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| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| IL-13 improves beta-cell survival and protects against IL-1beta-induced beta-cell death | Molecular metabolism |  | 2016 | 476 | 125 | ||
| Short Term Exposure of Beta Cells to Low Concentrations of Interleukin-1β Improves Insulin Secretion through Focal Adhesion and Actin Remodeling and Regulation of Gene Expression | The Journal of biological chemistry |  | 2015 | 518 | 2 | ||
| Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα | Molecular metabolism | | 2014 | 585 | 343 | ||
| β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment | Diabetes care | | 2014 | 769 | 617 | ||
| Expression, phosphorylation and function of the Rab-GTPase activating protein TBC1D1 in pancreatic beta-cells | FEBS letters | | 2014 | 703 | 348 | ||
| β-cell failure in type 2 diabetes: postulated mechanisms and prospects for prevention and treatment | The Journal of clinical endocrinology and metabolism | | 2014 | 612 | 807 | ||
| Regenerating 1 and 3b gene expression in the pancreas of type 2 diabetic Goto-Kakizaki (GK) rats | PloS one | | 2014 | 613 | 225 | ||
| Cardiotrophin 1 protects beta cells from apoptosis and prevents streptozotocin-induced diabetes in a mouse model | Diabetologia | | 2013 | 536 | 350 | ||
| Non-muscle myosin IIA is involved in focal adhesion and actin remodelling controlling glucose-stimulated insulin secretion | Diabetologia | | 2013 | 532 | 1 367 | ||
| Cell-type, allelic and genetic signatures in the human pancreatic beta cell transcriptome | Genome research | | 2013 | 630 | 444 | ||
| Autonomous and self-sustained circadian oscillators displayed in human islet cells | Diabetologia | | 2013 | 636 | 145 | ||
| A new paradigm for improved co-ordination and efficacy of European biomedical research: taking diabetes as a model | Diabetologia | | 2013 | 565 | 352 | ||
| In vitro proliferation of adult human beta-cells | PloS one | | 2012 | 656 | 397 | ||
| Bimodal impact of skeletal muscle on pancreatic β-cell function in health and disease | Diabetes, obesity & metabolism | | 2012 | 617 | 669 | ||
| Novel mechanistic link between focal adhesion remodeling and glucose-stimulated insulin secretion | The Journal of biological chemistry | | 2012 | 622 | 382 | ||
| Focal adhesion remodeling is crucial for glucose-stimulated insulin secretion and involves activation of focal adhesion kinase and paxillin | Diabetes | | 2011 | 559 | 284 | ||
| Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto-Kakizaki (GK) rat | Diabetologia | | 2011 | 612 | 356 | ||
| Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle | Diabetes | | 2011 | 579 | 2 | ||
| Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells | Nature medicine | | 2011 | 755 | 718 | ||
| Prime time for DIAMAP: a road map for diabetes research in Europe | Diabetologia | | 2010 | 472 | 147 | ||
| Cytokine production by islets in health and diabetes: cellular origin, regulation and function | Trends in endocrinology and metabolism | | 2010 | 475 | 1 | ||
| Current status of islet cell replacement and regeneration therapy | The Journal of clinical endocrinology and metabolism | | 2010 | 549 | 0 | ||
| Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate | Traffic | | 2010 | 504 | 0 | ||
| Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion | The Journal of biological chemistry | | 2009 | 574 | 0 | ||
| Signaling pathways implicated in the stimulation of beta-cell proliferation by extracellular matrix | Molecular endocrinology | | 2009 | 503 | 0 | ||
| Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function | Endocrinology | | 2009 | 599 | 0 | ||
| Order! Order! Order in the House! DIAMAP: a road map for European diabetes research | Diabetologia | | 2008 | 486 | 94 | ||
| Small interfering RNA-mediated suppression of proislet amyloid polypeptide expression inhibits islet amyloid formation and enhances survival of human islets in culture | Diabetes | | 2008 | 559 | 0 | ||
| Interleukin-6 regulates pancreatic alpha-cell mass expansion | Proceedings of the National Academy of Sciences of the United States of America | | 2008 | 521 | 0 | ||
