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Master
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High Yield Expression and Purification of mature TNF-α by SUMO-Fusion Technology

Master program titleMaster in Pharmacy - Travail personnel de recherche
Defense date2013
Abstract

Inflammatory bowel disease (IBD) is an autoimmune disease of the gastrointestinal tract. It is a set of chronic inflammatory conditions resulting from inappropriate activation of the mucosal immune system. The two main types of IBDs are Crohn's disease (CD) and ulcerative colitis (UC). TNF-­‐α is a proinflammatory cytokine and therefore a target for IBD treatment. The actual inhibitors of TNF-­‐α are Infliximab, Adalimumab and Certolizumab pegol. The latter are monoclonal antibodies and present safety issues.

eng
Citation (ISO format)
BOUNNACEUR, Shahrazade. High Yield Expression and Purification of mature TNF-α by SUMO-Fusion Technology. 2013.
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Master thesis
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Identifiers
  • PID : unige:31570
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Technical informations

Creation11/26/2013 2:05:00 PM
First validation11/26/2013 2:05:00 PM
Update time03/14/2023 8:39:40 PM
Status update03/14/2023 8:39:39 PM
Last indexation01/29/2024 8:00:28 PM
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