Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe

Article Article scientifique Article Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe eng 2012 author Bonnin R A author Poirel L author Naas T author Pirs M author Semeko Koffi 678651 author Schrenzel Jacques 29184 author Nordmann Pascal 67288 E362-365 10.1111/j.1469-0691.2012.03928.x 22738206 1198-743X Multidrug-resistant and New Delhi metallo-β-lactamase 1 (NDM-1) -producing Acinetobacter baumannii are increasingly reported. A collection of five NDM-1-positive A. baumannii isolates recovered in four European countries were analysed. Genotyping was performed by pulsed-field gel electrophoresis, multiplex PCR sequence typing, Diversilab and multilocus sequence typing. Three distinct sequence types were identified. All isolates harboured a chromosomally located bla(NDM-1) gene within a Tn125-like transposon. One isolate co-expressed another unrelated carbapenemase OXA-23. This report constitutes the first epidemiological study of NDM-1-producing A. baumannii from four countries. Acinetobacter Infections/microbiology Acinetobacter baumannii/classification/drug effects/enzymology/genetics Anti-Bacterial Agents/pharmacology DNA Transposable Elements/genetics Europe Humans Microbial Sensitivity Tests Beta-Lactam Resistance Beta-Lactamases/biosynthesis/genetics Dewey 616 56 Département de médecine 221 false 338 Génomique et microbiote 604 Clinical microbiology and infection 18 9 c67412ae-51e2-48c6-83ae-ea6aa79dac64 Article (Published version) Public j.1469-0691.2012.03928.x.pdf 197017 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de médecine

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Dissemination of New Delhi metallo-β-lactamase-1-producing Acinetobacter baumannii in Europe	Clinical microbiology and infection			2012	641	399

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Semeko, Koffi