| Proliferation of sorted human and rat beta cells | Diabetologia | | 2008 | 764 | 169 | ||
| The right stuff: beta-cell channels, cycles, and sensors | American journal of physiology: endocrinology and metabolism | | 2008 | 498 | 0 | ||
| Munc 18-1 and granuphilin collaborate during insulin granule exocytosis | Traffic | | 2008 | 624 | 0 | ||
| Cell therapy for type 2 diabetes: is it desirable and can we get it? | Diabetes, obesity & metabolism | | 2008 | 553 | 0 | ||
| Rab GTPase-activating protein AS160 is a major downstream effector of protein kinase B/Akt signaling in pancreatic beta-cells | Diabetes | | 2008 | 555 | 0 | ||
| Increased interleukin (IL)-1beta messenger ribonucleic acid expression in beta -cells of individuals with type 2 diabetes and regulation of IL-1beta in human islets by glucose and autostimulation | The Journal of clinical endocrinology and metabolism | | 2008 | 573 | 252 | ||
| Increasing GLP-1-induced beta-cell proliferation by silencing the negative regulators of signaling cAMP response element modulator-alpha and DUSP14 | Diabetes | | 2008 | 509 | 1 403 | ||
| Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion | Endocrinology | | 2008 | 586 | 0 | ||
| Dynamin is functionally coupled to insulin granule exocytosis | The Journal of biological chemistry | | 2007 | 566 | 0 | ||
| Induction of CXCL1 by extracellular matrix and autocrine enhancement by interleukin-1 in rat pancreatic beta-cells | Endocrinology | | 2007 | 497 | 0 | ||
| The innovative medicines initiative (IMI): a shot in the arm for European diabetes research? | Diabetologia | | 2007 | 547 | 143 | ||
| The Fas pathway is involved in pancreatic beta cell secretory function | Proceedings of the National Academy of Sciences of the United States of America | | 2007 | 591 | 0 | ||
| Differential expression of E-cadherin at the surface of rat beta-cells as a marker of functional heterogeneity | Journal of Endocrinology | | 2007 | 524 | 0 | ||
| Comment faire renaître la cellule beta du sacrifice en sauveur | Journées annuelles de diabétologie de l'Hôtel-Dieu | 2007 | 433 | 0 | |||
| Pro-survival role of gelsolin in mouse beta-cells | Diabetes | | 2007 | 462 | 0 | ||
| Dominant-negative effects of a novel mutated Ins2 allele causes early-onset diabetes and severe beta-cell loss in Munich Ins2C95S mutant mice | Diabetes | | 2007 | 554 | 0 | ||
| Blockade of beta1 integrin-laminin-5 interaction affects spreading and insulin secretion of rat beta-cells attached on extracellular matrix | Diabetes | | 2006 | 554 | 0 | ||
| Diabetes research investment in the European Union | Nature medicine | | 2006 | 532 | 0 | ||
| Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat | Diabetes | | 2006 | 960 | 0 | ||
| Regulation of pancreatic beta-cell insulin secretion by actin cytoskeleton remodelling: role of gelsolin and cooperation with the MAPK signalling pathway | Journal of cell science | | 2006 | 517 | 182 | ||
| Impaired NH2-terminal processing of human proislet amyloid polypeptide by the prohormone convertase PC2 leads to amyloid formation and cell death | Diabetes | | 2006 | 564 | 0 | ||
| 10th EASD/JDRF Oxford Workshop. What is a beta-cell and can we improve it? | Diabetologia | | 2005 | 440 | 0 | ||
| Activation of NF-kappaB by extracellular matrix is involved in spreading and glucose-stimulated insulin secretion of pancreatic beta cells | The Journal of biological chemistry | | 2005 | 464 | 154 | ||
| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | | 2005 | 587 | 147 | ||
| Sorting ourselves out: seeking consensus on trafficking in the beta-cell | Traffic | | 2004 | 446 | 0 | ||
| Extracellular matrix protects pancreatic beta-cells against apoptosis: role of short- and long-term signaling pathways | Diabetes | | 2004 | 568 | 593 | ||
| Role of beta-cell prohormone convertase (PC)1/3 in processing of pro-islet amyloid polypeptide | Diabetes | | 2004 | 467 | 0 | ||
| Decreased beta-cell mass in diabetes: significance, mechanisms and therapeutic implications | Diabetologia | | 2004 | 513 | 0 | ||
