123 | 90 | |||
Adipose-Derived Stromal Cells for Chronic Wounds: Scientific Evidence and Roadmap Toward Clinical Practice | Stem cells translational medicine | 2022 | 123 | 58 | |||
Neurothreads: Development of supportive carriers for mature dopaminergic neuron differentiation and implantation | Biomaterials | 2021 | 173 | 83 | |||
Modeling poliovirus infection using human engineered neural tissue enriched with motor neuron derived from embryonic stem cells | Frontiers in Cell and Developmental Biology | 2021 | 315 | 88 | |||
Local Cisplatin Delivery in Mouse Reliably Models Sensorineural Ototoxicity Without Systemic Adverse Effects | Frontiers in cellular neuroscience | 2021 | 265 | 91 | |||
Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation | Frontiers in pharmacology | 2021 | 94 | 27 | |||
Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca2+ signaling during T cell activation | Science signaling | 2021 | 170 | 0 | |||
Hydrogen Peroxide Affects Growth of S. aureus Through Downregulation of Genes Involved in Pyrimidine Biosynthesis | Frontiers in immunology | 2021 | 171 | 75 | |||
Concurrent mutations in RNA-dependent RNA polymerase and spike protein emerged as the epidemiologically most successful SARS-CoV-2 variant | Scientific reports | 2021 | 212 | 90 | |||
Macropinocytosis requires Gal-3 in a subset of patient-derived glioblastoma stem cells | Communications Biology | 2021 | 293 | 181 | |||
Di-tyrosine crosslinking and NOX4 expression as oxidative pathological markers in the lungs of patients with idiopathic pulmonary fibrosis | Antioxidants | 2021 | 176 | 94 | |||
Intrinsically Self-renewing Neuroprogenitors From the A/J Mouse Spiral Ganglion as Virtually Unlimited Source of Mature Auditory Neurons | Frontiers in cellular neuroscience | 2020 | 213 | 147 | |||
Induced pluripotent stem cells to understand mucopolysaccharidosis. i: demonstration of a migration defect in neural precursors | Cells | 2020 | 213 | 101 | |||
Redox activation of excitatory pathways in auditory neurons as mechanism of age-related hearing loss | Redox Biology | 2020 | 302 | 136 | |||
Generation of human induced pluripotent stem cell line UNIGEi003-A from skin fibroblasts of an apparently healthy male donor | Stem cell research | 2020 | 176 | 62 | |||
Regenerative Secretoma of Adipose-Derived Stem Cells from Ischemic Patients | Journal of Stem Cell Research & Therapy | 2019 | 360 | 218 | |||
Navigating in vitro bioactivity data by investigating available resources using model compounds | Scientific Data | 2019 | 327 | 21 | |||
Fate of systemically and locally administered adipose-derived mesenchymal stromal cells and their effect on wound healing | Stem Cells Translational Medicine | 2019 | 303 | 236 | |||
Poly-Lactic Acid-Based Biopolymer Formulations Are Safe for Sustained Intratympanic Dexamethasone Delivery | Otology & Neurotology | 2019 | 357 | 0 | |||
Optimizing synthetic miRNA minigene architecture for efficient miRNA hairpin concatenation and multi-target gene knockdown | Molecular Therapy - Nucleic Acids | 2019 | 409 | 204 | |||
Implementation research for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva infection prevention and control (IPC)-think tank (part 1) | Antimicrobial Resistance and Infection Control | 2019 | 365 | 191 | |||
Generation of human induced pluripotent stem cell line UNIGEi001-A from a 2-years old patient with Mucopolysaccharidosis type IH disease | Stem Cell Research | 2019 | 347 | 166 | |||
Technology for the prevention of antimicrobial resistance and healthcare-associated infections; 2017 Geneva IPC-Think Tank (Part 2) | Antimicrobial Resistance and Infection Control | 2019 | 388 | 158 | |||
NADPH oxidase 4 regulates inflammation in ischemic heart failure: role of soluble epoxide hydrolase | Antioxidants & Redox Signaling | 2019 | 321 | 1 | |||
Pharmacological characterization of the seven human NOX isoforms and their inhibitors | Redox Biology | 2019 | 371 | 318 | |||
Broadening the infection prevention and control network globally; 2017 Geneva IPC-think tank (part 3) | Antimicrobial Resistance and Infection Control | 2019 | 366 | 162 | |||
Viral chimeras decrypt the role of enterovirus capsid proteins in viral tropism, acid sensitivity and optimal growth temperature | PLOS Pathogens | 2018 | 494 | 258 | |||
GROW: a model for mentorship to advance women's leadership in global health | Global Health, Epidemiology and Genomics | 2018 | 380 | 171 | |||
Altered Humoral Immune Responses and IgG Subtypes in NOX2-Deficient Mice and Patients: A Key Role for NOX2 in Antigen-Presenting Cells | Frontiers in Immunology | 2018 | 441 | 219 | |||
Decreased neural precursor cell pool in NADPH oxidase 2-deficiency: From mouse brain to neural differentiation of patient derived iPSC | Redox Biology | 2017 | 473 | 179 | |||
Transcription factor NRF2 controls the fate of neural stem cells in the subgranular zone of the hippocampus | Redox Biology | 2017 | 447 | 177 | |||
