Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity*

L'Huillier, Arnaud; Ferry, T; Courvoisier, Delphine; Aebi, Christoph; Cheseaux, Jean-Jacques; Kind, C; Rudin, C; Nadal, D; Hirschel, Bernard; Sottas, Cédric Ernest; Siegrist, Claire-Anne; Posfay Barbe, Klara

doi:10.1111/j.1468-1293.2011.00936.x

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Title		Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity*
Authors		L'Huillier, Arnaud Ferry, T Courvoisier, Delphine Aebi, Christoph Cheseaux, Jean-Jacques Kind, C Rudin, C Nadal, D Hirschel, Bernard Sottas, Cédric Ernest Siegrist, Claire-Anne Posfay Barbe, Klara show all authors [1 - 12]
Published in		HIV medicine. 2012, vol. 13, no. 1, p. 54-61
Abstract		HIV-infected children have impaired antibody responses after exposure to certain antigens. Our aim was to determine whether HIV-infected children had lower varicella zoster virus (VZV) antibody levels compared with HIV-infected adults or healthy children and, if so, whether this was attributable to an impaired primary response, accelerated antibody loss, or failure to reactivate the memory VZV response.
Keywords		Adolescent — Antibodies, Viral/blood/immunology — Antibody Affinity/immunology — Child — Child, Preschool — Enzyme-Linked Immunosorbent Assay — Epidemiologic Methods — Female — HIV Infections/immunology — Herpesvirus 3, Human/immunology — Humans — Immunoglobulin G/blood/immunology — Immunologic Memory/immunology — Male — Switzerland
Identifiers		DOI: 10.1111/j.1468-1293.2011.00936.x PMID: 21722287
Full text		Article (Published version) (208 Kb) - Limited access to UNIGE
Structures		Faculté de médecine / Section de médecine clinique / Département de pédiatrie, gynécologie et obstétrique
Research groups		Centre de Vaccinologie et d'Immunologie néonatale (177) Recherche en infectiologie pédiatrique et en pédiatrie générale (853)
Citation (ISO format)		L'HUILLIER, Arnaud et al. Impaired antibody memory to varicella zoster virus in HIV-infected children: low antibody levels and avidity*. In: HIV medicine, 2012, vol. 13, n° 1, p. 54-61. doi: 10.1111/j.1468-1293.2011.00936.x https://archive-ouverte.unige.ch/unige:31713