| Leptin modulates beta cell expression of IL-1 receptor antagonist and release of IL-1beta in human islets | Proceedings of the National Academy of Sciences of the United States of America | | 2004 | 532 | 0 | ||
| Towards a perfect beta cell replacement | Seminars in cell & developmental biology | | 2004 | 505 | 0 | ||
| Pioglitazone and sodium salicylate protect human beta-cells against apoptosis and impaired function induced by glucose and interleukin-1beta | The Journal of clinical endocrinology and metabolism | | 2004 | 544 | 0 | ||
| Cellular sources of new pancreatic beta cells and therapeutic implications for regenerative medicine | Nature cell biology | | 2004 | 425 | 0 | ||
| Glucagon-like peptide-1 receptor signaling modulates beta cell apoptosis | The Journal of biological chemistry | | 2003 | 498 | 0 | ||
| Dominant negative pathogenesis by mutant proinsulin in the Akita diabetic mouse | Diabetes | | 2003 | 497 | 0 | ||
| Mutant proinsulin that cannot be converted is secreted efficiently from primary rat beta-cells via the regulated pathway | Molecular biology of the cell | | 2003 | 506 | 0 | ||
| Differential gene expression in well-regulated and dysregulated pancreatic beta-cell (MIN6) sublines | Endocrinology | | 2003 | 460 | 1 | ||
| Glucose-stimulated insulin secretion is coupled to the interaction of actin with the t-SNARE (target membrane soluble N-ethylmaleimide-sensitive factor attachment protein receptor protein) complex | Molecular endocrinology | | 2003 | 555 | 0 | ||
| Ectopic expression of the beta-cell specific transcription factor Pdx1 inhibits glucagon gene transcription | Diabetologia | | 2003 | 610 | 136 | ||
| Phosphorylation of SNAP-25 on serine-187 is induced by secretagogues in insulin-secreting cells, but is not correlated with insulin secretion | Biochemical journal | | 2002 | 551 | 0 | ||
| FLIP switches Fas-mediated glucose signaling in human pancreatic beta cells from apoptosis to cell replication | Proceedings of the National Academy of Sciences of the United States of America | | 2002 | 679 | 199 | ||
| Truncated (des-[27-31]) C-peptide is not a major secretory product of human islets | Diabetologia | | 2002 | 529 | 0 | ||
| Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets | The Journal of clinical investigation | | 2002 | 705 | 185 | ||
| Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor | Journal of neurochemistry | | 2002 | 508 | 0 | ||
| Impact of integrin-matrix matching and inhibition of apoptosis on the survival of purified human beta-cells in vitro | Diabetologia | | 2002 | 722 | 0 | ||
| Gene and cell-replacement therapy in the treatment of type 1 diabetes: how high must the standards be set? | Diabetes | | 2001 | 542 | 0 | ||
| Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix | Diabetes | | 2001 | 550 | 0 | ||
| NGF-withdrawal induces apoptosis in pancreatic beta cells in vitro | Diabetologia | | 2001 | 560 | 0 | ||
| Role of clathrin in the regulated secretory pathway of pancreatic beta-cells | Journal of cell science | | 2001 | 411 | 58 | ||
| Oligomerization of green fluorescent protein in the secretory pathway of endocrine cells | Biochemical journal | | 2001 | 516 | 0 | ||
| Importance of cell-matrix interactions in rat islet beta-cell secretion in vitro: role of alpha6beta1 integrin | Diabetes | | 2000 | 506 | 0 | ||
| Sponsor, leader and lobbyist: the European Foundation for the Study of Diabetes (EFSD) and the future of diabetes research in Europe | Diabetologia | | 2000 | 558 | 0 | ||
| Trafficking of non-regulated secretory proteins in insulin secreting (INS-1) cells | Diabetologia | | 2000 | 547 | 0 | ||
| Trafficking/sorting and granule biogenesis in the beta-cell | Seminars in cell & developmental biology | | 2000 | 541 | 0 | ||
| Membrane localization and biological activity of SNAP-25 cysteine mutants in insulin-secreting cells | Journal of cell science | | 2000 | 1 100 | 243 | ||
| SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion | Biochemical journal | | 1999 | 475 | 0 | ||
| Storage of tissue-type plasminogen activator in Weibel-Palade bodies of human endothelial cells | Arteriosclerosis, thrombosis, and vascular biology | | 1999 | 552 | 0 | ||
