PC
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study | Planta medica |  | 2017 | 630 | 4 | ||
| HDM-PAMPA to predict gastrointestinal absorption, binding percentage, equilibrium and kinetics constants with human serum albumin and using 2 end-point measurements | European journal of pharmaceutical sciences | | 2017 | 632 | 2 | ||
| Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA) | Planta medica | | 2016 | 581 | 4 | ||
| Normal phase HPLC-based activity profiling of non-polar crude plant extracts - acetylcholinesterase inhibiting guttiferones from Montrouziera cauliflora as a case study | Natural Product Research | | 2016 | 290 | 0 | ||
| Inhibition screening method of microsomal UGTs using the cocktail approach | European journal of pharmaceutical sciences | | 2015 | 633 | 0 | ||
| Modification of a PAMPA model to predict passive gastrointestinal absorption and plasma protein binding | European journal of pharmaceutical sciences | | 2015 | 636 | 0 | ||
| Computational Studies on Sirtuins from Trypanosoma cruzi: Structures, Conformations and Interactions with Phytochemicals | PLoS neglected tropical diseases |  | 2014 | 651 | 276 | ||
| Predicting both passive intestinal absorption and the dissociation constant toward albumin using the PAMPA technique | European journal of pharmaceutical sciences | | 2014 | 676 | 4 | ||
| Isolation and biological activity of compounds from Garcinia preussii | Pharmaceutical biology | | 2014 | 667 | 0 | ||
| Antifungals and acetylcholinesterase inhibitors from the stem bark of Croton heliotropiifolius | Phytochemistry letters | | 2014 | 543 | 1 | ||
| Aurones as histone deacetylase inhibitors: identification of key features | Bioorganic & medicinal chemistry letters | | 2014 | 523 | 2 | ||
| cIEF for rapid pKa determination of small molecules: A proof of concept | European journal of pharmaceutical sciences | | 2014 | 622 | 1 | ||
| Analytical Strategy to Characterize Drug–Plasma Interactions: From High Throughput to In-depth Analysis | Chimia | | 2013 | 654 | 1 | ||
| Global analytical strategy to measure drug–plasma protein interactions: from high-throughput to in-depth analysis | Drug discovery today | | 2013 | 714 | 0 | ||
| High performance affinity chromatography (HPAC) as a high-throughput screening tool in drug discovery to study drug–plasma protein interactions | Journal of pharmaceutical and biomedical analysis | | 2013 | 709 | 2 | ||
| New high throughput screening method for drug release measurements | European Journal of Pharmaceutics and Biopharmaceutics | | 2013 | 474 | 0 | ||
| Comparison of various silica-based monoliths for the analysis of large biomolecules | Journal of separation science | | 2013 | 641 | 0 | ||
| HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs? | Molecular neurodegeneration | | 2013 | 678 | 398 | ||
| Anti-inflammatory, antimicrobial and antioxidant activities of Diospyros bipindensis (Gürke) extracts and its main constituents | Journal of ethnopharmacology | | 2013 | 848 | 1 | ||
| Unsymmetrical binding modes of HOPNO inhibitor of tyrosinase: From model complexes to the enzyme | Chemistry | | 2013 | 876 | 1 | ||
| Large, chemically diverse dataset of logP measurements for benchmarking studies | European journal of pharmaceutical sciences | | 2013 | 700 | 0 | ||
| Antioxidant potential and radical scavenging effects of flavonoids from the leaves of Psidium cattleianum grown in French Polynesia | Natural product research | | 2012 | 558 | 0 | ||
| Synthesis physicochemical profile and PAMPA study of new NO-donor edaravone co-drugs | Bioorganic & medicinal chemistry | | 2012 | 614 | 0 | ||
| Characterization of drug-protein interactions by capillary electrophoresis hyphenated to mass spectrometry | Electrophoresis | | 2012 | 665 | 1 | ||
| Ultra High Pressure Liquid Chromatography for Crude Plant Extract Profiling | Journal of AOAC International | | 2011 | 738 | 7 | ||
| Biarylmethoxy isonipecotanilides as potent and selctive inhibitors of blood coagulation facture Xa | European journal of pharmaceutical sciences | | 2011 | 614 | 0 | ||
| The permeability P-glycoprotein: a focus on enantioselectivity and brain distribution | Expert opinion on drug metabolism & toxicology | | 2010 | 619 | 0 | ||
| Stereoselective block of hERG channel by bupivacaine scrutinized at molecular level | Chimia | | 2010 | 604 | 526 | ||
| Improvement of a capillary electrophoresis/frontal analysis (CE/FA) method for determining binding constants: Discussion on relevant parameters | Journal of pharmaceutical and biomedical analysis | | 2010 | 695 | 0 | ||
| Advances in LC platforms for drug discovery | Expert opinion on drug discovery | | 2010 | 657 | 0 | ||
| Stereoselective inhibition of the hERG1 potassium channel | Frontiers in pharmacology | | 2010 | 561 | 198 | ||
| Drug-protein binding: a critical review of analytical tools | Analytical & bioanalytical chemistry | | 2010 | 650 | 1,346 | ||
| Physicochemical profile and in vitro permeation behavior of a new class of non-steroidal anti-inflammatory drug candidates | European journal of pharmaceutical sciences | | 2010 | 588 | 0 | ||
| High-throughput log P determination by MEEKC coupled with UV and MS detections | Electrophoresis | | 2010 | 697 | 0 | ||
| Molecular electrocatalysis for oxygen reduction by cobalt porphyrins adsorbed at liquid/liquid interfaces | Journal of the American Chemical Society | | 2010 | 698 | 0 | ||
| In vitro blood brain barrier models as a screening tool for colloidal drug delivery systems and other nanosystems | International journal of biomedical nanoscience and nanotechnology | | 2010 | 1,134 | 1,248 | ||
| Entacapone and tolcapone, two catechol O-methyltransferase inhibitors, block fibril formation of alpha-synuclein and beta-amyloid and protect against amyloid-induced toxicity | The Journal of biological chemistry | | 2010 | 507 | 0 | ||
| Standard machine learning algorithms applied to UPLC-TOF/MS metabolic fingerprinting for the discovery of wound biomarkers in Arabidopsis thaliana | Chemometrics and intelligent laboratory systems | | 2010 | 687 | 0 | ||
| In silico tools and in vitro HTS approaches to determine lipophilicity during the drug discovery process | Hit and Lead Profiling | 2009 | 534 | 0 | |||
| Rapid log P determination of natural products in crude plant extracts from UHPLC-TOF-MS profiling data - an additional parameter for dereplication and bioavailability | Planta medica | | 2009 | 671 | 367 | ||
| Antioxidant Phenylethanoid Glycosides and a Neolignan from Jacaranda caucana | Journal of natural products | | 2009 | 609 | 0 | ||
| QSAR analysis and molecular modeling of ABCG2-specific inhibitors | Advanced drug delivery reviews | | 2009 | 621 | 0 | ||
| A 3D linear solvation energy model to quantify the affinity of flavonoid derivatives toward P-glycoprotein | European journal of pharmaceutical sciences | | 2009 | 647 | 6 | ||
| Lipophilicity determination of highly lipophilic compounds by liquid chromatography | Chemistry & biodiversity | | 2009 | 561 | 2 | ||
| Antioxidant profiling of new chemical entities from synthetic and natural origin | Planta medica | 2009 | 555 | 0 | |||
