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Title

Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe

Authors
Bonnin, R A
Poirel, L
Naas, T
Pirs, M
Published in Clinical Microbiology and Infection. 2012, vol. 18, no. 9, p. E362-5
Abstract Multidrug-resistant and New Delhi metallo-β-lactamase 1 (NDM-1) -producing Acinetobacter baumannii are increasingly reported. A collection of five NDM-1-positive A. baumannii isolates recovered in four European countries were analysed. Genotyping was performed by pulsed-field gel electrophoresis, multiplex PCR sequence typing, Diversilab and multilocus sequence typing. Three distinct sequence types were identified. All isolates harboured a chromosomally located bla(NDM-1) gene within a Tn125-like transposon. One isolate co-expressed another unrelated carbapenemase OXA-23. This report constitutes the first epidemiological study of NDM-1-producing A. baumannii from four countries.
Keywords Acinetobacter Infections/microbiologyAcinetobacter baumannii/classification/drug effects/enzymology/geneticsAnti-Bacterial Agents/pharmacologyDNA Transposable Elements/geneticsEuropeHumansMicrobial Sensitivity TestsBeta-Lactam ResistanceBeta-Lactamases/biosynthesis/genetics
Identifiers
PMID: 22738206
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Article (Published version) (192 Kb) - public document Free access
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Research group Analyse génomique et fonctionnelle du staphylocoque doré (604)
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BONNIN, R A et al. Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe. In: Clinical Microbiology and Infection, 2012, vol. 18, n° 9, p. E362-5. https://archive-ouverte.unige.ch/unige:28378

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Deposited on : 2013-06-04

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