Scientific article
OA Policy
English

Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection

Collection
  • Open Access - Licence nationale Springer
Publication date2010
Abstract

The purpose of this study was to determine the clinical and microbiological risk factors for treatment failure of methicillin-resistant Staphylococcus aureus (MRSA) orthopedic device-related infection (ODRI). A retrospective cohort study of patients with MRSA ODRI who were treated at Geneva University Hospitals between 2000 and 2008 was undertaken. Stored MRSA isolates were retrieved for genetic characterization and determination of the vancomycin minimum inhibitory concentration (MIC). Fifty-two patients were included, of whom 23 (44%) had joint arthroplasty and 29 (56%) had osteosynthesis. All 41 of the retrieved MRSA isolates were susceptible to vancomycin (MIC

Keywords
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents/pharmacology/ therapeutic use
  • Bacterial Typing Techniques
  • Cohort Studies
  • Female
  • Genotype
  • Humans
  • Male
  • Methicillin-Resistant Staphylococcus aureus/ isolation & purification
  • Microbial Sensitivity Tests
  • Middle Aged
  • Orthopedic Procedures/adverse effects
  • Prosthesis-Related Infections/ drug therapy
  • Retrospective Studies
  • Risk Factors
  • Staphylococcal Infections/ drug therapy/microbiology
  • Switzerland
  • Treatment Failure
  • Vancomycin/pharmacology/therapeutic use
Citation (ISO format)
FERRY, T. et al. Risk factors for treatment failure in orthopedic device-related methicillin-resistant Staphylococcus aureus infection. In: European journal of clinical microbiology & infectious diseases, 2010, vol. 29, n° 2, p. 171–180. doi: 10.1007/s10096-009-0837-y
Main files (1)
Article (Published version)
accessLevelPublic
Identifiers
ISSN of the journal0934-9723
601views
217downloads

Technical informations

Creation06/21/2010 10:24:00 AM
First validation06/21/2010 10:24:00 AM
Update time03/14/2023 3:43:29 PM
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