| Olive phenols efficiently inhibit the oxidation of serum albumin-bound linoleic acid and butyrylcholine esterase | Biochimica et biophysica acta. G, General subjects | | 2009 | 611 | 0 | ||
| A fast screening strategy for characterizing peptide delivery by transdermal iontophoresis | Journal of controlled release | | 2009 | 706 | 4 | ||
| Lipophilicity of basic drugs measured by hydrophilic interaction chromatography | Journal of medicinal chemistry | | 2009 | 655 | 0 | ||
| Monoamine oxidase inhibition by Rhodiola rosea L. roots | Journal of ethnopharmacology | | 2009 | 754 | 3 | ||
| Metabolite profiling of plant extracts by ultra-high-pressure liquid chromatography at elevated temperature coupled to time-of-flight mass spectrometry | Journal of chromatography | | 2009 | 618 | 0 | ||
| Fast log P determination by ultra-high-pressure liquid chromatography coupled with UV and mass spectrometry detections | Analytical & bioanalytical chemistry | | 2009 | 751 | 337 | ||
| Breast cancer resistance protein (BCRP/ABCG2): new inhibitors and QSAR studies by a 3D linear solvation energy approach | European journal of pharmaceutical sciences | | 2009 | 831 | 0 | ||
| Edaravone derivatives containing NO-donor functions | Journal of medicinal chemistry | | 2009 | 608 | 0 | ||
| Analytical tools for the physicochemical profiling of drug candidates to predict absorption/distribution | Analytical & bioanalytical chemistry | | 2009 | 703 | 483 | ||
| Optimized liquid chromatography-mass spectrometry approach for the isolation of minor stress biomarkers in plant extracts and their identification by capillary nuclear magnetic resonance | Journal of chromatography | | 2008 | 742 | 0 | ||
| High-throughput log P determination by ultraperformance liquid chromatography: a convenient tool for medicinal chemists | Journal of medicinal chemistry | | 2008 | 633 | 1 | ||
| Covalent modifications of antitetanus F(ab')2 fragments with natural and synthetic polyamines and their effects on the antibody endocytosis in cultured HL60 cells | Bioconjugate chemistry | | 2008 | 617 | 0 | ||
| Stereoselective block of hERG channel by (S)-methadone and QT interval prolongation in CYP2B6 slow metabolizer: Evidence of a safer cardiac profile of (R)-methadone | Pharmacopsychiatry | | 2008 | 669 | 0 | ||
| Chromatographic approaches for measuring log P | Molecular drug properties: measurement and prediction | 2008 | 670 | 0 | |||
| The PAMPA technique as a HTS tool for partition coefficients determination in different solvent/water systems | European journal of pharmaceutical sciences | | 2008 | 688 | 5 | ||
| Structure-antioxidant activity relationships in a series of NO-donor phenols | ChemMedChem | | 2008 | 658 | 0 | ||
| Xanthones from Gentianella amarella ssp. acuta with acetylcholinesterase and monoamine oxidase inhibitory activities | Journal of natural products | | 2008 | 543 | 0 | ||
| In vitro screening assays to identify natural or synthetic acetylcholinesterase inhibitors: thin layer chromatography versus microplate methods | European journal of pharmaceutical sciences | | 2008 | 728 | 0 | ||
| Physicochemical Profiling of Sartans: Detailed Study of Ionisation Constants and Distribution Coefficients | Helvetica chimica acta | | 2008 | 644 | 0 | ||
| Antimitotic and antiproliferative activities of chalcones: forward structure-activity relationship | Journal of medicinal chemistry | | 2008 | 661 | 0 | ||
| High throughput UV method for the estimation of thermodynamic solubility and the determination of the solubility in biorelevant media | European journal of pharmaceutical sciences | | 2008 | 627 | 0 | ||
| Highlights of Analytical Chemistry in Switzerland: Plant Metabolomics – Strategies for Biomarker Detection, Isolation, and Identification | Chimia | 2008 | 718 | 0 | |||
| Antioxidant C-Glucosylxanthones from the leaves of Arrabidaea patellifera (Bignoniaceae) | Journal of natural products | | 2008 | 570 | 0 | ||
| Isolation and quantification by high-performance liquid chromatography-ion-trap mass spectrometry of androgen sulfoconjugates in human urine | Journal of chromatography | | 2008 | 546 | 2 | ||
| UPLC-TOF-MS for plant metabolomics. A powerful tool for discriminating stress states in plants and detecting low level wound-biomarkers | American laboratory | 2008 | 606 | 0 | |||
| UPLC-TOF-MS for plant metabolomics: a sequential approach for wound marker analysis in Arabidopsis thaliana | Journal of chromatography. B | | 2008 | 671 | 0 | ||
| Inhibition of monoamine oxidase and acetylcholinesterase by Rhodiola rosea L | Planta medica | 2008 | 604 | 0 | |||
| In silico and in vitro filters for the fast estimation of skin permeation and distribution of new chemical entities | Journal of medicinal chemistry | | 2007 | 618 | 3 | ||
| Physicochemical Models for Drug Absorption | European School of Medicinal Chemistry : XXVII Advanced Course of Medicinal Chemistry | | 2007 | 133 | 52 | ||
| Development of a two-step screening ESI-TOF-MS method for rapid determination of significant stress-induced metabolome modifications in plant leaf extracts: the wound response in Arabidopsis thaliana as a case study | Journal of separation science | | 2007 | 599 | 2 | ||
| Multivariate data analysis of rapid LC-TOF/MS experiments from Arabidopsis thaliana stressed by wounding | Chemometrics and intelligent laboratory systems | | 2007 | 682 | 1 | ||
| Novel screening assay for antioxidant protection against peroxyl radical-induced loss of protein function | Journal of pharmaceutical sciences | | 2007 | 638 | 0 | ||
| Rapid determination of pK (a) values of 20 amino acids by CZE with UV and capacitively coupled contactless conductivity detections | Analytical & bioanalytical chemistry | | 2007 | 579 | 434 | ||
| NO-donor melatonin derivatives: synthesis and in vitro pharmacological characterization | Journal of pineal research | | 2007 | 599 | 0 | ||
| NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties | Journal of medicinal chemistry | | 2007 | 459 | 1 | ||
| Stereoselective block of hERG channel by (S)-methadone and QT interval prolongation in CYP2B6 slow metabolizers | Clinical pharmacology and therapeutics | | 2007 | 606 | 2 | ||
| Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinone cycle | Biochemical and biophysical research communications | | 2007 | 627 | 1 | ||
| Quantitative structure-permeation relationship for iontophoretic transport across the skin | Journal of controlled release | | 2007 | 592 | 0 | ||
| Immobilized pH gradient gel cell to study the pH dependence of drug lipophilicity | Analytical chemistry | | 2006 | 640 | 1 | ||
| Development of an in vitro rat intestine segmental perfusion model to investigate permeability and predict oral fraction absorbed | Pharmaceutical research | | 2006 | 614 | 264 | ||
| Impact of species-dependent differences on screening, design, and development of MAO B inhibitors | Journal of medicinal chemistry | | 2006 | 628 | 0 | ||
| Parallel artificial membrane permeability assay: a new membrane for the fast prediction of passive human skin permeability | Journal of medicinal chemistry | | 2006 | 601 | 0 | ||
| The lipophilicity behavior of three catechol-O-methyltransferase (COMT) inhibitors and simple analogues | Helvetica chimica acta | | 2006 | 579 | 0 | ||
