LS
Scapozza, Leonardo
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model | Pharmaceutics |  | 2024 | 112 | 87 | ||
| Compound K14 inhibits bacterial killing and protease activity in Dictyostelium discoideum phagosomes | PloS one | | 2024 | 40 | 22 | ||
| Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog pathway inhibitor-1 | Nature communications | | 2023 | 93 | 87 | ||
| Targeted Nanofitin-drug Conjugates Achieve Efficient Tumor Delivery and Therapeutic Effect in an EGFRpos Mouse Xenograft Model | Molecular cancer therapeutics | | 2023 | 66 | 20 | ||
| Challenges and Opportunities in the Oral Delivery of Recombinant Biologics | Pharmaceutics | | 2023 | 41 | 23 | ||
| CEMIP ( HYBID , KIAA1199 ): structure, function and expression in health and disease | The FEBS journal | | 2022 | 182 | 199 | ||
| Discovery of anti-Formin-like 1 protein (FMNL1) antibodies in membranous nephropathy and other glomerular diseases | Scientific reports | | 2022 | 279 | 108 | ||
| 5-ethyl-2’-deoxyuridine fragilizes Klebsiella pneumoniae outer wall and facilitates intracellular killing by phagocytic cells | PloS one | | 2022 | 78 | 71 | ||
| Chemoenzymatic synthesis of original stilbene dimers possessing wnt inhibition activity in triple-negative breast cancer cells using the enzymatic secretome of Botrytis cinerea pers | Frontiers in chemistry | | 2022 | 231 | 118 | ||
| Functional and anatomical characterization of atrophic age-related macular degeneration in an aged mouse model | Journal of Ophthalmology and Research | | 2021 | 449 | 290 | ||
| Glomerular macrophages in human auto- and allo-immune nephritis | Cells | | 2021 | 241 | 138 | ||
| Heat-stability study of various insulin types in tropical temperature conditions: new insights towards improving diabetes care | PLOS ONE | | 2021 | 388 | 276 | ||
| Novel Mechanism for an Old Drug: Phenazopyridine is a Kinase Inhibitor Affecting Autophagy and Cellular Differentiation | Frontiers in pharmacology | | 2021 | 145 | 72 | ||
| From Conception to Development: Investigating PROTACs Features for Improved Cell Permeability and Successful Protein Degradation | Frontiers in Chemistry | | 2021 | 492 | 628 | ||
| Platelet Transforming Growth Factor-β1 Induces Liver Sinusoidal Endothelial Cells to Secrete Interleukin-6 | Cells | | 2020 | 355 | 166 | ||
| Identification of anti-mycobacterium and anti-legionella compounds with potential distinctive structural scaffolds from an HD-PBL using phenotypic screens in amoebae host models | Frontiers in Microbiology | | 2020 | 323 | 189 | ||
| Cooperative binding of the tandem WW domains of PLEKHA7 to PDZD11 promotes conformation-dependent interaction with tetraspanin 33 | Journal of Biological Chemistry | | 2020 | 292 | 148 | ||
| Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer | Biochimica et Biophysica Acta. Reviews on Cancer | | 2019 | 486 | 619 | ||
| DDR1 role in fibrosis and its pharmacological targeting | Biochimica et Biophysica Acta - Molecular Cell Research |  | 2019 | 426 | 3 | ||
| Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models | | 2018 | 641 | 340 | |||
| Autoregulation of Class II Alpha PI3K Activity by Its Lipid-Binding PX-C2 Domain Module | Molecular Cell | | 2018 | 470 | 0 | ||
| Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets | Scientific Reports | | 2018 | 557 | 204 | ||
| Tamoxifen prolongs survival and alleviates symptoms in mice with fatal X-linked myotubular myopathy | Nature Communications | | 2018 | 506 | 257 | ||
| Modeling and resistant alleles explain the selectivity of antimalarial compound 49c towards apicomplexan aspartyl proteases | EMBO Journal | | 2018 | 678 | 15 | ||
| Inhibitors of Mycobacterium marinum virulence identified in a Dictyostelium discoideum host model | PLOS ONE | | 2017 | 490 | 232 | ||
| Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks | Molecular cell | | 2016 | 61 | 127 | ||
| In silico driven design and synthesis of rhodanine derivatives as novel antibacterials targeting the enoyl reductase InhA | Journal of medicinal chemistry | | 2016 | 669 | 6 | ||
| A subset of N-substituted phenothiazines inhibits NADPH oxidases | Free radical biology & medicine | | 2015 | 592 | 597 | ||
