UNIGE document Scientific Article
previous document  unige:5126  next document
add to browser collection

An effective tool for column evaluation in the analysis of basic compounds

Stella, Cinzia
Gauvrit, Jean-Yves
Lanteri, Pierre
Published in Chimia. 2003, vol. 57, no. 4, p. 210-213
Abstract A chromatographic test is described for the evaluation of base-deactivated stationary phases. Seven test basic compounds, selected on their physico-chemical properties, were injected with two different mobile phases (one at pH 7.0 and the other at pH 3.0), on 45 chromatographic supports. Thanks to the measured chromatographic parameters (k and As), it was possible to evaluate both silanol activity and hydrophobic character of the base-deactivated columns. In addition, the validity of this chromatographic test was assessed by measuring the fundamental properties of the same supports with a general test protocol, issued from the literature.
Keywords Basic compoundsChromatographic testHigh-performance liquid chromatographyPrincipal component analysis
Full text
Article (Published version) (358 Kb) - document accessible for UNIGE members only Limited access to UNIGE
(ISO format)
STELLA, Cinzia et al. An effective tool for column evaluation in the analysis of basic compounds. In: Chimia, 2003, vol. 57, n° 4, p. 210-213. https://archive-ouverte.unige.ch/unige:5126

414 hits

0 download


Deposited on : 2010-02-09

Export document
Format :
Citation style :