| Structure-permeation relationships for the non-invasive transdermal delivery of cationic peptides by iontophoresis | European journal of pharmaceutical sciences | | 2006 | 666 | 0 | ||
| A study of interlaboratory influence on column evaluation | Journal of pharmaceutical and biomedical analysis | | 2005 | 546 | 0 | ||
| Experimental and virtual physicochemical and pharmacokinetic profiling of new chemical entities | Chimia | 2005 | 626 | 0 | |||
| Human recombinant monoamine oxidase B as reliable and efficient enzyme source for inhibitor screening | Bioorganic & medicinal chemistry | | 2005 | 609 | 0 | ||
| Synergy at the 'Ecole de Pharmacie Geneve-Lausannel': Methodology developments for the treatment of complex metabolomic datasets with data mining | Chimia | | 2005 | 603 | 324 | ||
| Numerical simulation of two-phase partition chromatography in microchannels for moderated log P measurements | Journal of chromatography | | 2005 | 595 | 0 | ||
| The medicinal chemist's dream: Faster design of better and safer drug candidates | Chimia | 2005 | 587 | 0 | |||
| Influence of lipophilicity and stereochemistry at the C-7 position on the cardioprotective and antioxidant effect of ginkgolides during rat heart ischemia and reperfusion | Drug development research | | 2005 | 544 | 3 | ||
| Novel RPLC stationary phases for lipophilicity measurement: solvatochromic analysis of retention mechanisms for neutral and basic compounds | Journal of separation science | | 2005 | 647 | 0 | ||
| Identification of novel multifunctional compounds for the treatment of some aging related neurodegenerative diseases | Chimia | 2005 | 549 | 0 | |||
| Ecole de Pharmacie Geneve-Lausanne: A novel center of excellence in Geneva | Chimia | 2005 | 386 | 0 | |||
| Fast determination of lipophilicity by HPLC | Chromatographia | | 2005 | 640 | 1 | ||
| Determination of pKa values by capillary zone electrophoresis with a dynamic coating procedure | Journal of separation science | | 2005 | 582 | 0 | ||
| A comparison of the solvation properties of 2-nitrophenyloctyl ether, nitrobenzene, and n-octanol as assessed by ion transfer experiments | The journal of physical chemistry. B | 2004 | 660 | 0 | |||
| Imidazole H3-antagonists: relationship between structure and ex vivo binding to rat brain H3-receptors | European journal of pharmaceutical sciences | | 2004 | 663 | 0 | ||
| Liposome/water lipophilicity: methods, information content, and pharmaceutical applications | Medicinal research reviews | | 2004 | 557 | 2 | ||
| Screening of non-alkaloidal natural compounds as acetylcholinesterase inhibitors | Chemistry & biodiversity | | 2004 | 590 | 0 | ||
| D-LogP: an alignment-free 3D description of local lipophilicity for QSAR studies | Methods in molecular biology | 2004 | 531 | 0 | |||
| Quantitative structure-permeation relationships (QSPeRs) to predict skin permeation: a critical evaluation | Pharmaceutical research | | 2004 | 579 | 0 | ||
| Fluoride curcumin derivatives: new mitochondrial uncoupling agents | FEBS letters | | 2004 | 724 | 1 | ||
| Analysis of basic compounds at high pH values by reversed-phase liquid chromatography | Journal of separation science | | 2004 | 636 | 0 | ||
| A graphical similarity function to help ligand docking to proteins based on the molecular lipophilicity potential : the case of the D2 dopamine receptor | Internet electronic journal of molecular design | | 2004 | 304 | 82 | ||
| Stabilization of the hydrophilic sphere of iobitridol | British journal of radiology | | 2003 | 537 | 0 | ||
| Solvatochromic analysis of partition coefficients in the o-nitrophenyl octyl ether (o-NPOE)/water system | Helvetica chimica acta | | 2003 | 600 | 0 | ||
| Immobilized artificial membrane HPLC in drug research | Journal of medicinal chemistry | | 2003 | 567 | 1 | ||
| Drug racemization and its significance in pharmaceutical research | Enantiomer | 2003 | 596 | 0 | |||
| Partition coefficients of ionizable compounds in o-nitrophenyl octyl ether/water measured by the potentiometric method | Analytical chemistry | | 2003 | 555 | 0 | ||
| An effective tool for column evaluation in the analysis of basic compounds | Chimia | | 2003 | 613 | 0 | ||
| Standard partition coefficients of anionic drugs in the n-octanol/water system determined by voltammetry at three-phase electrodes | PCCP. Physical chemistry chemical physics | | 2003 | 552 | 0 | ||
| Water-oil partition profiling of ionized drug molecules using cyclic voltammetry and a 96-well microfilter plate system | Pharmaceutical research | | 2003 | 489 | 1 | ||
| Synthesis and three-dimensional quantitative structure-activity relationship analysis of H3 receptor antagonists containing a neutral heterocyclic polar group | Drug design and discovery | | 2003 | 765 | 0 | ||
| Natural and synthetic geiparvarins are strong and selective MAO-B inhibitors. Synthesis and SAR studies | Bioorganic & medicinal chemistry letters | | 2002 | 675 | 0 | ||
| The Hydrogen-Bond: computational approaches and applications to drug design | Annales pharmaceutiques françaises | 2002 | 532 | 0 | |||
| Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB1 cannabinoid receptor ligands and potential antagonists: Synthesis, lipophilicity, affinity, and molecular modeling : additions and corrections | Journal of medicinal chemistry | | 2002 | 560 | 0 | ||
| Theoretical and experimental exploration of the lipophilicity of zwitterionic drugs in the 1,2-dichloroethane/water system | Pharmaceutical research | | 2002 | 530 | 0 | ||
| Protein protection by antioxidants: Development of a convenient assay and structure-activity relationships of natural polyphenols | Helvetica chimica acta | | 2002 | 518 | 0 | ||
| Exploration of the pharmacophore of 3-alkyl-5-arylimidazolidinediones as new CB(1) cannabinoid receptor ligands and potential antagonists: synthesis, lipophilicity, affinity, and molecular modeling | Journal of medicinal chemistry | | 2002 | 586 | 0 | ||
| Cyclic voltammetry of highly hydrophilic ions at a supported liquid membrane | Journal of electroanalytical chemistry and interfacial electrochemistry | | 2002 | 671 | 0 | ||
| Immobilized artificial membrane liquid chromatography: proposed guidelines for technical optimization of retention measurements | Journal of chromatography | | 2002 | 581 | 0 | ||
| Recognition forces involved in mitochondrial binding to a low-affinity trimetazidine binding site related to anti-ischemic activity | Biochemical pharmacology | | 2002 | 643 | 0 | ||
| Characterization of chromatographic supports for the analysis of basic compounds | Journal of separation science | | 2002 | 631 | 1 | ||
| Structural properties governing retention mechanisms on immobilized artificial membrane (IAM) HPLC columns | Helvetica chimica acta | | 2002 | 596 | 0 | ||
| Molecular factors influencing retention on immobilized artifical membranes (IAM) compared to partitioning in liposomes and n-octanol | Pharmaceutical research | | 2002 | 463 | 0 | ||
| A simple model to predict blood-brain barrier permeation from 3D molecular fields | Biochimica et biophysica acta | | 2002 | 620 | 0 | ||
| Lipophilicity and solvation of anionic drugs | Chemistry | | 2002 | 625 | 0 | ||
