| IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death | Molecular metabolism | | | 2016 | 566 | 216 |
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| Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression | The Journal of biological chemistry | | | 2015 | 586 | 2 |
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| Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα | Molecular metabolism | | | 2014 | 700 | 481 |
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| β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment | Diabetes care | | | 2014 | 856 | 1,088 |
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| Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells | FEBS letters | | | 2014 | 785 | 460 |
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| β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment | The Journal of clinical endocrinology and metabolism | | | 2014 | 697 | 1,115 |
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| Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats | PloS one | | | 2014 | 677 | 307 |
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| Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model | Diabetologia | | | 2013 | 618 | 436 |
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| Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion | Diabetologia | | | 2013 | 599 | 1,554 |
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| Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome | Genome research | | | 2013 | 721 | 617 |
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| Autonomous and self-sustained circadian oscillators displayed in human islet cells | Diabetologia | | | 2013 | 767 | 241 |
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| A new paradigm for improved co-ordination and efficacy of European biomedical research: taking diabetes as a model | Diabetologia | | | 2013 | 645 | 402 |
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| In vitro proliferation of adult human beta-cells | PloS one | | | 2012 | 725 | 480 |
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| Bimodal impact of skeletal muscle on pancreatic β-cell function in health and disease | Diabetes, obesity & metabolism | | | 2012 | 710 | 960 |
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| Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion | The Journal of biological chemistry | | | 2012 | 707 | 643 |
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| Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin | Diabetes | | | 2011 | 638 | 483 |
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| Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto-Kakizaki (GK) rat | Diabetologia | | | 2011 | 694 | 449 |
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| Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle | Diabetes | | | 2011 | 653 | 2 |
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| Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells | Nature medicine | | | 2011 | 899 | 1,389 |
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| Prime time for DIAMAP: a road map for diabetes research in Europe | Diabetologia | | | 2010 | 537 | 188 |
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| Cytokine production by islets in health and diabetes: cellular origin, regulation and function | Trends in endocrinology and metabolism | | | 2010 | 584 | 1 |
|
| Current status of islet cell replacement and regeneration therapy | The Journal of clinical endocrinology and metabolism | | | 2010 | 619 | 0 |
|
| Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate | Traffic | | | 2010 | 584 | 0 |
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| Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion | The Journal of biological chemistry | | | 2009 | 646 | 0 |
|
| Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix | Molecular endocrinology | | | 2009 | 586 | 0 |
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| Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function | Endocrinology | | | 2009 | 691 | 0 |
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| Order! Order! Order in the House! DIAMAP: a road map for European diabetes research | Diabetologia | | | 2008 | 541 | 157 |
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| Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture | Diabetes | | | 2008 | 648 | 0 |
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| Interleukin-6 regulates pancreatic alpha-cell mass expansion | Proceedings of the National Academy of Sciences of the United States of America | | | 2008 | 609 | 0 |
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| Proliferation of sorted human and rat beta cells | Diabetologia | | | 2008 | 931 | 322 |
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| The right stuff: beta-cell channels, cycles, and sensors | American journal of physiology: endocrinology and metabolism | | | 2008 | 550 | 0 |