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) | Redox Biology | 2017 | 542 | 697 | |||
Decreased NOX2 expression in the brain of patients with bipolar disorder: association with valproic acid prescription and substance abuse | Translational Psychiatry | 2017 | 594 | 181 | |||
Comparison of 2D and 3D neural induction methods for the generation of neural progenitor cells from human induced pluripotent stem cells | Stem Cell Research | 2017 | 485 | 245 | |||
NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence? | Free Radical Biology & Medicine | 2017 | 420 | 202 | |||
Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma | Cancer Cell | 2017 | 467 | 5 | |||
Fingerprinting of neurotoxic compounds using a mouse embryonic stem cell dual luminescence reporter assay | Archives of toxicology | 2017 | 653 | 455 | |||
Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis | Free radical biology & medicine | 2016 | 635 | 249 | |||
Staphylococcus aureus, phagocyte NADPH oxidase and chronic granulomatous disease | FEMS microbiology reviews | 2016 | 551 | 3 | |||
NADPH oxidase 4 deficiency increases tubular cell death during acute ischemic reperfusion injury | Scientific Reports | 2016 | 580 | 198 | |||
NADPH oxidase 4 deficiency leads to impaired wound repair and reduced dityrosine-crosslinking, but does not affect myofibroblast formation | Free radical biology & medicine | 2016 | 488 | 287 | |||
A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC) | Lab on a chip | 2016 | 889 | 1,321 | |||
A subset of N-substituted phenothiazines inhibits NADPH oxidases | Free radical biology & medicine | 2015 | 557 | 527 | |||
Lentivector Knockdown of CCR5 in Hematopoietic Stem and Progenitor Cells Confers Functional and Persistent HIV-1 Resistance in Humanized Mice | Journal of virology | 2015 | 626 | 375 | |||
Phagocyte NADPH oxidase and specific immunity | Clinical science | 2015 | 612 | 2 | |||
Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways | Journal of pathology | 2015 | 906 | 335 | |||
NOX3-Targeted therapies for inner ear pathologies | Current pharmaceutical design | 2015 | 555 | 4 | |||
Voltage-Gated Proton Channels as Novel Drug Targets: From NADPH Oxidase Regulation to Sperm Biology | Antioxidants & redox signaling | 2015 | 651 | 0 | |||
Human three-dimensional engineered neural tissue reveals cellular and molecular events following cytomegalovirus infection | Biomaterials | 2015 | 799 | 8 | |||
Reactive Oxygen-Related Diseases: Therapeutic Targets and Emerging Clinical Indications | Antioxidants & redox signaling | 2015 | 515 | 376 | |||
NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of Acute Respiratory Distress Syndrome | International journal of clinical and experimental pathology | 2014 | 636 | 3 | |||
Profiling of drugs and environmental chemicals for functional impairment of neural crest migration in a novel stem cell-based test battery | Archives of toxicology | 2014 | 467 | 209 | |||
Comprehensive metagenomic analysis of glioblastoma reveals absence of known virus despite antiviral-like type I interferon gene response | International journal of cancer | 2014 | 693 | 390 | |||
Transplantation cellulaire : traitements actuels et perspectives d'avenir | Revue médicale suisse | 2014 | 854 | 14 | |||
Engineering of midbrain organoids containing long-lived dopaminergic neurons | Stem cells and development | 2014 | 704 | 881 | |||
Bacillus calmette-guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation | PLOS pathogens | 2014 | 788 | 276 | |||
Screening of bioactive peptides using an embryonic stem cell-based neurodifferentiation assay | The AAPS journal | 2014 | 559 | 215 | |||
Optimized Generation of Functional Neutrophils and Macrophages from Patient-Specific Induced Pluripotent Stem Cells: Ex Vivo Models of X(0)-Linked, AR22(0)- and AR47(0)- Chronic Granulomatous Diseases | BioResearch open access | 2014 | 535 | 578 | |||
HIV-1 Tat C modulates NOX2 and NOX4 expressions through miR-17 in a human microglial cell line | Journal of neurochemistry | 2014 | 477 | 472 | |||
Optimization of Critical Hairpin Features Allows miRNA-based Gene Knockdown Upon Single-copy Transduction | Molecular therapy. Nucleic acids | 2014 | 524 | 212 | |||
The NADPH oxidase Nox2 regulates VEGFR1/CSF-1R-mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex | GLIA | 2013 | 616 | 1 | |||
Quinone compounds regulate the level of ROS production by the NADPH oxidase Nox4 | Biochemical pharmacology | 2013 | 831 | 1 | |||
Molecular imaging reveals rapid reduction of endothelial activation in early atherosclerosis with apocynin independent of antioxidative properties | Arteriosclerosis, thrombosis, and vascular biology | 2013 | 618 | 0 | |||
Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress | Antioxidants & redox signaling | 2013 | 619 | 1 | |||
