Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

Rutti Roch, Sabine; Arous, Caroline; Schvartz, Domitille; Timper, Katharina; Sanchez, Jean-Charles; Dermitzakis, Emmanouil; Donath, Marc Y; Halban, Philippe A.; Bouzakri, Karim

doi:10.1016/j.molmet.2014.07.007

Scientific article

English

Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

ContributorsRutti Roch, Sabine; Arous, Caroline; Schvartz, Domitille; Timper, Katharina; Sanchez, Jean-Charles

; Dermitzakis, Emmanouil; Donath, Marc Y; Halban, Philippe A.; Bouzakri, Karim

Published inMolecular metabolism, vol. 3, no. 7, p. 731-741

Publication date2014

Abstract

We have previously shown the existence of a muscle-pancreas intercommunication axis in which CX3CL1 (fractalkine), a CX3C chemokine produced by skeletal muscle cells, could be implicated. It has recently been shown that the fractalkine system modulates murine β-cell function. However, the impact of CX3CL1 on human islet cells especially regarding a protective role against cytokine-induced apoptosis remains to be investigated.

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Citation (ISO format)

RUTTI ROCH, Sabine et al. Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα. In: Molecular metabolism, 2014, vol. 3, n° 7, p. 731–741. doi: 10.1016/j.molmet.2014.07.007

Article (Accepted version)

Identifiers

PID : unige:41518
DOI : 10.1016/j.molmet.2014.07.007
PMID : 25353001

Journal ISSN2212-8778

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Creation03/11/2014 10:53:00

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Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα

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