| The relative partitioning of neutral and ionised compounds in sodium dodecyl sulfate micelles measured by micellar electrokinetic capillary chromatography | European journal of pharmaceutical sciences | | 2002 | 635 | 0 | ||
| Quantitative structure-permeation relationships for solute transport across silicone membranes | Pharmaceutical research | | 2002 | 495 | 0 | ||
| Molecular hydrogen-bonding potentials (MHBPs) in structure-permeation relations | Pharmacokinetic optimization in drug research: Biological, physicochemical and computational strategies | 2001 | 599 | 0 | |||
| Structural damage to proteins caused by free radicals: asessment, protection by antioxidants, and influence of protein binding | Biochemical pharmacology | | 2001 | 460 | 0 | ||
| Molecular-dynamics and NMR investigation of the property space of the zwitterionic antihistamine cetirizine | Helvetica chimica acta | | 2001 | 653 | 1 | ||
| Interaction of psychotropic drugs with monoamine oxidase in rat brain | Journal of pharmacy and pharmacology | | 2001 | 543 | 0 | ||
| Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase | Journal of medicinal chemistry | | 2001 | 648 | 0 | ||
| Natural and synthetic xanthones as monoamine oxidase inhibitors: Biological assay and 3D-QSAR | Helvetica chimica acta | | 2001 | 629 | 0 | ||
| Generalization of ionic partition diagrams to lipophilic compounds and to biphasic systems with variable phase volume ratios | Journal of the American Chemical Society | | 2001 | 568 | 0 | ||
| Lipophilicity behaviour of the Zwitterionic antihistamine cetirizine in phosphatidylcholine liposomes/water systems | Pharmaceutical research | | 2001 | 643 | 0 | ||
| The apparent lipophilicity of quaternary ammonium ions is influenced by galvani potential difference, not ion-pairing: a cyclic voltammetry study | Pharmaceutical research | | 2001 | 588 | 0 | ||
| Novel basic isoflavones as inhibitors of bone resorption | Helvetica chimica acta | | 2001 | 563 | 0 | ||
| VolSurf and its application in structure-disposition relationships | Planta medica | 2001 | 476 | 0 | |||
| Ionic partition diagram of the zwitterionic antihistamine cetirizine | Helvetica chimica acta | | 2001 | 674 | 0 | ||
| The esterase-like activity of serum albumin may be due to cholinesterase contamination | Pharmaceutical research | | 2001 | 613 | 0 | ||
| Development of molecular hydrogen-bonding potentials (MHBPs) and their application to structure-permeation relations | Journal of molecular graphics & modelling | | 2001 | 565 | 0 | ||
| Physicochemical characterization of sildenafil: Ionization, lipophilicity behavior, and ionic-partition diagram sturdied by two-phase titration and electrochemistry | Helvetica chimica acta | | 2000 | 697 | 0 | ||
| Molecular fields in quantitative structure-permeation relationships: the VolSurf approach | Journal of molecular structure. Theochem | | 2000 | 791 | 0 | ||
| Predicting blood-brain barrier permeation from three-dimensional molecular structure | Journal of medicinal chemistry | | 2000 | 620 | 0 | ||
| Lipophilicity and related molecular properties as determinants of pharmacokinetic behaviour | Chimia | 2000 | 558 | 0 | |||
| The influence of lipophilicity on the pharmacokinetic behavior of drugs: Concepts and examples | Perspectives in drug discovery and design | | 2000 | 558 | 0 | ||
| Reversible inhibition of MAO-A and B by diazoheterocyclic compounds: Development of QSAR/CoMFA models | Helvetica chimica acta | 2000 | 561 | 0 | |||
| [Chirality and drugs] | Annales pharmaceutiques françaises | 2000 | 461 | 0 | |||
| Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs | Journal of medicinal chemistry | | 2000 | 628 | 0 | ||
| Very slow chiral inversion of clopidogrel in rats: a pharmacokinetic and mechanistic investigation | Drug metabolism and disposition | | 2000 | 678 | 0 | ||
| Monoamine oxidase inhibitor properties of some benzazoles: structure-activity relationships | AAPS PharmSci | 1999 | 531 | 0 | |||
| Ionic partition diagrams of ionisable drugs: pH-lipophilicity profiles, transfer mechanisms and charge effects on solvation | Journal of electroanalytical chemistry and interfacial electrochemistry | | 1999 | 675 | 0 | ||
| Production and characterization of 22 monoclonal antibodies directed against S 20499, a new potent 5-HT1A chiral agonist: influence of the hapten structure on specificity and stereorecognition | Pharmaceutical research | | 1999 | 629 | 0 | ||
| Effects of charge and intramolecular structure on the lipophilicity of nitrophenols | Journal of the American Chemical Society | | 1999 | 508 | 0 | ||
| Charge and delocalisation effects on the lipophilicity of protonable drugs | Chemistry | | 1999 | 608 | 0 | ||
| Structure-property relationships in the basicity and lipophilicity of arylalkylamine oxides | Helvetica chimica acta | | 1999 | 533 | 0 | ||
| The pH-partition profile of the anti-ischemic drug trimetazidine may explain its reduction of intracellular acidosis | Pharmaceutical research | | 1999 | 540 | 0 | ||
| Evaluation and prediction of drug permeation | Journal of pharmacy and pharmacology | | 1999 | 653 | 0 | ||
| Development of a capillary electrophoresis method to monitor protein oxidation and antioxidant protection | Helvetica chimica acta | | 1999 | 601 | 0 | ||
| Structure-lipophilicity relationships of neutral and protonated beta-blockers Part I Intra- and intermolecular effects in isotropic solvent systems | Helvetica chimica acta | | 1999 | 530 | 0 | ||
| Combined molecular lipophilicity descriptors and their role in understanding intramolecular effects | Pharmaceutical science & technology today | | 1999 | 586 | 0 | ||
| Origin of the stereoselectivity in (ethoxycarbonyl)-, cyano-, and phenyl-substituted (arylsulfinyl)methyl radicals | Helvetica chimica acta | 1998 | 599 | 0 | |||
| Mechanisms of liposomes/water partitioning of (p-methylbenzyl)alkylamines | Pharmaceutical research | | 1998 | 539 | 0 | ||
| Theoretical parameters to characterize antioxidants - Part 2 - The cases of melatonin and carvedilol | Helvetica chimica acta | 1998 | 579 | 0 | |||
| Evidence for the existence of [3H]-trimetazidine binding sites involved in the regulation of the mitochondrial permeability transition pore | British journal of pharmacology | | 1998 | 572 | 0 | ||
| Ligand specificity of the genetic variants of human alpha1-acid glycoprotein: generation of a three-dimensional quantitative structure-activity relationship model for drug binding to the A variant | Molecular pharmacology | | 1998 | 550 | 0 | ||
| Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist | Journal of medicinal chemistry | | 1998 | 739 | 0 | ||
| Chiral inversion and hydrolysis of thalidomide: mechanisms and catalysis by bases and serum albumin, and chiral stability of teratogenic metabolites | Helvetica chimica acta | | 1998 | 683 | 0 | ||
| Isoquinoline derivatives as endogenous neurotoxins in the aetiology of Parkinson's disease | Biochemical pharmacology | | 1998 | 677 | 0 | ||
| Structure-property relationships of trimetazidine derivatives and model compounds as potential antioxidants | Free radical biology & medicine | | 1998 | 656 | 0 | ||
| Intrinsic and intramolecular lipophilicity effects in O-glucuronides | Helvetica chimica acta | | 1998 | 553 | 1 | ||