The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma | Biomaterials | 2013 | 674 | 6 | |||
Evolution of the ferric reductase domain (FRD) superfamily: modularity, functional diversification, and signature motifs | PloS one | 2013 | 580 | 333 | |||
Test systems of developmental toxicity: state-of-the art and future perspectives | Archives of toxicology | 2013 | 559 | 2 | |||
The role of immunosuppression in the transplantation of allogenic neural precursors derived from human pluripotent stem cells for Parkinson's disease | Stem cell research & therapy | 2013 | 922 | 282 | |||
Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury | Journal of Molecular and Cellular Cardiology | 2013 | 596 | 0 | |||
Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach | Archives of toxicology | 2013 | 669 | 1,247 | |||
Embryonic stem cell-based screen for small molecules: cluster analysis reveals four response patterns in developing neural cells | Current medicinal chemistry | 2013 | 671 | 0 | |||
Monocrotophos in Gandaman village: India school lunch deaths and need for improved toxicity testing | Archives of toxicology | 2013 | 520 | 150 | |||
NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion | Diabetes | 2012 | 751 | 476 | |||
Diabetes, comorbidities and increased long-term mortality in older patients admitted for geriatric inpatient care | Diabetes & metabolism | 2012 | 663 | 0 | |||
NADPH-oxidase 4 protects against kidney fibrosis during chronic renal injury | Journal of the American Society of Nephrology | 2012 | 519 | 0 | |||
Cellular diversity within embryonic stem cells: pluripotent clonal sublines show distinct differentiation potential | Journal of Cellular and Molecular Medicine | 2012 | 694 | 4 | |||
Telomere length, comorbidity, functional, nutritional and cognitive status as predictors of 5 years post hospital discharge survival in the oldest old | The Journal of nutrition, health & aging | 2012 | 598 | 68 | |||
Reactive oxygen species: from health to disease | Schweizerische medizinische Wochenschrift | 2012 | 4,451 | 2,814 | |||
NADPH oxidase elevations in pyramidal neurons drive psychosocial stress-induced neuropathology | Translational psychiatry | 2012 | 583 | 380 | |||
Targeting NOX enzymes in the central nervous system: therapeutic opportunities | Cellular and molecular life sciences | 2012 | 567 | 362 | |||
Hyperinflammation of chronic granulomatous disease is abolished by NOX2 reconstitution in macrophages and dendritic cells | Journal of pathology | 2012 | 629 | 3 | |||
Detection of reactive oxygen species derived from the family of NOX NADPH oxidases | Free radical biology & medicine | 2012 | 669 | 2 | |||
Extensive natural variation for cellular hydrogen peroxide release is genetically controlled | PloS one | 2012 | 696 | 383 | |||
Haplotype-based banking of human pluripotent stem cells for transplantation: potential and limitations | Stem cells and development | 2012 | 640 | 711 | |||
The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network | Cell death and differentiation | 2012 | 656 | 329 | |||
Generation and applications of human pluripotent stem cells induced into neural lineages and neural tissues | Frontiers in physiology | 2012 | 620 | 810 | |||
Activation of TRPC6 channels is essential for lung ischaemia-reperfusion induced oedema in mice | Nature communications | 2012 | 670 | 466 | |||
Deficiency in the NADPH oxidase 4 predisposes towards diet-induced obesity | International journal of obesity | 2012 | 689 | 5 | |||
Prospective comparison of 6 comorbidity indices as predictors of 1-year post-hospital discharge institutionalization, readmission, and mortality in elderly individuals | Journal of the American Medical Directors Association | 2012 | 571 | 0 | |||
A key role for NOX4 in epithelial cell death during development of lung fibrosis | Antioxidants & redox signaling | 2011 | 730 | 5 | |||
High levels of comorbidity and disability cancel out the dementia effect in predictions of long-term mortality after discharge in the very old | Dementia and geriatric cognitive disorders | 2011 | 619 | 4 | |||
Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation | Cell death and differentiation | 2011 | 592 | 0 | |||
NOX-4 is expressed in thickened pulmonary arteries in idiopathic pulmonary fibrosis | Nature medicine | 2011 | 536 | 1 | |||
NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action | British journal of pharmacology | 2011 | 696 | 0 | |||
Production of the plasma-cell survival factor a proliferation-inducing ligand (APRIL) peaks in myeloid precursor cells from human bone marrow | Blood | 2011 | 658 | 1 | |||
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism | PloS one | 2011 | 681 | 363 | |||
Mild cognitive impairment, degenerative and vascular dementia as predictors of intra-hospital, short- and long-term mortality in the oldest old | Aging Clinical and Experimental Research | 2011 | 649 | 41 | |||