| Blockade of membrane transport and disassembly of the Golgi complex by expression of syntaxin 1A in neurosecretion-incompetent cells: prevention by rbSEC1 | Journal of cell science | | 1999 | 437 | 175 | ||
| Insulin resistance in HIV protease inhibitor-associated diabetes | Journal of acquired immune deficiency syndromes | 1999 | 609 | 0 | |||
| The GM2-1 ganglioside islet autoantigen in insulin-dependent diabetes mellitus is expressed in secretory granules and is not beta-cell specific | Endocrinology | | 1998 | 491 | 0 | ||
| Vascularization of purified pancreatic islet-like cell aggregates (pseudoislets) after syngeneic transplantation | Diabetes | | 1998 | 514 | 0 | ||
| Sorting human beta-cells consequent to targeted expression of green fluorescent protein | Diabetes | | 1998 | 676 | 0 | ||
| Identification and characterization of alpha 3 beta 1 integrin on primary and transformed rat islet cells | Experimental cell research | | 1997 | 520 | 0 | ||
| Chronic central neuropeptide Y infusion in normal rats: status of the hypothalamo-pituitary-adrenal axis, and vagal mediation of hyperinsulinaemia | Diabetologia | | 1997 | 659 | 166 | ||
| Proinsulin targeting to the regulated pathway is not impaired in carboxypeptidase E-deficient Cpefat/Cpefat mice | The Journal of biological chemistry | | 1997 | 504 | 0 | ||
| Novel insulinoma cell lines produced by iterative engineering of GLUT2, glucokinase, and human insulin expression | Diabetes | 1997 | 561 | 0 | |||
| Role of the prohormone convertase PC3 in the processing of proglucagon to glucagon-like peptide 1 | The Journal of biological chemistry | | 1997 | 575 | 0 | ||
| SNAP-25 can self-associate to form a disulfide-linked complex | Biological chemistry | 1997 | 505 | 0 | |||
| Insulin production: from gene to granule | Diabetologia | | 1997 | 485 | 0 | ||
| Role of the prohormone convertase PC2 in the processing of proglucagon to glucagon | FEBS letters | | 1997 | 551 | 0 | ||
| Release of incompletely processed proinsulin is the cause of the disproportionate proinsulinemia of NIDDM | Diabetes | 1997 | 560 | 0 | |||
| Proinsulin conversion in GH3 cells after coexpression of human proinsulin with the endoproteases PC2 and/or PC3 | Diabetes | 1997 | 501 | 0 | |||
| SNAP-23 is not cleaved by botulinum neurotoxin E and can replace SNAP-25 in the process of insulin secretion | The Journal of biological chemistry | | 1997 | 568 | 0 | ||
| Inositol 1,4,5-trisphosphate receptor subtype 3 in pancreatic islet cell secretory granules revisited | Proceedings of the National Academy of Sciences of the United States of America | | 1996 | 549 | 0 | ||
| Des-(27-31)C-peptide. A novel secretory product of the rat pancreatic beta cell produced by truncation of proinsulin connecting peptide in secretory granules | The Journal of biological chemistry | | 1996 | 540 | 0 | ||
| Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis | EMBO journal | | 1996 | 489 | 0 | ||
| Proinsulin processing in the rat insulinoma cell line INS after overexpression of the endoproteases PC2 or PC3 by recombinant adenovirus | Biochemical journal | | 1996 | 484 | 0 | ||
| Sequence requirements for proinsulin processing at the B-chain/C-peptide junction | Biochemical journal | | 1995 | 543 | 0 | ||
| SNAP-25 is expressed in islets of Langerhans and is involved in insulin release | The Journal of cell biology | | 1995 | 521 | 0 | ||
| Processing of proinsulin by furin, PC2, and PC3 in (co) transfected COS (monkey kidney) cells | Diabetes | 1995 | 562 | 0 | |||
| Publish and flourish: seasonal advice to our readers | Diabetologia | 1995 | 538 | 0 | |||
| Molecular strategies for the treatment of diabetes | Transplantation proceedings | 1994 | 480 | 0 | |||
| Human proinsulin conversion in the regulated and the constitutive pathways of transfected AtT20 cells | The Journal of biological chemistry | | 1994 | 509 | 0 | ||
| Levels of the conversion endoproteases PC1 (PC3) and PC2 distinguish between insulin-producing pancreatic islet beta cells and non-beta cells | Biochemical journal | | 1994 | 515 | 0 | ||