| Synthesis, biological activity and molecular modelling of the 53-54 ketomethylene analogue of HEL(52-61) | Protein and peptide letters | 1998 | 549 | 0 | |||
| Mechanism and dynamics of methyl and ethyl orange transfer across the water/1,2-dichloroethane interface | Electrochimica acta | | 1998 | 658 | 0 | ||
| Facilitated ion transfer reactions across oil/water interfaces - Part II. Use of the convoluted current for the calculation of the association constants and for an amperometric determination of the stoichiometry of MLjz+ complexes | Journal of electroanalytical chemistry and interfacial electrochemistry | | 1998 | 385 | 0 | ||
| Inhibition of monoamine oxidase-B by condensed pyridazines and pyrimidines: Effects of lipophilicity and structure-activity relationships | Journal of medicinal chemistry | | 1998 | 556 | 0 | ||
| Molecular modeling of hen egg lysozyme HEL[52-61] peptide binding to I-A(k) MHC class II molecule | International immunology | | 1998 | 560 | 0 | ||
| Facilitated ion transfer reactions across oil vertical bar water interfaces. Part I. Algebraic development and calculation of cyclic voltammetry experiments for successive complex formation | Journal of electroanalytical chemistry and interfacial electrochemistry | | 1998 | 570 | 0 | ||
| Cyclic voltammetry for the transfer of multiple charged ions at large ITIES: General computational methodology and application to simple and facilitated ion transfer reactions | Journal of electroanalytical chemistry and interfacial electrochemistry | | 1997 | 573 | 0 | ||
| Esterase-like activity of human serum albumin toward prodrug esters of nicotinic acid | Drug metabolism and disposition | | 1997 | 594 | 0 | ||
| The origin of the difference between the C-13 and O-17 shift behaviour of carbonyl compounds RCOX: Ab initio calculation of the shielding tensors | Magnetic resonance in chemistry | | 1997 | 492 | 0 | ||
| Lipophilicity behavior of model and medicinal compounds containing a sulfide, sulfoxide, or sulfone moiety | Helvetica chimica acta | | 1997 | 539 | 0 | ||
| A systems approach to molecular structure, intermolecular recognition, and emergence-dissolvence in medicinal research | Medicinal research reviews | | 1997 | 592 | 0 | ||
| Intermolecular forces expressed in 1,2-dichloroethane-water partition coefficients - A solvatochromic analysis | Journal of the Chemical Society. Faraday transactions | 1997 | 553 | 0 | |||
| The racemization of enantiopure drugs: Helping medicinal chemists to approach the problem | Enantiomer | 1997 | 1,139 | 0 | |||
| Pharmacokinetics of beta-adrenoceptor blockers in obese and normal volunteers | British journal of clinical pharmacology | | 1997 | 642 | 0 | ||
| Theoretical parameters to characterize antioxidants.1. The case of vitamin E and analogs | Helvetica chimica acta | | 1997 | 570 | 1 | ||
| H3-receptor antagonists: synthesis and structure-activity relationships of para- and meta-substituted 4(5)-phenyl-2-[[2-[4(5)-imidazolyl]ethyl]thio]imidazoles | Helvetica chimica acta | | 1997 | 579 | 0 | ||
| Blood-to-brain transfer of various oxicams: effects of plasma binding on their brain delivery | Pharmaceutical research | | 1997 | 581 | 0 | ||
| The molecular behaviour of cetirizine | Clinical and experimental allergy | 1997 | 444 | 0 | |||
| A cellular automata model of diffusion in aqueous systems | Journal of pharmaceutical sciences | | 1997 | 572 | 0 | ||
| Lipophilicity Profiles of Ampholytes | Chemical reviews | | 1997 | 573 | 0 | ||
| Solvatochromic analysis of di-n-butyl ether/water partition coefficients as compared to other solvent systems | Journal of the Chemical Society. Perkin transactions II | 1997 | 597 | 0 | |||
| Kinetics and mechanisms of racemization: 5-substituted hydantoins (=imidazolidine-2,4-diones) as models of chiral drugs | Helvetica chimica acta | | 1996 | 576 | 0 | ||
| Ionization and partitioning profiles of zwitterions: The case of the anti-inflammatory drug azapropazone | Helvetica chimica acta | | 1996 | 579 | 0 | ||
| A cellular automata model of micelle formation | Pharmaceutical research | | 1996 | 498 | 0 | ||
| A cellular automata model of enzyme kinetics | Pharmaceutical research | | 1996 | 589 | 0 | ||
| Knowledge-based modeling of a legume lectin and docking of the carbohydrate ligand: the Ulex europaeus lectin I and its interaction with fucose | Journal of molecular graphics | | 1996 | 1,043 | 1 | ||
| Trimetazidine reverses calcium accumulation and impairment of phosphorylation induced by cyclosporine A in isolated rat liver mitochondria | The Journal of pharmacology and experimental therapeutics | | 1996 | 481 | 0 | ||
| Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models | Journal of medicinal chemistry | | 1996 | 569 | 0 | ||
| Diastereoselective radical alkylations of alkyl aryl sulfoxides | Tetrahedron letters | | 1996 | 594 | 0 | ||
| Toxicity to PC12 cells of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Neuroscience letters | | 1996 | 622 | 0 | ||
| Insight into the lipophilicity of the aromatic N-oxide moiety | Pharmaceutical research | 1996 | 597 | 0 | |||
| How do antibodies and lectins recognize histo-blood group antigens? A 3D-QSAR study by comparative molecular field analysis (CoMFA) | Bioorganic & medicinal chemistry | | 1996 | 661 | 0 | ||
| Transfer mechanism of ionic drugs: Piroxicam as an agent facilitating proton transfer | Helvetica chimica acta | | 1996 | 593 | 0 | ||
| Nigral cell loss produced by infusion of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Neurodegeneration | | 1996 | 612 | 0 | ||
| Lipophilicity in molecular modeling | Pharmaceutical research | 1996 | 514 | 0 | |||
| Electrochemical behaviour and antioxidant activity of some natural polyphenols | Helvetica chimica acta | | 1996 | 553 | 0 | ||
| NMR of terminal oxygen.17. Ab initio IGLO study of the high shielding of O (and C, N) in linear heteronuclear pi-systems | Magnetic resonance in chemistry | | 1996 | 505 | 0 | ||
| Ionic partition diagrams: A Potential pH representation | Journal of the American Chemical Society | | 1996 | 610 | 0 | ||
| Effects of isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on mitochondrial respiration | Biochemical pharmacology | | 1996 | 624 | 0 | ||
| A continuous fluorimetric method to monitor the enzymatic hydrolysis of medicinal esters | Journal of pharmaceutical and biomedical analysis | | 1996 | 540 | 0 | ||
| Molecular lipophilicity potential (MLP) in drug design. Complementing theoretical tools with experimental results | Journal de pharmacie de Belgique | 1996 | 604 | 0 | |||
| Mechanism of transfer of a basic drug across the water 1,2-dichloroethane interface: The case of quinidine | Helvetica chimica acta | | 1996 | 550 | 0 | ||
| Inhibition of [3H]dopamine uptake into striatal synaptosomes by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | Biochemical pharmacology | | 1996 | 619 | 0 | ||
| Measurement of Partition-Coefficient Using Centrifugal Partition Chromatography - Method Development and Application to the Determination of Solute Properties | Abstracts of papers - American Chemical Society | 1995 | 583 | 0 | |||
| Inhibition of monoamine oxidase by isoquinoline derivatives. Qualitative and 3D-quantitative structure-activity relationships | Biochemical pharmacology | | 1995 | 696 | 0 | ||