TNF-α blockade in chronic granulomatous disease-induced hyperinflammation: patient analysis and murine model | Journal of allergy and clinical immunology | 2011 | 530 | 0 | |||
NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon | Molecular and cellular biology | 2010 | 600 | 0 | |||
Increased brain damage after ischaemic stroke in mice lacking the chemokine receptor CCR5 | British journal of pharmacology | 2010 | 777 | 1 | |||
The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses | The Journal of neuroscience | 2010 | 601 | 1 | |||
Markers of murine embryonic and neural stem cells, neurons and astrocytes: reference points for developmental neurotoxicity testing | Alternatives to animal experimentation | 2010 | 472 | 0 | |||
Prospective comparison of six co-morbidity indices as predictors of 5 years post hospital discharge survival in the elderly | Rejuvenation research | 2010 | 585 | 2 | |||
Geriatrics index of comorbidity was the most accurate predictor of death in geriatric hospital among six comorbidity scores | Journal of clinical epidemiology | 2010 | 727 | 0 | |||
Nicotinamide adenine dinucleotide phosphate reduced oxidase 5 (Nox5) regulation by angiotensin II and endothelin-1 is mediated via calcium/calmodulin-dependent, rac-1-independent pathways in human endothelial cells | Circulation research | 2010 | 562 | 0 | |||
Telomere length is not predictive of dementia or MCI conversion in the oldest old | Neurobiology of aging | 2010 | 613 | 0 | |||
Calnexin deficiency leads to dysmyelination | The Journal of biological chemistry | 2010 | 558 | 0 | |||
Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries | Circulation | 2010 | 608 | 0 | |||
Invasive microsporidiosis in allogeneic haematopoietic SCT recipients | Bone marrow transplantation | 2010 | 537 | 0 | |||
Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death | Experimental cell research | 2010 | 509 | 0 | |||
Telomere length and ApoE polymorphism in mild cognitive impairment, degenerative and vascular dementia | Journal of the neurological sciences | 2010 | 635 | 1 | |||
Dissemination of intraperitoneal ovarian cancer: Discussion of mechanisms and demonstration of lymphatic spreading in ovarian cancer model | Critical reviews in oncology/hematology | 2009 | 686 | 1 | |||
NOX4 expression in human microglia leads to constitutive generation of reactive oxygen species and to constitutive IL-6 expression | Journal of innate immunity | 2009 | 645 | 4 | |||
Involvement of NOX2 in the development of behavioral and pathologic alterations in isolated rats | Biological psychiatry | 2009 | 639 | 0 | |||
Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation | Human mutation | 2009 | 615 | 0 | |||
Distinct roles of BARD1 isoforms in mitosis: full-length BARD1 mediates Aurora B degradation, cancer-associated BARD1beta scaffolds Aurora B and BRCA2 | Cancer research | 2009 | 523 | 1 | |||
NOX enzymes in the central nervous system: from signaling to disease | Antioxidants & redox signaling | 2009 | 584 | 0 | |||
Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation | Arteriosclerosis, thrombosis, and vascular biology | 2009 | 637 | 436 | |||
Does dementia predict adverse hospitalization outcomes? A prospective study in aged inpatients | International journal of geriatric psychiatry | 2009 | 533 | 0 | |||
Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | Antioxidants & redox signaling | 2009 | 622 | 2 | |||
NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice | American journal of respiratory and critical care medicine | 2009 | 678 | 0 | |||
Neural progenitors derived from human embryonic stem cells are targeted by allogeneic T and natural killer cells | Journal of Cellular and Molecular Medicine | 2009 | 555 | 96 | |||
NADPH oxidase 1 deficiency alters caveolin phosphorylation and angiotensin II-receptor localization in vascular smooth muscle | Antioxidants & redox signaling | 2009 | 534 | 0 | |||
Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture | Stem cells | 2009 | 604 | 5 | |||
Pluripotent stem cells as new drugs? The example of Parkinson's disease | International journal of pharmaceutics | 2009 | 700 | 3 | |||
A Sox1 to Pax6 switch drives neuroectoderm to radial glia progression during differentiation of mouse embryonic stem cells | Stem cells | 2009 | 609 | 2 | |||
Phenazopyridine induces and synchronizes neuronal differentiation of embryonic stem cells | Journal of Cellular and Molecular Medicine | 2009 | 654 | 87 | |||
Demented versus non-demented very old inpatients: the same comorbidities but poorer functional and nutritional status | Age and ageing | 2008 | 687 | 207 | |||
NOX family NADPH oxidases in liver and in pancreatic islets: a role in the metabolic syndrome and diabetes? | Biochemical Society transactions | 2008 | 566 | 0 | |||