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| Munc 18-1 and granuphilin collaborate during insulin granule exocytosis | Traffic | | | 2008 | 716 | 0 |
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| Cell therapy for type 2 diabetes: is it desirable and can we get it? | Diabetes, obesity & metabolism | | | 2008 | 637 | 0 |
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| Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells | Diabetes | | | 2008 | 631 | 0 |
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| Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation | The Journal of clinical endocrinology and metabolism | | | 2008 | 659 | 252 |
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| Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14 | Diabetes | | | 2008 | 587 | 1,403 |
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| Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion | Endocrinology | | | 2008 | 665 | 0 |
|
| Dynamin is functionally coupled to insulin granule exocytosis | The Journal of biological chemistry | | | 2007 | 649 | 0 |
|
| Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells | Endocrinology | | | 2007 | 579 | 0 |
|
| The innovative medicines initiative (IMI): a shot in the arm for European diabetes research? | Diabetologia | | | 2007 | 609 | 196 |
|
| The Fas pathway is involved in pancreatic beta cell secretory function | Proceedings of the National Academy of Sciences of the United States of America | | | 2007 | 692 | 0 |
|
| Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity | Journal of Endocrinology | | | 2007 | 606 | 0 |
|
| Comment faire renaître la cellule beta du sacrifice en sauveur | Journées annuelles de diabétologie de l'Hôtel-Dieu | | | 2007 | 491 | 0 |
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| Pro-survival role of gelsolin in mouse beta-cells | Diabetes | | | 2007 | 536 | 0 |
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| Dominant-negative effects of a novel mutated Ins2 allele causes early-onset diabetes and severe beta-cell loss in Munich Ins2C95S mutant mice | Diabetes | | | 2007 | 640 | 0 |
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| Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix | Diabetes | | | 2006 | 636 | 0 |
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| Diabetes research investment in the European Union | Nature medicine | | | 2006 | 579 | 0 |
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| Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat | Diabetes | | | 2006 | 1,035 | 0 |
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| Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway | Journal of cell science | | | 2006 | 602 | 298 |
|
| Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death | Diabetes | | | 2006 | 646 | 0 |
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| 10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it? | Diabetologia | | | 2005 | 495 | 0 |
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| Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells | The Journal of biological chemistry | | | 2005 | 546 | 238 |
|
| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | | | 2005 | 656 | 233 |
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| Sorting ourselves out: seeking consensus on trafficking in the beta-cell | Traffic | | | 2004 | 584 | 0 |
|
| Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways | Diabetes | | | 2004 | 654 | 780 |
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| Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide | Diabetes | | | 2004 | 555 | 0 |
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| Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications | Diabetologia | | | 2004 | 577 | 0 |
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| Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets | Proceedings of the National Academy of Sciences of the United States of America | | | 2004 | 622 | 0 |
|
| Towards a perfect beta cell replacement | Seminars in cell & developmental biology | | | 2004 | 556 | 0 |
|
| Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1beta | The Journal of clinical endocrinology and metabolism | | | 2004 | 624 | 0 |
|
| Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine | Nature cell biology | | | 2004 | 500 | 0 |
|
| Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis | The Journal of biological chemistry | | | 2003 | 619 | 0 |
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| Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse | Diabetes | | | 2003 | 567 | 0 |
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| Mutant proinsulin that cannot be converted is secreted efficiently from primary rat beta-cells via the regulated pathway | Molecular biology of the cell | | | 2003 | 578 | 0 |
|
| Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines | Endocrinology | | | 2003 | 544 | 1 |
|
| Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex | Molecular endocrinology | | | 2003 | 631 | 0 |
|
| Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription | Diabetologia | | | 2003 | 712 | 239 |
|
| Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion | Biochemical journal | | | 2002 | 656 | 0 |
|
| FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication | Proceedings of the National Academy of Sciences of the United States of America | | | 2002 | 836 | 328 |
|
| Truncated (des-[27-31]) C-peptide is not a major secretory product of human islets | Diabetologia | | | 2002 | 614 | 0 |
|
| Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets | The Journal of clinical investigation | | | 2002 | 871 | 342 |
|
| Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor | Journal of neurochemistry | | | 2002 | 585 | 0 |
|
| Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro | Diabetologia | | | 2002 | 881 | 0 |
|
| Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? | Diabetes | | | 2001 | 622 | 0 |
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| Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix | Diabetes | | | 2001 | 612 | 0 |
|
| NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro | Diabetologia | | | 2001 | 651 | 0 |
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| Role of clathrin in the regulated secretory pathway of pancreatic beta-cells | Journal of cell science | | | 2001 | 489 | 258 |
|
| Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells | Biochemical journal | | | 2001 | 584 | 0 |
|
| Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin | Diabetes | | | 2000 | 577 | 0 |
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| Sponsor, leader and lobbyist: the European Foundation for the Study of Diabetes (EFSD) and the future of diabetes research in Europe | Diabetologia | | | 2000 | 620 | 0 |
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| Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells | Diabetologia | | | 2000 | 645 | 0 |
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| Trafficking/sorting and granule biogenesis in the beta-cell | Seminars in cell & developmental biology | | | 2000 | 610 | 0 |
|
| Membrane localization and biological activity of SNAP-25 cysteine mutants in insulin-secreting cells | Journal of cell science | | | 2000 | 1,299 | 519 |
|
| SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion | Biochemical journal | | | 1999 | 554 | 0 |
|
| Storage of tissue-type plasminogen activator in Weibel-Palade bodies of human endothelial cells | Arteriosclerosis, thrombosis, and vascular biology | | | 1999 | 618 | 0 |
|
| Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1 | Journal of cell science | | | 1999 | 520 | 329 |
|
| Insulin resistance in HIV protease inhibitor-associated diabetes | Journal of acquired immune deficiency syndromes | | | 1999 | 703 | 0 |
|
| The GM2-1 ganglioside islet autoantigen in insulin-dependent diabetes mellitus is expressed in secretory granules and is not beta-cell specific | Endocrinology | | | 1998 | 570 | 0 |
|
| Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation | Diabetes | | | 1998 | 572 | 0 |
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| Sorting human beta-cells consequent to targeted expression of green fluorescent protein | Diabetes | | | 1998 | 810 | 0 |
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| Identification and characterization of alpha 3 beta 1 integrin on primary and transformed rat islet cells | Experimental cell research | | | 1997 | 601 | 0 |
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| Chronic central neuropeptide Y infusion in normal rats: status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia | Diabetologia | | | 1997 | 732 | 274 |
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| Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice | The Journal of biological chemistry | | | 1997 | 575 | 0 |
|
| Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression | Diabetes | | | 1997 | 651 | 0 |
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| Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1 | The Journal of biological chemistry | | | 1997 | 647 | 0 |
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| SNAP-25 can self-associate to form a disulfide-linked complex | Biological chemistry | | | 1997 | 627 | 0 |
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| Insulin production: from gene to granule | Diabetologia | | | 1997 | 550 | 0 |
|
| Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon | FEBS letters | | | 1997 | 602 | 0 |
|
| Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM | Diabetes | | | 1997 | 641 | 0 |
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| Proinsulin conversion in GH3 cells after coexpression of human proinsulin with the endoproteases PC2 and/or PC3 | Diabetes | | | 1997 | 578 | 0 |