| Inhibition of complex I by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) | Biochemical pharmacology | | 1995 | 620 | 0 | ||
| Structure-Lipophilicity and Structure-Polarity Relationships of Amino-Acids and Peptides | Helvetica chimica acta | 1995 | 645 | 0 | |||
| Inhibition of alpha-ketoglutarate dehydrogenase by isoquinoline derivatives structurally related to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) | Neuroreport | 1995 | 554 | 0 | |||
| Low Configurational Stability of Amfepramone and Cathinone - Mechanism and Kinetics of Chiral Inversion | Chirality | 1995 | 668 | 0 | |||
| A cellular automata model of the hydrophobic effect | Pharmaceutical research | 1995 | 431 | 0 | |||
| Esters of L-dopa: structure-hydrolysis relationships and ability to induce circling behaviour in an experimental model of hemiparkinsonism | Journal of pharmacy and pharmacology | 1995 | 642 | 0 | |||
| Mechanism of ligand binding to alpha 1-acid glycoprotein (orosomucoid): correlated thermodynamic factors and molecular parameters of polarity | Biochemical journal | | 1995 | 553 | 0 | ||
| Stabilization of the hydrophilic sphere of iobitridol, an iodinated contrast agent, as revealed by experimental and computational investigations | Pharmaceutical research | 1995 | 552 | 0 | |||
| Inhibition of monoamine oxidase-B by 5H-indeno[1,2-c]pyridazines: biological activities, quantitative structure-activity relationships (QSARs) and 3D-QSARs | Journal of medicinal chemistry | | 1995 | 579 | 0 | ||
| Additions et corrections : structure genotoxicity relationships of allylbenzenes and propenylbenzenes - A quantum-chemical Study | Chemical research in toxicology | | 1995 | 534 | 0 | ||
| Structure-affinity relationships of baclofen and 3-heteroaromatic analogues | Bioorganic & medicinal chemistry | | 1995 | 611 | 0 | ||
| Nmr of terminal oxygen.15. O-17 Nmr-spectra of the N+-O- group - tert-amine oxides R(3)N(+)O(-), nitrones -Hc=N+(-O-)-, azoxy derivatives -N=N+(-O-)-, nitrile oxides -C-N+-O- and related-compounds - shielding anisotropy in linear heteroatomar Pi-systems | Magnetic resonance in chemistry | 1995 | 525 | 0 | |||
| Structural-Properties Governing Retention Mechanisms on Rp-Hplc Stationary Phases Used for Lipophilicity Measurements | Journal of liquid chromatography | 1995 | 619 | 0 | |||
| Racemization, Enantiomerization, Diastereomerization, and Epimerization - Their Meaning and Pharmacological Significance | Chirality | 1995 | 1,200 | 0 | |||
| X-ray crystal structure, partitioning behavior, and molecular modeling study of piracetam-type nootropics: insights into the pharmacophore | Journal of medicinal chemistry | | 1995 | 614 | 0 | ||
| Microscopic Protonation Deprotonation Equilibria of the Antiinflammatory Agent Piroxicam | Helvetica chimica acta | 1995 | 503 | 0 | |||
| Pi-facial diastereoselection in [4+2]-cycloadditions of 3,4-epoxy-2-methyleneoxolanes with oxadienes : a short synthesis of spiroketals | Tetrahedron | 1994 | 457 | 0 | |||
| Solute water interactions in the organic-phase of a biphasic system.2. effects of organic-phase and temperature on the water-dragging effect | Journal of physical chemistry | | 1994 | 560 | 0 | ||
| Stereochemical study of the allylation of 1-phenylsulfinylethyl and 1-phenylsulfinyl-2,2,2-trifluoroethyl radicals | Tetrahedron letters | 1994 | 548 | 0 | |||
| Lipophilicity and hydrogen-bonding capacity of H-1-antihistaminic agents in relation to their central sedative side-effects | European journal of pharmaceutical sciences | 1994 | 763 | 0 | |||
| Molecular modeling in drug design : funny, futile, Or fertile | Chimia | 1994 | 458 | 0 | |||
| Structure-genotoxicity relationships of allylbenzenes and propenylbenzenes: a quantum chemical study | Chemical research in toxicology | | 1994 | 611 | 1 | ||
| Molecular lipophilicity potential, a tool in 3D QSAR: method and applications | Journal of computer-aided molecular design | 1994 | 659 | 0 | |||
| The conformation-dependent lipophilicity of morphine glucuronides as calculated from their molecular lipophilicity potential | Bioorganic & medicinal chemistry letters | 1994 | 635 | 0 | |||
| Chirality in drug research - stereomania, stereophobia, or stereophilia | Chimia | 1993 | 473 | 0 | |||
| Physicochemical and structural-properties of nonsteroidal antiinflammatory oxicams | Helvetica chimica acta | 1993 | 617 | 0 | |||
| The optical resolution of bicyclo[2.2.1]Hept-5-Ene-2-cyanohydrins using brucine : a crystallographic and molecular-mechanics study | Acta crystallographica. Section C, Crystal structure communications | 1993 | 567 | 0 | |||
| Influence of stereochemical factors on the partition-coefficient of diastereoisomers in a biphasic octan-1-Ol water-system | Journal of chemical research. Synopses | 1993 | 519 | 0 | |||
| Lipophilicity and hydrogen-bonding capacity : their role in drug-binding and disposition | Chirality | 1993 | 462 | 0 | |||
| Solute water interactions in the organic-phase of a biphasic system.1. Structural influence of organic solutes on the water-dragging effect | Journal of the American Chemical Society | | 1993 | 546 | 0 | ||
| Enantiomeric resolution of sulfoxides on a Dach-Dnb chiral stationary-phase : a quantitative structure-enantioselective retention relationship (Qserr) study | Chirality | 1993 | 603 | 0 | |||
| Measurement of partition-coefficients using centrifugal partition chromatography : method development and application to the determination of solute structural-properties | Abstracts of papers - American Chemical Society | 1993 | 471 | 0 | |||
| Stereoselectivity of the radical reductive alkylation of enamines - importance of the allylic 1,3-strain model | Helvetica chimica acta | 1993 | 584 | 0 | |||
| Effects of Solvation on the Ionization and Conformation of Raclopride and Other Antidopaminergic 6-Methoxysalicylamides - Insight Into the Pharmacophore. [Erratum to document cited in CA118(7):51870w] | Journal of medicinal chemistry | | 1993 | 612 | 0 | ||
| Effects of solvation on the ionization and conformation of raclopride and other antidopaminergic 6-methoxysalicylamides: insight into the pharmacophore | Journal of medicinal chemistry | | 1993 | 568 | 0 | ||
| Clinical-pharmacology of oxicams - new insights into the mechanisms of their dose-dependent toxicity | International journal on tissue reactions | 1993 | 591 | 0 | |||
| The so-called "interconversion" of stereoisomeric drugs: an attempt at clarification | Chirality | 1993 | 593 | 0 | |||
| Solvatochromic analysis of the retention mechanism of 2 novel stationary phases used for measuring lipophilicity by Rp-Hplc | Journal of liquid chromatography | 1992 | 548 | 0 | |||
| Octan-1-Ol-water partition-coefficients of zwitterionic alpha-amino-acids - determination by centrifugal partition chromatography and factorization into steric hydrophobic and polar components | Journal of the Chemical Society. Perkin transactions II | 1992 | 599 | 0 | |||
| Conformational-analysis of alpha-methoxyketones : a photoelectron spectroscopic investigation of 3-Methoxybicyclo[2.2.1]Heptan-2-Ones | Tetrahedron | 1992 | 533 | 0 | |||