| A novel biocompatible hyaluronic acid-chitosan hybrid hydrogel for osteoarthrosis therapy | International journal of pharmaceutics | | 2015 | 901 | 2 | ||
| Amoebae-Based Screening Reveals a Novel Family of Compounds Restricting Intracellular Legionella pneumophila | ACS infectious diseases | | 2015 | 684 | 488 | ||
| Adrenergic antagonists restrict replication of Legionella | Microbiology | | 2015 | 614 | 0 | ||
| Differences in Conformational Dynamics between Plasmodium falciparum and Human Hsp90 Orthologues Enable the Structure-Based Discovery of Pathogen-Selective Inhibitors | Journal of medicinal chemistry | | 2014 | 710 | 659 | ||
| Establishment and validation of whole-cell based fluorescence assays to identify anti-mycobacterial compounds using the Acanthamoeba castellanii-Mycobacterium marinum host-pathogen system | PloS one | | 2014 | 758 | 326 | ||
| Diapocynin, a Dimer of the NADPH Oxidase Inhibitor Apocynin, Reduces ROS Production and Prevents Force Loss in Eccentrically Contracting Dystrophic Muscle | PloS one | | 2014 | 626 | 607 | ||
| Synthesis and in vitro evaluation of a novel radioligand for αvβ3 integrin receptor imaging: [18F]FPPA-c(RGDfK) | Bioorganic & medicinal chemistry letters | | 2013 | 687 | 0 | ||
| The pharmaceutical biochemistry group: where pharmaceutical chemistry meets biology and drug delivery | Chimia | | 2012 | 834 | 721 | ||
| NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action | British journal of pharmacology | | 2011 | 743 | 0 | ||
| Noninvasive transdermal iontophoretic delivery of biologically active human basic fibroblast growth factor | Molecular pharmaceutics | | 2011 | 615 | 2 | ||
| Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | Antioxidants & redox signaling | | 2009 | 670 | 2 | ||
| Development and validation of a capillary electrophoresis method for the characterization of herpes simplex virus type 1 (HSV-1) thymidine kinase substrates and inhibitors | Journal of chromatography. B | | 2007 | 533 | 0 | ||
| Synthesis, in vitro and in silico assessment of organometallic Rhenium(I) and Technetium(I) thymidine complexes | Journal of organometallic chemistry | | 2007 | 611 | 0 | ||
| Analysis of the cross-reactivity and of the 1.5 A crystal structure of the Malassezia sympodialis Mala s 6 allergen, a member of the cyclophilin pan-allergen family | Biochemical journal | | 2006 | 491 | 0 | ||
| Inhibition of RET tyrosine kinase by SU5416 | Journal of Molecular Endocrinology | | 2006 | 120 | 0 | ||
| Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis | Nature cell biology | | 2006 | 79 | 0 | ||
| Structural Insights into the ATP Binding Pocket of the Anaplastic Lymphoma Kinase by Site-Directed Mutagenesis, Inhibitor Binding Analysis, and Homology Modeling | Journal of medicinal chemistry | | 2006 | 129 | 0 | ||
| Inhibition of Plasmodium falciparum Fatty Acid Biosynthesis: Evaluation of FabG, FabZ, and FabI as Drug Targets for Flavonoids | Journal of medicinal chemistry | | 2006 | 188 | 1 | ||
| Tyrosine kinase drug discovery: what can be learned from solved crystal structures? | ARKIVOC | | 2006 | 550 | 406 | ||
| In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells | Cancer research | | 2006 | 518 | 1 | ||
| High-level expression and purification of human thymidine kinase 1: Quaternary structure, stability, and kinetics | Protein expression and purification | | 2006 | 66 | 0 | ||
| Recombinant expression and biochemical characterization of the unique elongating β-Ketoacyl-acyl carrier protein synthase involved in fatty acid biosynthesis of Plasmodium falciparum using natural and artificial substrates | The Journal of biological chemistry | | 2006 | 161 | 78 | ||
| Abl inhibitor BMS354825 binding mode in Abelson kinase revealed by molecular docking studies | Leukemia | | 2005 | 118 | 0 | ||
| An enzyme-linked immunosorbent assay to screen for inhibitors of the oncogenic anaplastic lymphoma kinase | Haematologica | | 2005 | 430 | 154 | ||
| The crystal structure of PfFabZ, the unique β‐hydroxyacyl‐ACP dehydratase involved in fatty acid biosynthesis of Plasmodium falciparum | Protein science | | 2005 | 74 | 74 | ||
| Unique substrate specificity of anaplastic lymphoma kinase (ALK): development of phosphoacceptor peptides for the assay of ALK activity | Biochemistry | | 2005 | 556 | 0 |