Neural commitment of embryonic stem cells: molecules, pathways and potential for cell therapy | Journal of pathology | 2008 | 605 | 6 | |||
NOX enzymes as novel targets for drug development | Seminars in immunopathology | 2008 | 593 | 1 | |||
Branched fungal beta-glucan causes hyperinflammation and necrosis in phagocyte NADPH oxidase-deficient mice | Journal of pathology | 2008 | 597 | 5 | |||
Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development | American journal of human genetics | 2008 | 618 | 528 | |||
Regulation of NOX1 expression by GATA, HNF-1alpha, and Cdx transcription factors | Free radical biology & medicine | 2008 | 613 | 0 | |||
The NADPH oxidase NOX2 plays a role in periodontal pathologies | Seminars in immunopathology | 2008 | 610 | 344 | |||
NOX enzymes in immuno-inflammatory pathologies | Seminars in immunopathology | 2008 | 577 | 204 | |||
The biological and ethical basis of the use of human embryonic stem cells for in vitro test systems or cell therapy | Alternatives to animal experimentation | 2008 | 515 | 0 | |||
Hyperinflammation in chronic granulomatous disease and anti-inflammatory role of the phagocyte NADPH oxidase | Seminars in immunopathology | 2008 | 615 | 363 | |||
Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase | The Journal of neuroscience | 2008 | 600 | 0 | |||
A pure population of ectodermal cells derived from human embryonic stem cells | Stem cells | 2008 | 646 | 0 | |||
Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells | Arteriosclerosis, thrombosis, and vascular biology | 2007 | 570 | 0 | |||
Aging: a revisited theory based on free radicals generated by NOX family NADPH oxidases | Experimental gerontology | 2007 | 531 | 0 | |||
The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology | Physiological reviews | 2007 | 1,332 | 0 | |||
NOX4 activity is determined by mRNA levels and reveals a unique pattern of ROS generation | Biochemical journal | 2007 | 626 | 0 | |||
Expression and function of alpha-smooth muscle actin during embryonic-stem-cell-derived cardiomyocyte differentiation | Journal of cell science | 2007 | 593 | 360 | |||
Genetic engineering of embryonic stem cells | Schweizerische medizinische Wochenschrift | 2007 | 458 | 0 | |||
Fetal bovine serum enables cardiac differentiation of human embryonic stem cells | Differentiation | 2007 | 589 | 1 | |||
NOX5 is expressed at the plasma membrane and generates superoxide in response to protein kinase C activation | Biochimie | 2007 | 647 | 0 | |||
NOX1 deficiency protects from aortic dissection in response to angiotensin II | Hypertension | 2007 | 590 | 0 | |||
NOX family NADPH oxidases: not just in mammals | Biochimie | 2007 | 800 | 0 | |||
Embryonic and adult stem cell-derived cardiomyocytes: lessons from in vitro models | Reviews of physiology, biochemistry and pharmacology | 2006 | 578 | 0 | |||
Decreased blood pressure in NOX1-deficient mice | FEBS letters | 2006 | 527 | 0 | |||
Response letter to Christ-Crain and Mueller (J Am Geriatr Soc. 2005, PMID: 16551331) | Journal of the American Geriatrics Society | 2006 | 440 | 1 | |||
Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors | Stem cells | 2006 | 561 | 0 | |||
Response letter to Tan and Lim (J Am Geriatr Soc. 2005, PMID: 16551330) | Journal of the American Geriatrics Society | 2006 | 490 | 1 | |||
The NADPH oxidase NOX4 drives cardiac differentiation: Role in regulating cardiac transcription factors and MAP kinase activation | Molecular biology of the cell | 2006 | 568 | 0 | |||
Genetic engineering of embryonic stem cells | Schweizerische medizinische Wochenschrift | 2006 | 449 | 0 | |||
Pax6-induced alteration of cell fate: shape changes, expression of neuronal alpha tubulin, postmitotic phenotype, and cell migration | Journal of neurobiology | 2006 | 543 | 0 | |||
Microcebus murinus: a useful primate model for human cerebral aging and Alzheimer's disease? | Genes, brain and behavior | 2006 | 610 | 1 | |||
A key role for the microglial NADPH oxidase in APP-dependent killing of neurons | Neurobiology of aging | 2006 | 600 | 1 | |||
Aberrant expression of BARD1 in breast and ovarian cancers with poor prognosis | International journal of cancer | 2006 | 568 | 0 | |||
Expression of mRNA for ROS-generating NADPH oxidases in the aging stomach | Experimental gerontology | 2005 | 584 | 0 | |||
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase | Oncogene | 2005 | 565 | 0 | |||
Expression of NOX1, a superoxide-generating NADPH oxidase, in colon cancer and inflammatory bowel disease | Journal of pathology | 2005 | 579 | 0 | |||
Cellules souches embryonnaires : après l'enthousiasme de la campagne, les défis de la clinique | Revue médicale suisse | 2005 | 465 | 0 | |||
Chemokine receptors in the central nervous system: role in brain inflammation and neurodegenerative diseases | Journal of neuroimmunology | 2005 | 1,000 | 0 | |||