| Quantitative structure-metabolism relationship analyses of MAO-mediated toxication of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and analogues | Chemical research in toxicology | | 1992 | 555 | 0 | ||
| Physicochemical properties and transport behavior of piribedil : considerations on its membrane-crossing potential | International journal of pharmaceutics | 1992 | 533 | 0 | |||
| Polar intermolecular interactions encoded in partition-coefficients :an indirect estimation of hydrogen-bond parameters of polyfunctional solutes | Journal of physical chemistry | | 1992 | 572 | 0 | ||
| The hydrogen-bonding of drugs : Its experimental-determination and role in pharmacokinetics and pharmacodynamics | Chirality | 1992 | 554 | 0 | |||
| A model for the stereoselectivity of radical mediated reductive alkylation of acyclic enamines | Synlett | 1992 | 508 | 0 | |||
| Electronic and Conformational Effects on the Lipophilicity of Isomers and Analogs of the Neurotoxin 1-Methyl-4-Phenylpyridinium (Mpp+) | Helvetica chimica acta | 1991 | 606 | 0 | |||
| Structure lipophilicity relationships of zwitterionic amino-acids | Journal of the Chemical Society. Perkin transactions II | 1991 | 591 | 0 | |||
| Quantitative structure-affinity relationships of dopamine D2 receptor antagonists - a comparison between orthopramides and 6-methoxysalicylamides | Helvetica chimica acta | 1991 | 560 | 0 | |||
| Morphine 6-Glucuronide and Morphine 3-Glucuronide As Molecular Chameleons with Unexpected Lipophilicity | Journal of medicinal chemistry | | 1991 | 975 | 0 | ||
| Ionization behavior and ionization-dependent conformation of raclopride, a dopamine-D2 receptor antagonist | Helvetica chimica acta | 1991 | 558 | 0 | |||
| The structure of the molecular ion of allyl bromide | International journal of mass spectrometry and ion processes | 1991 | 566 | 0 | |||
| Molecular electrostatic potentials for characterizing drug-biosystem interactions | Methods in enzymology | 1991 | 558 | 0 | |||
| Percutaneous penetration of drugs: a quantitative structure-permeability relationship study | Journal of pharmaceutical sciences | 1991 | 516 | 0 | |||
| Partitioning of solutes in different solvent systems: the contribution of hydrogen-bonding capacity and polarity | Journal of pharmaceutical sciences | 1991 | 542 | 0 | |||
| Comparison of the Performances of the Gaussian and Cadpac-Abinitio Program Packages on Different Computers | Chimia | 1991 | 528 | 0 | |||
| Toxication of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) and analogs by monoamine oxidase. A structure-reactivity relationship study | Biochemical pharmacology | 1990 | 544 | 0 | |||
| Interaction Between Oxygen Lone-Pair Orbitals of Ether and Alpha,Beta-Unsaturated Ketone Functions in 3,5,6-Trimethylidene-7-Oxabicyclo[2.2.1]Heptan-2-One and 3,6-Dimethylidene-7-Oxabicyclo[2.2.1]Heptane-2,5-Dione - A Pe-Spectroscopic Investigation | Helvetica chimica acta | 1990 | 476 | 0 | |||
| Through-Bond Interactions of Beta-Carbonyl and Beta-Imine Lone Pairs with Cationic 2P Orbital - Quantum Calculations on Bicyclo[2.2.2]Oct-1-Yl Cation and Derivatives | Journal of organic chemistry | | 1990 | 495 | 0 | ||
| The MPTP story: MAO activates tetrahydropyridine derivatives to toxins causing parkinsonism | Drug metabolism reviews | | 1990 | 509 | 0 | ||
| Multivariate data analyses of QSAR parameters | Progress in clinical and biological research | 1989 | 499 | 0 | |||
| Lipophilicity and conformational behaviour of substituted xanthines | Progress in clinical and biological research | 1989 | 477 | 0 | |||
| Beta-adrenoceptor modeling based on MEP studies | Progress in clinical and biological research | 1989 | 490 | 0 | |||
| Pattern recognition study of QSAR substituent descriptors | Journal of computer-aided molecular design | 1989 | 567 | 0 | |||
| 8-Substituted Xanthines As Phosphodiesterase Inhibitors - Conformation-Dependent Lipophilicity and Structure-Activity-Relationships | Helvetica chimica acta | 1989 | 547 | 0 | |||
| Isotope effects on the lipophilicity of deuterated caffeines | Helvetica chimica acta | 1989 | 640 | 0 | |||
| Stereoelectronic study of zetidoline, a dopamine D2 receptor antagonist | Journal of medicinal chemistry | | 1989 | 671 | 0 | ||
| Hydration of substituted benzenes - experimental studies and relationship with lipophilicity | International journal of pharmaceutics | 1989 | 527 | 0 | |||
| The Electron-Donating Carbonyl Group Total Synthesis of Rare Sugars | Abstracts of papers - American Chemical Society | 1989 | 494 | 0 | |||
| DESBASE, a multiparameter substituent database | Progress in clinical and biological research | 1989 | 548 | 0 | |||
| Solvent-dependent lipophilicity and hydrogen-bonding capacity of 2-pyridylalkanols | International journal of pharmaceutics | 1989 | 521 | 0 | |||
| The Carbonyl Group As Homoconjugated Electron-Releasing Substituent - Regioselective Electrophilic Additions at Bicyclo[2.2.1]Hept-5-En-2-One, Bicyclo[2.2.2]Oct-5-En-2-One and Derivatives | Helvetica chimica acta | 1989 | 525 | 0 | |||
| The Influence of Hydration and Structure-Promoting Effects on the Viscosity of Binary Solvent Mixtures | International journal of pharmaceutics | 1988 | 529 | 0 | |||
| Abinitio Mo calculations on the rearrangements of 7-Oxa-2-Bicyclo[2.2.1]Heptyl cations - the facile migration of acyl group in Wagner-Meerwein rearrangements | Journal of physical organic chemistry | 1988 | 592 | 0 | |||
| Isotope Effects on Lipophilicity and Polarity | Applied radiation and isotopes | 1988 | 539 | 0 | |||
| Circular Dichroism of Planar, Exocyclic S-cis-Butadienes Remotely Perturbed | Helvetica chimica acta | 1988 | 586 | 0 | |||
| Influence of lipophilicity and chirality on the selectivity of ligands for beta 1- and beta 2-adrenoceptors | Journal of pharmacy and pharmacology | 1988 | 522 | 0 | |||
| Synthesis of optically pure tricarbonyliron complexes of 5,6-dimethylidenebicyclo[222]Oct-2-Yl derivatives - crystal-structure and absolute-configuration of (+)-tricarbonyl[(1S,2S,4R,5R,6S)-C,5,6,C-eta-(5,6-fimethylidenebicyclo[2 22]Oct-2-Yl P-bromobenzoate)]iron | Helvetica chimica acta | 1988 | 433 | 0 | |||
| Study of Intramolecular Hydrogen-Bonding in Ortho-Anisic Acid and Ortho-Anisamide by O-17 Nmr and Abinitio Mo Calculations | Magnetic resonance in chemistry | 1988 | 458 | 0 | |||
| Modeling of beta-adrenoceptors based on molecular electrostatic potential studies of agonists and antagonists | Journal of medicinal chemistry | | 1988 | 563 | 0 | ||
| Synthesis and Circular-Dichroism of 5-Halogenobicyclo[2.2.1]Hept-5-En-2-Ones and 6-Halogenobicyclo[2.2.1]Hept-5-En-2-Ones - Tests for the Dekkers Quantitative Chirality Rule | Chimia | 1988 | 477 | 0 | |||
| Intramolecular Diels-Alder Reactions of 3H-Pyrroles Resulting from the Thermal Rearrangements of 2H-Pyrroles | Journal of organic chemistry | | 1987 | 585 | 0 | ||
| Interactions between oxygen lone-pair orbitals and double-bond pi-orbitals in beta,gamma-unsaturated, bicyclic ketones - A pe-spectroscopic investigation | Helvetica chimica acta | 1987 | 506 | 0 | |||
| Interactions between nonconjugated chromophores.28. regioselective electrophilic additions of bicyclo[2.2.N]Alk-2-enes controlled by remote epoxide functions | Helvetica chimica acta | 1987 | 415 | 0 | |||