|
| SNAP-23 is not cleaved by botulinum neurotoxin E and can replace SNAP-25 in the process of insulin secretion | The Journal of biological chemistry | | | 1997 | 652 | 0 |
|
| Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited | Proceedings of the National Academy of Sciences of the United States of America | | | 1996 | 624 | 0 |
|
| Des-(27-31)C-peptide. A novel secretory product of the rat pancreatic beta cell produced by truncation of proinsulin connecting peptide in secretory granules | The Journal of biological chemistry | | | 1996 | 627 | 0 |
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| Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis | EMBO journal | | | 1996 | 602 | 0 |
|
| Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus | Biochemical journal | | | 1996 | 555 | 0 |
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| Sequence requirements for proinsulin processing at the B-chain/C-peptide junction | Biochemical journal | | | 1995 | 629 | 0 |
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| SNAP-25 is expressed in islets of Langerhans and is involved in insulin release | The Journal of cell biology | | | 1995 | 595 | 0 |
|
| Processing of proinsulin by furin, PC2, and PC3 in (co) transfected COS (monkey kidney) cells | Diabetes | | | 1995 | 645 | 0 |
|
| Publish and flourish: seasonal advice to our readers | Diabetologia | | | 1995 | 588 | 0 |
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| Molecular strategies for the treatment of diabetes | Transplantation proceedings | | | 1994 | 550 | 0 |
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| Human proinsulin conversion in the regulated and the constitutive pathways of transfected AtT20 cells | The Journal of biological chemistry | | | 1994 | 570 | 0 |
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| Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells | Biochemical journal | | | 1994 | 590 | 0 |
|
| Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation | Journal of cell science | | | 1994 | 667 | 334 |
|
| Proinsulin processing in the regulated and the constitutive secretory pathway | Diabetologia | | | 1994 | 621 | 0 |
|
| Sorting and processing of secretory proteins | Biochemical journal | | | 1994 | 605 | 0 |
|
| pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle | The Journal of cell biology | | | 1994 | 657 | 0 |
|
| Hypoglycaemia caused by atypical insulin antibodies in a patient with benign monoclonal gammopathy | Journal of internal medicine | | | 1993 | 526 | 0 |
|
| Slow cleavage at the proinsulin B-chain/connecting peptide junction associated with low levels of endoprotease PC1/3 in transformed beta cells | The Journal of biological chemistry | | | 1993 | 569 | 0 |
|
| Kinetics of proinsulin conversion in human islets | Diabetes | | | 1993 | 564 | 0 |
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| Novel, non-crinophagic, degradation of connecting peptide in transformed pancreatic beta cells | The Journal of biological chemistry | | | 1993 | 522 | 0 |
|
| Substrate specificity of proinsulin conversion in the constitutive pathway of transfected FAO (hepatoma) cells | Diabetologia | | | 1993 | 591 | 0 |
|
| B-cell size influences glucose-stimulated insulin secretion | The American journal of physiology | | | 1993 | 600 | 0 |
|
| Tumor necrosis factor-alpha modifies adhesion properties of rat islet B cells | The Journal of clinical investigation | | | 1993 | 619 | 0 |
|
| Adaptation to supraphysiologic levels of insulin gene expression in transgenic mice: evidence for the importance of posttranscriptional regulation | The Journal of clinical investigation | | | 1993 | 643 | 0 |
|
| Processing of proinsulin by transfected hepatoma (FAO) cells | The Journal of biological chemistry | | | 1992 | 573 | 0 |
|
| The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs | Molecular and cellular endocrinology | | | 1992 | 642 | 0 |
|
| Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines | Endocrinology | | | 1992 | 902 | 0 |
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| Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II | Biochemical journal | | | 1991 | 597 | 0 |
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| Biosynthèse de l'insuline: trafic intracellulaire et transformations enzymatiques | Journées annuelles de diabétologie de l'Hôtel-Dieu | | | 1991 | 577 | 0 |
|
| Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic beta cell | Diabetologia | | | 1991 | 609 | 0 |
|
| Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types | Developmental biology | | | 1991 | 586 | 0 |
|
| Proinsulin conversion intermediates: a possible source of confusion | Diabetologia | | | 1991 | 574 | 0 |
|
| Heterogeneity of expression and secretion of native and mutant [AspB10]insulin in AtT20 cells | Molecular endocrinology | | | 1991 | 518 | 0 |
