

Other version: http://www3.interscience.wiley.com/cgi-bin/fulltext/118887554/PDFSTART
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Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis |
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Published in | FEMS immunology and medical microbiology. 2003, vol. 35, no. 2, p. 135-140 | |
Abstract | The contribution of in vivo biofilm-forming potential of Staphylococcus aureus and Staphylococcus epidermidis was studied in an experimental model of foreign body infections. Increasing inocula (from 10(2) to 10(7) organisms) of ica-positive strains of S. aureus and S. epidermidis and their ica-negative isogenic mutants (the ica locus codes for a major polysaccharide component of biofilm) were injected into subcutaneously implanted tissue cages in guinea pigs. Surprisingly, bacterial counts and time-course of tissue cage infection by ica-positive strains of S. aureus or S. epidermidis were equivalent to those of their respective ica-negative mutants, in the locally infected fluids and on tissue-cage-inserted plastic coverslips. | |
Keywords | Animals — Biofilms — Disease Models, Animal — Foreign Bodies/ complications — Guinea Pigs — Staphylococcal Infections/ etiology — Staphylococcus aureus/ pathogenicity — Staphylococcus epidermidis/ pathogenicity | |
Identifiers | PMID: 12628549 | |
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Citation (ISO format) | FRANCOIS, Patrice et al. Lack of biofilm contribution to bacterial colonisation in an experimental model of foreign body infection by Staphylococcus aureus and Staphylococcus epidermidis. In: FEMS immunology and medical microbiology, 2003, vol. 35, n° 2, p. 135-140. https://archive-ouverte.unige.ch/unige:7232 |