| Dynamic Modeling of Diels-Alder Reaction Using Computer-Graphics | Journal de chimie physique | 1987 | 494 | 0 | |||
| Dynamic modeling of chemical-reactions : the diels-alder cycloaddition | Journal of molecular graphics | 1987 | 532 | 0 | |||
| The influence of aromatic substituents on the binding of substituted benzamides to dopamine D-2 receptors: congruent QSAR and MEP analyses | Journal of pharmacy and pharmacology | 1987 | 500 | 0 | |||
| Similarities of Pharmacophoric Patterns Revealed by the Mep of Metoclopramide, Molindone and Piquindone, A Subgroup of Dopamine D-2 Receptor Antagonists | Journal of molecular graphics | 1986 | 592 | 0 | |||
| Pyrimidalization of the Carbon-Atom of the Nitrogen-Carbon Double-Bond of 2-Azabicyclo[2.2.1]Hept-2-Enes - Radiocrystallographic Study and Calculations of Quantum-Mechanics | Nouveau journal de chimie | 1986 | 377 | 0 | |||
| Experimental and Theoretical-Studies on the Homoconjugation in Bicyclic Carbenium and Oxonium Ions in the Gas-Phase | Tetrahedron letters | 1986 | 539 | 0 | |||
| Regioselectivity of 1,3-Dipolar Cycloadditions Controlled by Remote Substitution and Lewis Acid Catalysts | Heterocycles | 1986 | 540 | 0 | |||
| 3-Dimensional and Electronic Analysis of Na+-Dependent Antidopaminergic Agents - Tropapride and Zetidoline | Journal of molecular graphics | 1986 | 518 | 0 | |||
| Conformation, Electrostatic Potential and Pharmacophoric Pattern of Orthopramides and Other Dopamine Receptor Antagonists | Journal of molecular structure. Theochem | 1986 | 544 | 0 | |||
| Chemoselective and Stereoselective Functionalization of 7-Oxabicyclo[2.2.1]Hept-5-En-2-One with Dichloroketene | Tetrahedron letters | 1986 | 400 | 0 | |||
| Molecular electrostatic potential of orthopramides: implications for their interaction with the D-2 dopamine receptor | Journal of medicinal chemistry | | 1986 | 639 | 0 | ||
| The electronic-structure of dopamine - an abinitio electrostatic potential study of the catechol moiety | Helvetica chimica acta | 1985 | 466 | 0 | |||
| Face Selectivity in the Diels-Alder Additions and Chelotropic Addition of Sulfur-Dioxide to 2-(D)Methylidene-3-Methylidenebicyclo[2.2.1]Heptane | Helvetica chimica acta | 1985 | 489 | 0 | |||
| Experimental and Abinitio Molecular-Orbital Studies on Collisions of Ch4+. and Ch5+ with Molecular-Oxygen - on the Formation of Methane (Ch4(2+)) and Methonium (Ch5(2+)) Dications and Stable Chn-Species (N = 0-3) | Journal of the American Chemical Society | | 1985 | 532 | 0 | ||
| Double-bond pyramidalization in bicyclic alkanes - abinitio mo calculations on bicyclo[2.2.1]hept-2-ene, bicyclo[2.1.1]hex-2-ene and bicyclo[3.2.1]Oct-6-Ene derivatives | Journal of molecular structure. Theochem | 1985 | 541 | 0 | |||
| H-1-Nmr spectra of cyclohexa-1,4-dienes and cyclohexenes annellated to bicyclo[2.2.1]Hept-2-Enes - the inter-ring homoallylic H,H coupling-constants as stereochemical probes | Helvetica chimica acta | 1985 | 559 | 0 | |||
| The Non-Planarity of the Bicyclo[2.2.1]Hept-2-Ene Double-Bond - Crystal-Structures of Bicyclo[2.2.2]Oct-2-Ene, Bicyclo[2.2.1]Hept-2-Ene, and Bicyclo[2.1.1]Hex-2-Ene Systems | Helvetica chimica acta | 1984 | 531 | 0 | |||
| Molecular-Ions of Transient Species - Vinylamine-Cation | Helvetica chimica acta | 1984 | 609 | 0 | |||
| The Carbonyl Group As Homoconjugated Electron Donating Substituent - Abinitio Sto 3G Mo Calculations | Tetrahedron letters | 1984 | 561 | 0 | |||
| The Circular-Dichroism of 5,6-Dimethylidene-2-Bicyclo[2.2.N]Alkyl Esters - Chiral Exciton Coupling Between Benzoate and Exocyclic S-Cis-Butadiene Chromophores | Helvetica chimica acta | 1984 | 484 | 0 | |||
| Stereoselective Control in the Base-Catalyzed H/D Exchange of 5,6-Dimethylidene-2-Bicyclo[2.2.N]Alkanone Tricarbonyliron Complexes - Revision of the Structures of Tricarbonyliron Complexes of 5,6-Dimethylidenebicyclo[2.2.2]Oct-2-Ene and 5,6-Dimethylidenebicyclo[2.2.1]Hept-2-Ene | Chimia | 1984 | 528 | 0 | |||
| Site of Protonation and Conformational Effects on Gas-Phase Basicity in Beta-Amino Alcohols - the Nature of Internal H-Bonding in Beta-Hydroxy Ammonium-Ions | Journal of the American Chemical Society | | 1983 | 525 | 0 | ||
| Dynamic representation of quantum chemical results using computer-graphics - molecular-rearrangements, art or science | Journal of molecular structure. Theochem | 1983 | 559 | 0 | |||
| Interactions between homoconjugated diene and epoxide functions - effect on diels-alder regioselectivity | Tetrahedron letters | 1983 | 562 | 0 | |||
| The Circular-Dichroism of 2,3-Dimethylidene-5-Norbornyl Derivatives | Tetrahedron letters | 1983 | 996 | 0 | |||
| Interactions Between Non-Conjugated Chromophores.13. Interaction Between Exocyclic S-Cis-Butadiene and Homoconjugated Functions - Preparation and Diels-Alder Reactivity of Remotely Substituted 2,3-Dimethylidenebicyclo[2.2.2]Octanes | Helvetica chimica acta | 1982 | 457 | 0 | |||
| Regioselective additions of electrophiles to olefins remotely perturbed - the carbonyl group as a homoconjugated electron donating substituent | Tetrahedron letters | 1982 | 560 | 0 | |||
| Synthesis and diels-alder reactivity of 7-isopropylidene-2,3,5,6-tetramethylenebicyclo-[2.2.1]heptane (7,7-Dimethyl[2.2.1]Hericene) | Journal of organic chemistry | | 1982 | 543 | 0 | ||
| Interaction Between Non-Conjugated Chromophores.14. Regioselectivity of the Diels-Alder Additions of 2-Substituted 5,6-Dimethylidenenorbornanes and Dimethylidenebicyclo[2.2.2]Octanes | Helvetica chimica acta | 1982 | 435 | 0 | |||
| A theoretical conformational study of substituted O-anisamides as models of a class of dopamine antagonists | Journal of pharmacy and pharmacology | 1981 | 497 | 0 | |||
| Charge-transfer bands of bicyclic beta, gamma-unsaturated ketones - circular-dichroism of (+)-(1R)-5,6-dimethylidene-2-bicyclo[2.2.2]octanone and (+)-(1R)-2-bicyclo[2.2.2]Oct-5-enone | Tetrahedron letters | 1981 | 488 | 0 | |||
| Non-planarity of pi-systems in 5,6-bis(methylene)-7-oxanorborn-2-ene | Journal of the American Chemical Society | | 1981 | 479 | 0 | ||
| O-17 Nuclear Magnetic-Resonance - the Effects of Remote Unsaturation on O-17-Chemical Shifts in Polycyclic Ethers | Tetrahedron | 1980 | 417 | 0 | |||
| An efficient synthesis of 2,3,5,6-tetramethylidene-7-oxanorbornane | Helvetica chimica acta | 1980 | 541 | 0 | |||
| New, doubly convergent synthesis of anthracyclinones - diels-alder additions to 2,3,5,6-tetrakis(methylene)-7-oxanorbornane | Tetrahedron letters | 1979 | 616 | 0 | |||
| Radical Cation States of 2,3,5,6-Tetramethylenenorbornane, 2,3,5,6-Tetramethylenebicyclo[2.2.2]Octane and of Related Compounds | Recueil des travaux chimiques des Pays-Bas | 1979 | 539 | 0 | |||
| Iron and Molybdenum Carbonyls of 5,6-Dimethylene-7-Oxabicyclo[2.2.1]Hept-2-Ene - Crystal and Molecular-Structure of (C8H8O)Fe2(Co)7 | Inorganica Chimica Acta | 1978 | 567 | 0 | |||
| Regioselectivity of diels-alder cycloadditions of 2-substituted 5,6-bis(methylene)-norbornanes | Tetrahedron letters | 1978 | 544 | 0 | |||
| Hyperconjugative interactions in bicyclo[2.2.1)heptane derivatives - effects on diels-alder reactivity of S-Cis-butadiene group of 2,3-dimethylidene-norbornanes | Helvetica chimica acta | 1976 | 464 | 0 |