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| Proinsulin trafckin and processing in the pancreatic B cell | Trends in endocrinology and metabolism | | | 1990 | 600 | 0 |
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| Establishment and culture of insulin-secreting beta cell lines | Methods in enzymology | | | 1990 | 453 | 0 |
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| High-performance liquid chromatography analysis of circulating insulins distinguishes between endogenous insulin production (a potential pitfall with streptozotocin diabetic rats) and islet xenograft function | Diabetologia | | | 1990 | 596 | 0 |
|
| Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types | Experimental cell research | | | 1990 | 631 | 0 |
|
| Isolation of pancreatic islets and primary culture of the intact microorgans or of dispersed islet cells | Methods in enzymology | | | 1990 | 592 | 0 |
|
| Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells | Proceedings of the National Academy of Sciences of the United States of America | | | 1989 | 604 | 0 |
|
| Deletion of a highly conserved tetrapeptide sequence of the proinsulin connecting peptide (C-peptide) inhibits proinsulin to insulin conversion by transfected pituitary corticotroph (AtT20) cells | The Journal of biological chemistry | | | 1989 | 605 | 0 |
|
| Oxidation of rat insulin II, but not I, leads to anomalous elution profiles upon HPLC analysis of insulin-related peptides | FEBS letters | | | 1988 | 610 | 0 |
|
| Effects of aging on insulin synthesis and secretion. Differential effects on preproinsulin messenger RNA levels, proinsulin biosynthesis, and secretion of newly made and preformed insulin in the rat | The Journal of clinical investigation | | | 1988 | 668 | 0 |
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| Altered differentiated cell surface properties of transformed (RINm5F) compared with native adult rat pancreatic B cells | Endocrinology | | | 1988 | 636 | 0 |
|
| Islet B-cell dysfunction and the time course of recovery following chronic overinsulinisation of normal rats | Diabetologia | | | 1988 | 608 | 0 |
|
| The intracellular handling of insulin-related peptides in isolated pancreatic islets. Evidence for differential rates of degradation of insulin and C-peptide | Biochemical journal | | | 1988 | 575 | 0 |
|
| Newly synthesized proinsulin/insulin and stored insulin are released from pancreatic B cells predominantly via a regulated, rather than a constitutive, pathway | The Journal of cell biology | | | 1987 | 597 | 0 |
|
| Stimulation by ATP of proinsulin to insulin conversion in isolated rat pancreatic islet secretory granules. Association with the ATP-dependent proton pump | The Journal of biological chemistry | | | 1987 | 647 | 0 |
|
| Resistance of the insulin crystal to lysosomal proteases: implications for pancreatic B-cell crinophagy | Diabetologia | | | 1987 | 660 | 0 |
|
| Spontaneous reassociation of dispersed adult rat pancreatic islet cells into aggregates with three-dimensional architecture typical of native islets | Diabetes | | | 1987 | 729 | 0 |
|
| Tris(hydroxymethyl)aminomethane inhibits the synthesis and processing of proinsulin in isolated rat pancreatic islets without affecting release of insulin stores | Diabetes | | | 1986 | 648 | 0 |
|
| Identification of functional insulin receptors on membranes from an insulin-producing cell line (RINm5F) | Biochemical journal | | | 1985 | 560 | 0 |
|
| A new, rapid, method for preparation of dispersed pancreatic acini | Biochemical journal | | | 1985 | 546 | 0 |
|
| Nonconverted, amino acid analog-modified proinsulin stays in a Golgi-derived clathrin-coated membrane compartment | The Journal of cell biology | | | 1984 | 635 | 0 |
|
| Dispersed adult rat pancreatic islet cells in culture: A, B, and D cell function | Metabolism, clinical and experimental | | | 1984 | 719 | 0 |
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| Proinsulin modified by analogues of arginine and lysine is degraded rapidly in pancreatic B-cells | Biochemical journal | | | 1984 | 619 | 0 |
|
| A clathrin-coated, Golgi-related compartment of the insulin secreting cell accumulates proinsulin in the presence of monensin | Cell | | | 1984 | 647 | 0 |
|
| Insulin, not C-peptide (proinsulin), is present in crinophagic bodies of the pancreatic B-cell | The Journal of cell biology | | | 1984 | 662 | 0 |
|
| Elevated proinsulin biosynthesis in vitro from a rat model of non-insulin-dependent diabetes mellitus | Diabetes | | | 1983 | 602 | 0 |
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| In vivo modulation of gap junctions and dye coupling between B-cells of the intact pancreatic islet | Diabetes | | | 1983 | 572 | 0 |
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| Regulation of immunoreactive-insulin release from a rat cell line (RINm5F) | Biochemical journal | | | 1983 | 645 | 0 |
|