| Expression of neural cell adhesion molecule (N-CAM) in rat islets and its role in islet cell type segregation | Journal of cell science | | 1994 | 439 | 141 | ||
| Proinsulin processing in the regulated and the constitutive secretory pathway | Diabetologia | 1994 | 556 | 0 | |||
| Sorting and processing of secretory proteins | Biochemical journal | | 1994 | 542 | 0 | ||
| pH-independent and -dependent cleavage of proinsulin in the same secretory vesicle | The Journal of cell biology | | 1994 | 582 | 0 | ||
| Hypoglycaemia caused by atypical insulin antibodies in a patient with benign monoclonal gammopathy | Journal of internal medicine | 1993 | 448 | 0 | |||
| Slow cleavage at the proinsulin B-chain/connecting peptide junction associated with low levels of endoprotease PC1/3 in transformed beta cells | The Journal of biological chemistry | | 1993 | 503 | 0 | ||
| Kinetics of proinsulin conversion in human islets | Diabetes | 1993 | 488 | 0 | |||
| Novel, non-crinophagic, degradation of connecting peptide in transformed pancreatic beta cells | The Journal of biological chemistry | | 1993 | 429 | 0 | ||
| Substrate specificity of proinsulin conversion in the constitutive pathway of transfected FAO (hepatoma) cells | Diabetologia | 1993 | 514 | 0 | |||
| B-cell size influences glucose-stimulated insulin secretion | The American journal of physiology | | 1993 | 542 | 0 | ||
| Tumor necrosis factor-alpha modifies adhesion properties of rat islet B cells | The Journal of clinical investigation | | 1993 | 554 | 0 | ||
| Adaptation to supraphysiologic levels of insulin gene expression in transgenic mice: evidence for the importance of posttranscriptional regulation | The Journal of clinical investigation | | 1993 | 576 | 0 | ||
| Processing of proinsulin by transfected hepatoma (FAO) cells | The Journal of biological chemistry | | 1992 | 502 | 0 | ||
| The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs | Molecular and cellular endocrinology | 1992 | 575 | 0 | |||
| Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines | Endocrinology | 1992 | 752 | 0 | |||
| Differential rates of conversion of rat proinsulins I and II. Evidence for slow cleavage at the B-chain/C-peptide junction of proinsulin II | Biochemical journal | | 1991 | 529 | 0 | ||
| Biosynthèse de l'insuline: trafic intracellulaire et transformations enzymatiques | Journées annuelles de diabétologie de l'Hôtel-Dieu | 1991 | 505 | 0 | |||
| Structural domains and molecular lifestyles of insulin and its precursors in the pancreatic beta cell | Diabetologia | 1991 | 541 | 0 | |||
| Uvomorulin mediates calcium-dependent aggregation of islet cells, whereas calcium-independent cell adhesion molecules distinguish between islet cell types | Developmental biology | 1991 | 512 | 0 | |||
| Proinsulin conversion intermediates: a possible source of confusion | Diabetologia | 1991 | 519 | 0 | |||
| Heterogeneity of expression and secretion of native and mutant [AspB10]insulin in AtT20 cells | Molecular endocrinology | 1991 | 438 | 0 | |||
| Proinsulin trafckin and processing in the pancreatic B cell | Trends in endocrinology and metabolism | 1990 | 536 | 0 | |||
| Establishment and culture of insulin-secreting beta cell lines | Methods in enzymology | 1990 | 402 | 0 | |||
| High-performance liquid chromatography analysis of circulating insulins distinguishes between endogenous insulin production (a potential pitfall with streptozotocin diabetic rats) and islet xenograft function | Diabetologia | 1990 | 534 | 0 | |||
| Differences in aggregation properties and levels of the neural cell adhesion molecule (NCAM) between islet cell types | Experimental cell research | 1990 | 545 | 0 | |||
| Isolation of pancreatic islets and primary culture of the intact microorgans or of dispersed islet cells | Methods in enzymology | 1990 | 525 | 0 | |||
| Partial diversion of a mutant proinsulin (B10 aspartic acid) from the regulated to the constitutive secretory pathway in transfected AtT-20 cells | Proceedings of the National Academy of Sciences of the United States of America | | 1989 | 531 | 0 |