| A Spinster-like Transporter at the Inner Membrane Complex is critical for Toxoplasma gondii cytokinesis, motility and invasion | PLOS pathogens |  | | 2026 | 46 | 41 |
|
| Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model | Pharmaceutics | | | 2024 | 132 | 301 |
|
| Effects of a diverse prebiotic fibre supplement on HbA1c, insulin sensitivity and inflammatory biomarkers in pre-diabetes: a pilot placebo-controlled randomised clinical trial | British journal of nutrition |  | | 2024 | 5 | 0 |
|
| Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes | PloS one | | | 2024 | 64 | 248 |
|
| Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1 | Nature communications | | | 2023 | 110 | 298 |
|
| Targeted Nanofitin-drug Conjugates Achieve Efficient Tumor Delivery and Therapeutic Effect in an EGFRpos Mouse Xenograft Model | Molecular cancer therapeutics | | | 2023 | 81 | 263 |
|
| Challenges and Opportunities in the Oral Delivery of Recombinant Biologics | Pharmaceutics | | | 2023 | 54 | 77 |
|
| CEMIP ( HYBID , KIAA1199 ): structure, function and expression in health and disease | The FEBS journal | | | 2022 | 193 | 376 |
|
| Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases | Scientific reports | | | 2022 | 293 | 169 |
|
| 5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells | PloS one | | | 2022 | 93 | 191 |
|
| Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea pers | Frontiers in chemistry | | | 2022 | 247 | 251 |
|
| Using protease inhibitors to improve protein stability in the presence of skin: A case study on the stability of insulin like growth factor 1 | European journal of pharmaceutics and biopharmaceutics | | | 2021 | 5 | 14 |
|
| Functional and anatomical characterization of atrophic age-related macular degeneration in an aged mouse model | Journal of Ophthalmology and Research | | | 2021 | 469 | 410 |
|
| Glomerular macrophages in human auto- and allo-immune nephritis | Cells | | | 2021 | 258 | 219 |
|
| Heat-stability study of various insulin types in tropical temperature conditions: new insights towards improving diabetes care | PLOS ONE | | | 2021 | 401 | 555 |
|
| Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation | Frontiers in pharmacology | | | 2021 | 158 | 419 |
|
| From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation | Frontiers in Chemistry | | | 2021 | 514 | 1,244 |
|
| Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6 | Cells | | | 2020 | 374 | 218 |
|
| Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host models | Frontiers in Microbiology | | | 2020 | 337 | 238 |
|
| Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33 | Journal of Biological Chemistry | | | 2020 | 307 | 223 |
|
| Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer | Biochimica et Biophysica Acta. Reviews on Cancer | | | 2019 | 499 | 1,705 |
|
| DDR1 role in fibrosis and its pharmacological targeting | Biochimica et Biophysica Acta - Molecular Cell Research | | | 2019 | 443 | 3 |
|
| Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models | | | | 2018 | 659 | 414 |
|
| Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module | Molecular Cell | | | 2018 | 489 | 0 |
|
| Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets | Scientific Reports | | | 2018 | 571 | 302 |
|
| Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy | Nature Communications | | | 2018 | 523 | 400 |
|
| Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes | Nature communications | | | 2018 | 6 | 10 |
|
| Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases | EMBO Journal | | | 2018 | 688 | 15 |
|
| Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model | PLOS ONE | | | 2017 | 504 | 304 |
|
| Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks | Molecular cell | | | 2016 | 75 | 226 |
|
| In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA | Journal of medicinal chemistry | | | 2016 | 686 | 6 |
|
| A subset of N-substituted phenothiazines inhibits NADPH oxidases | Free radical biology & medicine | | | 2015 | 611 | 704 |
|
| A novel biocompatible hyaluronic acid-chitosan hybrid hydrogel for osteoarthrosis therapy | International journal of pharmaceutics | | | 2015 | 919 | 2 |
|
| Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila | ACS infectious diseases | | | 2015 | 701 | 561 |
|
| Adrenergic antagonists restrict replication of Legionella | Microbiology | | | 2015 | 630 | 0 |
|
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | | | 2014 | 732 | 855 |
|
| Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system | PloS one | | | 2014 | 780 | 376 |
|
| Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle | PloS one | | | 2014 | 640 | 665 |
|
| Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [18F]FPPA-c(RGDfK) | Bioorganic & medicinal chemistry letters | | | 2013 | 712 | 0 |
|
| The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery | Chimia | | | 2012 | 853 | 916 |
|
| NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action | British journal of pharmacology | | | 2011 | 758 | 0 |
|
| Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor | Molecular pharmaceutics | | | 2011 | 641 | 2 |
|
| Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | Antioxidants & redox signaling | | | 2009 | 688 | 2 |
|
| Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors | Journal of chromatography. B | | | 2007 | 555 | 1 |
|
| Synthesis, in vitro and in silico assessment of organometallic Rhenium(I) and Technetium(I) thymidine complexes | Journal of organometallic chemistry | | | 2007 | 628 | 0 |
|
| Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | Biochemical journal | | | 2006 | 509 | 0 |
|
| Inhibition of RET tyrosine kinase by SU5416 | Journal of molecular endocrinology | | | 2006 | 133 | 0 |
|
| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis | Nature cell biology | | | 2006 | 98 | 0 |
|
| Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling | Journal of medicinal chemistry | | | 2006 | 143 | 0 |
|
| Inhibition of Plasmodium falciparum Fatty Acid Biosynthesis: Evaluation of FabG, FabZ, and FabI as Drug Targets for Flavonoids | Journal of medicinal chemistry | | | 2006 | 203 | 1 |
|
| Tyrosine kinase drug discovery: what can be learned from solved crystal structures? | ARKIVOC | | | 2006 | 570 | 489 |
|
| In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells | Cancer research | | | 2006 | 535 | 1 |
|
| High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics | Protein expression and purification | | | 2006 | 77 | 0 |
|
| Recombinant expression and biochemical characterization of the unique elongating β-Ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates | The Journal of biological chemistry | | | 2006 | 176 | 147 |
|
| Abl inhibitor BMS354825 binding mode in Abelson kinase revealed by molecular docking studies | Leukemia | | | 2005 | 133 | 0 |
|
| An enzyme-linked immunosorbent assay to screen for inhibitors of the oncogenic anaplastic lymphoma kinase | Haematologica | | | 2005 | 445 | 220 |
|
| The crystal structure of PfFabZ, the unique β‐hydroxyacyl‐ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum | Protein science | | | 2005 | 87 | 240 |
|
| Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity | Biochemistry | | | 2005 | 570 | 0 |
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