| Influence of glucose on insulin handling by rat islets in culture. A reflection of integrated changes in insulin biosynthesis, release, and intracellular degradation | Diabetes | | | 1983 | 618 | 0 |
|
| Abnormal glucose metabolism accompanies failure of glucose to stimulate insulin release from a rat pancreatic cell line (RINm5F) | Biochemical journal | | | 1983 | 587 | 0 |
|
| Differential rates of release of newly synthesized and of stored insulin from pancreatic islets | Endocrinology | | | 1982 | 626 | 0 |
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| The possible importance of contact between pancreatic islet cells for the control of insulin release | Endocrinology | | | 1982 | 648 | 0 |
|
| Inhibition of proinsulin to insulin conversion in rat islets using arginine and lysine analogs. Lack of effect on rate of release of modified products | The Journal of biological chemistry | | | 1982 | 566 | 0 |
|
| Functional differences between rat islets of ventral and dorsal pancreatic origin | The Journal of clinical investigation | | | 1982 | 645 | 0 |
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| Biologic activity and pharmacokinetics of biosynthetic human insulin in the rat | Diabetes care | | | 1981 | 623 | 0 |
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| Degradation of pork insulin and biosynthetic human insulin in vitro and in vivo: a comparative study | Endocrine research communications | | | 1981 | 592 | 0 |
|
| Insulin degradation by hepatocytes in primary culture | Endocrinology | | | 1981 | 653 | 0 |
|
| Increased clearance and degradation of [3H]insulin in streptozotocin diabetic rats | The Journal of clinical investigation | | | 1981 | 606 | 0 |
|
| In vitro studies on biosynthetic human insulin: an overview | Diabetes care | | | 1981 | 622 | 0 |
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| Internalization of 125I-insulin by IM-9 cultured human lymphocytes: a comparison between A14-monoiodo-pork and biosynthetic human insulin | Diabetes care | | | 1981 | 640 | 0 |
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| The effect of aprotinin on the absorption of subcutaneously injected regular insulin in normal subjects | Diabetes | | | 1980 | 681 | 0 |
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| Long-term exposure of isolated pancreatic islets to mannoheptulose: evidence for insulin degradation in the beta cell | Biochemical pharmacology | | | 1980 | 582 | 0 |
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| Gap junction development is correlated with insulin content in the pancreatic B cell | Science | | | 1980 | 534 | 0 |
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| In vitro and in vivo studies on glucagonoma tissue | Hormone and metabolic research | | | 1980 | 671 | 0 |
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| Intracellular degradation of insulin stores by rat pancreatic islets in vitro. An alternative pathway for homeostasis of pancreatic insulin content | The Journal of biological chemistry | | | 1980 | 567 | 0 |
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| Binding and degradation of semisynthetic tritiated insulin by IM-9 cultured human lymphocytes | Diabetes | | | 1980 | 652 | 0 |
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| Resistance against subcutaneous insulin successfully managed with aprotinin | Lancet | | | 1980 | 683 | 0 |
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| Pharmacokinetics of subcutaneously injected tritiated insulin: effects of exercise | Diabetes | | | 1979 | 610 | 0 |
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| Absorption kinetics of subcutaneously injected insulin. Evidence for degradation at the injection site | Diabetologia | | | 1979 | 610 | 0 |
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| Perturbation of hormone storage and release induced by cyproheptadine in rat pancreatic islets in vitro | Endocrinology | | | 1979 | 617 | 0 |
|
| Inhibition of degradation of insulin by ophthalamic acid and by a bovine pancreatic proteinase inhibitor | Biochemical journal | | | 1979 | 653 | 0 |
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| Distribution and metabolism of intravenously injected tritiated insulin in rats | Metabolism, clinical and experimental | | | 1979 | 607 | 0 |
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| Isolation of pancreatic islets of Langerhans by filtration on nylon mesh | Biochemical and biophysical research communications | | | 1978 | 648 | 0 |
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| Mobilization of subcutaneously injected tritiated insulin in rats: effects of muscular exercise | Diabetologia | | | 1978 | 644 | 0 |
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| The degradation of semisynthetic tritiated insulin by perfused mouse livers | Biochemical journal | | | 1976 | 599 | 0 |
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