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Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity* |
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Published in | HIV medicine. 2012, vol. 13, no. 1, p. 54-61 | |
Abstract | HIV-infected children have impaired antibody responses after exposure to certain antigens. Our aim was to determine whether HIV-infected children had lower varicella zoster virus (VZV) antibody levels compared with HIV-infected adults or healthy children and, if so, whether this was attributable to an impaired primary response, accelerated antibody loss, or failure to reactivate the memory VZV response. | |
Keywords | Adolescent — Antibodies, Viral/blood/immunology — Antibody Affinity/immunology — Child — Child, Preschool — Enzyme-Linked Immunosorbent Assay — Epidemiologic Methods — Female — HIV Infections/immunology — Herpesvirus 3, Human/immunology — Humans — Immunoglobulin G/blood/immunology — Immunologic Memory/immunology — Male — Switzerland | |
Identifiers | PMID: 21722287 | |
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Research groups | Centre de Vaccinologie et d'Immunologie néonatale (177) Recherche en infectiologie pédiatrique et en pédiatrie générale (853) | |
Citation (ISO format) | L'HUILLIER, Arnaud et al. Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity*. In: HIV medicine, 2012, vol. 13, n° 1, p. 54-61. doi: 10.1111/j.1468-1293.2011.00936.x https://archive-ouverte.unige.ch/unige:31713 |