Expression and activity of NOX5 in the circulating malignant B cells of hairy cell leukemia | The Journal of immunology | 2005 | 525 | 0 | |||
Procalcitonin and infection in elderly patients | Journal of the American Geriatrics Society | 2005 | 508 | 0 | |||
Spécificités des infections chez le sujet âgé | Praxis | 2004 | 568 | 0 | |||
Tissue distribution and putative physiological function of NOX family NADPH oxidases | Japanese journal of infectious diseases | 2004 | 481 | 0 | |||
NOX3, a superoxide-generating NADPH oxidase of the inner ear | The Journal of biological chemistry | 2004 | 629 | 0 | |||
Pneumonia in the very old | Lancet. Infectious diseases | 2004 | 545 | 0 | |||
Cerebrospinal fluid tau and Abeta42 concentrations in healthy subjects: delineation of reference intervals and their limitations | Clinical chemistry and laboratory medicine | 2004 | 530 | 0 | |||
Mechanism of Ca2+ activation of the NADPH oxidase 5 (NOX5) | The Journal of biological chemistry | 2004 | 502 | 2 | |||
Aging and infectious diseases in the developing world | Clinical infectious diseases | 2004 | 625 | 0 | |||
Nuclear-cytoplasmic translocation of BARD1 is linked to its apoptotic activity | Oncogene | 2004 | 491 | 0 | |||
BARD1 expression during spermatogenesis is associated with apoptosis and hormonally regulated | Biology of reproduction | 2004 | 414 | 0 | |||
Chemokine-induced cell death in CCR5-expressing neuroblastoma cells | Journal of neuroimmunology | 2003 | 489 | 0 | |||
Two novel proteins activate superoxide generation by the NADPH oxidase NOX1 | The Journal of biological chemistry | 2003 | 578 | 0 | |||
A role for NOX NADPH oxidases in Alzheimer's disease and other types of dementia? | IUBMB life | 2003 | 579 | 0 | |||
Successful treatment of disseminated tuberculosis and acquired immunodeficiency syndrome in an 81-y-old woman | Scandinavian journal of infectious diseases | 2003 | 607 | 0 | |||
NOX family NADPH oxidases: do they have built-in proton channels? | The Journal of general physiology | 2002 | 435 | 0 | |||
Nanoscale liquid chromatography and capillary electrophoresis coupled to electrospray mass spectrometry for the detection of amyloid-β peptide related to alzheimer's disease | Journal of chromatography | 2002 | 610 | 0 | |||
Nanoscale liquid chromatography and capillary electrophoresis coupled to electrospray mass spectrometry for the detection of amyloid-β peptide related to Alzheimer’s disease | Journal of chromatography | 2002 | 29 | 0 | |||
Ageing and infection | Lancet. Infectious diseases | 2002 | 504 | 0 | |||
Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum | The Journal of biological chemistry | 2002 | 501 | 0 | |||
Expression of an alpha7 duplicate nicotinic acetylcholine receptor-related protein in human leukocytes | Journal of neuroimmunology | 2002 | 520 | 0 | |||
The HIV-1 Nef protein and phagocyte NADPH oxidase activation | The Journal of biological chemistry | 2002 | 500 | 0 | |||
The PDZ-interacting domain of TRPC4 controls its localization and surface expression in HEK293 cells | Journal of cell science | 2002 | 534 | 187 | |||
Calreticulin reveals a critical Ca(2+) checkpoint in cardiac myofibrillogenesis | The Journal of cell biology | 2002 | 551 | 0 | |||
Geneva Biology of Ageing Workshop 2000: phagocytes, inflammation, and ageing | Experimental gerontology | 2001 | 517 | 0 | |||
Identification of BARD1 as mediator between proapoptotic stress and p53-dependent apoptosis | Molecular cell | 2001 | 622 | 0 | |||
Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors | FEBS letters | 2001 | 575 | 0 | |||
Plaidoyer pour un centre de recherche sur le vieillissement à Genève | Médecine et hygiène | 2001 | 521 | 0 | |||
A Ca(2+)-activated NADPH oxidase in testis, spleen, and lymph nodes | The Journal of biological chemistry | 2001 | 603 | 0 | |||
Functional specialization of calreticulin domains | The Journal of cell biology | 2001 | 566 | 0 | |||
Heme histidine ligands within gp91(phox) modulate proton conduction by the phagocyte NADPH oxidase | The Journal of biological chemistry | 2001 | 580 | 0 | |||
Is Staphylococcus aureus an intracellular pathogen? | Trends in microbiology | 2000 | 498 | 0 | |||
Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 524 | 0 | |||
Professional phagocytes: predators and prey of microorganisms | Schweizerische medizinische Wochenschrift | 2000 | 522 | 0 | |||
Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells | Infection and immunity | 2000 | 567 | 0 | |||
Selective inhibition of IgG-mediated phagocytosis in gelsolin-deficient murine neutrophils | The Journal of immunology | 2000 | 528 | 0 | |||
A mammalian H+ channel generated through alternative splicing of the NADPH oxidase homolog NOH-1 | Science | 2000 | 621 | 0 | |||
Fibronectin-binding protein acts as Staphylococcus aureus invasin via fibronectin bridging to integrin alpha5beta1 | Cellular microbiology | 1999 | 638 | 0 | |||
