| A Spinster-like Transporter at the Inner Membrane Complex is critical for Toxoplasma gondii cytokinesis, motility and invasion | PLOS pathogens |  | | 2026 | 36 | 22 |
|
| Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model | Pharmaceutics | | | 2024 | 128 | 275 |
|
| Effects of a diverse prebiotic fibre supplement on HbA1c, insulin sensitivity and inflammatory biomarkers in pre-diabetes: a pilot placebo-controlled randomised clinical trial | British journal of nutrition |  | | 2024 | 1 | 0 |
|
| Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes | PloS one | | | 2024 | 59 | 213 |
|
| Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1 | Nature communications | | | 2023 | 105 | 269 |
|
| Targeted Nanofitin-drug Conjugates Achieve Efficient Tumor Delivery and Therapeutic Effect in an EGFRpos Mouse Xenograft Model | Molecular cancer therapeutics | | | 2023 | 77 | 230 |
|
| Challenges and Opportunities in the Oral Delivery of Recombinant Biologics | Pharmaceutics | | | 2023 | 50 | 67 |
|
| CEMIP ( HYBID , KIAA1199 ): structure, function and expression in health and disease | The FEBS journal | | | 2022 | 188 | 355 |
|
| Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases | Scientific reports | | | 2022 | 288 | 156 |
|
| 5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells | PloS one | | | 2022 | 89 | 179 |
|
| Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea pers | Frontiers in chemistry | | | 2022 | 242 | 231 |
|
| Using protease inhibitors to improve protein stability in the presence of skin: A case study on the stability of insulin like growth factor 1 | European journal of pharmaceutics and biopharmaceutics | | | 2021 | 1 | 5 |
|
| Functional and anatomical characterization of atrophic age-related macular degeneration in an aged mouse model | Journal of Ophthalmology and Research | | | 2021 | 465 | 399 |
|
| Glomerular macrophages in human auto- and allo-immune nephritis | Cells | | | 2021 | 253 | 208 |
|
| Heat-stability study of various insulin types in tropical temperature conditions: new insights towards improving diabetes care | PLOS ONE | | | 2021 | 396 | 535 |
|
| Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation | Frontiers in pharmacology | | | 2021 | 154 | 373 |
|
| From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation | Frontiers in Chemistry | | | 2021 | 510 | 1,195 |
|
| Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6 | Cells | | | 2020 | 370 | 213 |
|
| Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host models | Frontiers in Microbiology | | | 2020 | 333 | 234 |
|
| Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33 | Journal of Biological Chemistry | | | 2020 | 303 | 217 |
|
| Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer | Biochimica et Biophysica Acta. Reviews on Cancer | | | 2019 | 494 | 1,648 |
|
| DDR1 role in fibrosis and its pharmacological targeting | Biochimica et Biophysica Acta - Molecular Cell Research | | | 2019 | 437 | 3 |
|
| Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models | | | | 2018 | 655 | 410 |
|
| Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module | Molecular Cell | | | 2018 | 480 | 0 |
|
| Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets | Scientific Reports | | | 2018 | 567 | 296 |
|
| Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy | Nature Communications | | | 2018 | 516 | 389 |
|
| Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes | Nature communications | | | 2018 | 2 | 3 |
|
| Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases | EMBO Journal | | | 2018 | 684 | 15 |
|
| Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model | PLOS ONE | | | 2017 | 500 | 296 |
|
| Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks | Molecular cell | | | 2016 | 71 | 214 |
|
| In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA | Journal of medicinal chemistry | | | 2016 | 680 | 6 |
|
| A subset of N-substituted phenothiazines inhibits NADPH oxidases | Free radical biology & medicine | | | 2015 | 604 | 692 |
|
| A novel biocompatible hyaluronic acid-chitosan hybrid hydrogel for osteoarthrosis therapy | International journal of pharmaceutics | | | 2015 | 912 | 2 |
|
| Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila | ACS infectious diseases | | | 2015 | 694 | 556 |
|
| Adrenergic antagonists restrict replication of Legionella | Microbiology | | | 2015 | 623 | 0 |
|
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | | | 2014 | 725 | 820 |
|
| Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system | PloS one | | | 2014 | 773 | 367 |
|
| Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle | PloS one | | | 2014 | 634 | 659 |
|
| Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [18F]FPPA-c(RGDfK) | Bioorganic & medicinal chemistry letters | | | 2013 | 705 | 0 |
|
| The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery | Chimia | | | 2012 | 847 | 894 |
|
| NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action | British journal of pharmacology | | | 2011 | 752 | 0 |
|
| Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor | Molecular pharmaceutics | | | 2011 | 635 | 2 |
|
| Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | Antioxidants & redox signaling | | | 2009 | 682 | 2 |
|
| Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors | Journal of chromatography. B | | | 2007 | 549 | 1 |
|
| Synthesis, in vitro and in silico assessment of organometallic Rhenium(I) and Technetium(I) thymidine complexes | Journal of organometallic chemistry | | | 2007 | 622 | 0 |
|
| Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | Biochemical journal | | | 2006 | 503 | 0 |
|
| Inhibition of RET tyrosine kinase by SU5416 | Journal of molecular endocrinology | | | 2006 | 129 | 0 |
|
| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis | Nature cell biology | | | 2006 | 94 | 0 |
|
| Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling | Journal of medicinal chemistry | | | 2006 | 138 | 0 |
|
| Inhibition of Plasmodium falciparum Fatty Acid Biosynthesis: Evaluation of FabG, FabZ, and FabI as Drug Targets for Flavonoids | Journal of medicinal chemistry | | | 2006 | 198 | 1 |
|
| Tyrosine kinase drug discovery: what can be learned from solved crystal structures? | ARKIVOC | | | 2006 | 564 | 467 |
|
| In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells | Cancer research | | | 2006 | 529 | 1 |
|
| High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics | Protein expression and purification | | | 2006 | 73 | 0 |
|
| Recombinant expression and biochemical characterization of the unique elongating β-Ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates | The Journal of biological chemistry | | | 2006 | 171 | 138 |
|
| Abl inhibitor BMS354825 binding mode in Abelson kinase revealed by molecular docking studies | Leukemia | | | 2005 | 128 | 0 |
|
| An enzyme-linked immunosorbent assay to screen for inhibitors of the oncogenic anaplastic lymphoma kinase | Haematologica | | | 2005 | 439 | 214 |
|
| The crystal structure of PfFabZ, the unique β‐hydroxyacyl‐ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum | Protein science | | | 2005 | 83 | 223 |
|
| Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity | Biochemistry | | | 2005 | 564 | 0 |
|
