UNIGE document Scientific Article
previous document  unige:75015  next document
add to browser collection
Title

The vestibular implant: frequency-dependency of the electrically evoked vestibulo-ocular reflex in humans

Authors
van de Berg, Raymond
Nguyen, T A Khoa
Stokroos, Robert
Kingma, Herman
show hidden authors show all authors [1 - 9]
Published in Frontiers in Systems Neuroscience. 2014, vol. 8, no. 255
Abstract The vestibulo-ocular reflex (VOR) shows frequency-dependent behavior. This study investigated whether the characteristics of the electrically evoked VOR (eVOR) elicited by a vestibular implant, showed the same frequency-dependency. Twelve vestibular electrodes implanted in seven patients with bilateral vestibular hypofunction (BVH) were tested. Stimuli consisted of amplitude-modulated electrical stimulation with a sinusoidal profile at frequencies of 0.5, 1, and 2 Hz. The main characteristics of the eVOR were evaluated and compared to the "natural" VOR characteristics measured in a group of age-matched healthy volunteers who were subjected to horizontal whole body rotations with equivalent sinusoidal velocity profiles at the same frequencies. A strong and significant effect of frequency was observed in the total peak eye velocity of the eVOR. This effect was similar to that observed in the "natural" VOR. Other characteristics of the (e)VOR (angle, habituation-index, and asymmetry) showed no significant frequency-dependent effect. In conclusion, this study demonstrates that, at least at the specific (limited) frequency range tested, responses elicited by a vestibular implant closely mimic the frequency-dependency of the "normal" vestibular system.
Identifiers
PMID: 25653601
Full text
Article (Published version) (12.3 MB) - public document Free access
Structures
Research group Neuroprothèses sensorielles pour la restitution de l'audition et l'équilibre (268)
Citation
(ISO format)
VAN DE BERG, Raymond et al. The vestibular implant: frequency-dependency of the electrically evoked vestibulo-ocular reflex in humans. In: Frontiers in Systems Neuroscience, 2014, vol. 8, n° 255. https://archive-ouverte.unige.ch/unige:75015

140 hits

65 downloads

Update

Deposited on : 2015-09-04

Export document
Format :
Citation style :