Calreticulin is essential for cardiac development | The Journal of cell biology | 1999 | 571 | 0 | |||
Localization of intracellular Ca2+ stores in HeLa cells during infection with Chlamydia trachomatis | Journal of cell science | 1999 | 432 | 187 | |||
Ca2+ regulation of interactions between endoplasmic reticulum chaperones | The Journal of biological chemistry | 1999 | 499 | 0 | |||
A novel H(+) conductance in eosinophils: unique characteristics and absence in chronic granulomatous disease | The Journal of experimental medicine | 1999 | 524 | 0 | |||
The HIV Nef protein alters Ca(2+) signaling in myelomonocytic cells through SH3-mediated protein-protein interactions | The Journal of biological chemistry | 1999 | 601 | 0 | |||
Vitronectin interaction with glycosaminoglycans. Kinetics, structural determinants, and role in binding to endothelial cells | The Journal of biological chemistry | 1999 | 562 | 0 | |||
Ca2+-induced exocytosis in individual human neutrophils: high- and low-affinity granule populations and submaximal responses | EMBO journal | 1998 | 546 | 0 | |||
Electron currents generated by the human phagocyte NADPH oxidase | Nature | 1998 | 503 | 0 | |||
Aerolysin induces G-protein activation and Ca2+ release from intracellular stores in human granulocytes | The Journal of biological chemistry | 1998 | 585 | 0 | |||
Store-operated Ca2+ influx and stimulation of exocytosis in HL-60 granulocytes | The Journal of biological chemistry | 1997 | 572 | 0 | |||
Chemoattractant-induced respiratory burst: increases in cytosolic Ca2+ concentrations are essential and synergize with a kinetically distinct second signal | Biochemical journal | 1997 | 560 | 0 | |||
Nef-mediated clathrin-coated pit formation | The Journal of cell biology | 1997 | 537 | 0 | |||
European workshop on the cell biology of phagocytes | Journal of leukocyte biology | 1997 | 529 | 0 | |||
Second-messenger regulation of receptor association with clathrin-coated pits: a novel and selective mechanism in the control of CD4 endocytosis | Molecular biology of the cell | 1997 | 533 | 0 | |||
Calreticulin | Cell | 1997 | 503 | 0 | |||
Highly supralinear feedback inhibition of Ca2+ uptake by the Ca2+ load of intracellular stores | The Journal of biological chemistry | 1996 | 600 | 0 | |||
Proton currents in human eosinophils | The American journal of physiology | 1996 | 459 | 0 | |||
Store-operated Ca2+ influx: what is the message from the stores to the membrane? | The Journal of laboratory and clinical medicine | 1996 | 559 | 0 | |||
Organization of Ca2+ stores in myeloid cells: association of SERCA2b and the type-1 inositol-1,4,5-trisphosphate receptor | Biochemical journal | 1996 | 471 | 0 | |||
Calreticulin: how many functions in how many cellular compartments? Como, April 1996 | Cell calcium | 1996 | 492 | 0 | |||
Overexpression of calreticulin increases intracellular Ca2+ storage and decreases store-operated Ca2+ influx | The Journal of biological chemistry | 1996 | 532 | 0 | |||
Highly cooperative Ca2+ elevations in response to Ins(1,4,5)P3 microperfusion through a patch-clamp pipette | Biophysical journal | 1995 | 589 | 0 | |||
CD4 in nonlymphocytic cells: more than an HIV receptor? | The Journal of laboratory and clinical medicine | 1995 | 505 | 0 | |||
Caracterisation de l'influx Ca2+ dans les neutrophiles humains par la technique du patch clamp | Schweizerische medizinische Wochenschrift | 1995 | 539 | 0 | |||
Intracellular pattern of cytosolic Ca2+ changes during adhesion and multiple phagocytosis in human neutrophils. Dynamics of intracellular Ca2+ stores | Blood | 1995 | 536 | 0 | |||
Redistribution of intracellular Ca2+ stores during phagocytosis in human neutrophils | Science | 1994 | 506 | 2 | |||
Combination of microfluorimetric monitoring of cytosolic calcium and pH with patch clamp electrophysiological recordings in neutrophil granulocytes | Methods in enzymology | 1994 | 537 | 0 | |||
Rapid heparin-sensitive Ca2+ release following Ca(2+)-ATPase inhibition in intact HL-60 granulocytes. Evidence for Ins(1,4,5)P3-dependent Ca2+ cycling across the membrane of Ca2+ stores | Biochemical journal | 1994 | 589 | 0 | |||
Characterization of receptor-mediated and store-regulated Ca2+ influx in human neutrophils | Biochemical journal | 1994 | 548 | 0 | |||
Highly co-operative Ca2+ activation of intermediate-conductance K+ channels in granulocytes from a human cell line | Journal of physiology | 1993 | 488 | 0 | |||
Proton channels, plasma membrane potential, and respiratory burst in human neutrophils | European journal of haematology | 1993 | 651 | 0 | |||
Ca2+ and Mg2+ regulation of inositol 1,4,5-triphosphate binding in myeloid cells | The Journal of biological chemistry | 1993 | 553 | 0 | |||
Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C | Biochemical journal | 1993 | 537 | 0 | |||
Inositol 1,4,5-trisphosphate binding sites copurify with the putative Ca-storage protein calreticulin in rat liver | Cell calcium | 1993 | 593 | 0 | |||
The regulation of store-dependent Ca2+ influx in HL-60 granulocytes involves GTP-sensitive elements | The Journal of biological chemistry | 1993 | 510 | 0 | |||
Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells | Advances in second messenger and phosphoprotein research | 1993 | 514 | 0 | |||
Ion channels and receptor-mediated Ca2+ influx in neutrophil granulocytes | Blood cells | 1993 | 493 | 0 | |||
The calcium-binding protein calreticulin is a major constituent of lytic granules in cytolytic T lymphocytes | The Journal of experimental medicine | 1993 | 567 | 0 | |||
Proton currents in human granulocytes: regulation by membrane potential and intracellular pH | Journal of physiology | 1993 | 498 | 0 | |||
Inositol phosphates. Metabolism and site of action in neutrophil granulocytes | Advances in second messenger and phosphoprotein research | 1992 | 490 | 0 | |||
Purification of an inositol 1,4,5-trisphosphate-binding calreticulin-containing intracellular compartment of HL-60 cells | Biochemical journal | 1992 | 561 | 0 | |||
Cyclopiazonic acid depletes intracellular Ca2+ stores and activates an influx pathway for divalent cations in HL-60 cells | The Journal of biological chemistry | 1992 | 508 | 0 | |||
Differential effects on neutrophil activation of staurosporin and its protein kinase C-selective derivative cgp 41231 | European journal of pharmacology | 1992 | 611 | 0 | |||
Regulation of Ca2+ influx in myeloid cells. Role of plasma membrane potential, inositol phosphates, cytosolic free [Ca2+], and filling state of intracellular Ca2+ stores | The Journal of clinical investigation | 1992 | 609 | 0 | |||
s-cyclophilin is retained intracellularly via a unique COOH-terminal sequence and colocalizes with the calcium storage protein calreticulin | The Journal of cell biology | 1992 | 540 | 0 | |||
Thermodynamics of cation binding to rabbit skeletal muscle calsequestrin. Evidence for distinct Ca(2+)- and Mg(2+)-binding sites | The Journal of biological chemistry | 1991 | 539 | 0 | |||
Ca(2+)-storage organelles | FEBS letters | 1991 | 464 | 0 | |||
Electrophysiological properties of human neutrophils | Advances in experimental medicine and biology | 1991 | 536 | 0 | |||
The calcium signal and neutrophil activation | Clinical biochemistry | 1990 | 475 | 0 | |||
Sequence similarity of calreticulin with a Ca2(+)-binding protein that co-purifies with an Ins(1,4,5)P3-sensitive Ca2+ store in HL-60 cells | Biochemical journal | 1990 | 526 | 0 | |||
Effect of cyclic adenosine monophosphate elevations on functional responses of polymorphonuclear leukocytes from patients with cystic fibrosis | Pediatric pulmonology | 1989 | 571 | 0 | |||
Calciosome, a sarcoplasmic reticulum-like organelle involved in intracellular Ca2+-handling by non-muscle cells: studies in human neutrophils and HL-60 cells | Cell calcium | 1989 | 589 | 0 | |||
"Calciosome," a cytoplasmic organelle: the inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells? | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 679 | 0 | |||
Bacterial toxins and neutrophil activation | Seminars in hematology | 1988 | 475 | 0 | |||
Immunocytological identification of the microsomal calcium store of nonmuscle cells | Journal of cardiovascular pharmacology | 1988 | 576 | 0 | |||
The Ins(1,4,5)P3-sensitive Ca2+ store of non-muscle cells: endoplasmic reticulum or calciosomes? | Journal of experimental biology | 1988 | 541 | 0 | |||
Early termination of a prospective, randomized trial comparing teicoplanin and flucloxacillin for treating severe staphylococcal infections | The Journal of infectious diseases | 1987 | 601 | 0 | |||
Control of cytosolic free calcium by intracellular organelles in bovine adrenal glomerulosa cells. Effects of sodium and inositol 1,4,5-trisphosphate | The Journal of biological chemistry | 1987 | 511 | 0 | |||
Nonselective inhibition of neutrophil functions by sphinganine | The Journal of biological chemistry | 1987 | 519 | 0 | |||
Subcellular distribution of Ca2+ pumping sites in human neutrophils | The Journal of clinical investigation | 1987 | 507 | 0 | |||
The role of cytosolic free calcium in the generation of inositol 1,4,5-trisphosphate and inositol 1,3,4-trisphosphate in HL-60 cells. Differential effects of chemotactic peptide receptor stimulation at distinct Ca2+ levels | The Journal of biological chemistry | 1986 | 533 | 0 | |||
Leukotriene B4 stimulation of phagocytes results in the formation of inositol 1,4,5-trisphosphate. A second messenger for Ca2+ mobilization | Biochemical journal | 1986 | 572 | 0 | |||
Chemotactic peptide activation of human neutrophils and HL-60 cells. Pertussis toxin reveals correlation between inositol trisphosphate generation, calcium ion transients, and cellular activation | The Journal of clinical investigation | 1985 | 586 | 0 |