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Title

Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study

Authors
Lee, Andie S.
Published in Clinical infectious diseases. 2011, vol. 52, no. 12, p. 1422-30
Abstract The clinical importance of low-level mupirocin resistance and genotypic chlorhexidine resistance remains unclear. We aimed to determine whether resistance to these agents increases the risk of persistent methicillin-resistant Staphylococcus aureus (MRSA) carriage after their use for topical decolonization therapy.
Keywords Administration, TopicalAgedAged, 80 and overAnti-Infective Agents, Local/administration & dosage/pharmacologyCarrier State/drug therapy/microbiologyCase-Control StudiesChlorhexidine/administration & dosage/pharmacologyDNA, Bacterial/geneticsDrug Resistance, BacterialFemaleGenes, BacterialGenotypeHumansMaleMethicillin-Resistant Staphylococcus aureus/drug effects/isolation & purificationMiddle AgedMupirocin/administration & dosage/pharmacologyPolymerase Chain Reaction/methodsStaphylococcal Infections/drug therapy/microbiologyTreatment Outcome
Identifiers
PMID: 21628482
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Structures
Research groups Analyse génomique et fonctionnelle du staphylocoque doré (604)
Epidémiologie et contrôle de la résistance aux antibiotiques (866)
Staphylocoques dorés résistants à la méthicilline et hygiène hospitalière (330)
Citation
(ISO format)
LEE, Andie S. et al. Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study. In: Clinical infectious diseases, 2011, vol. 52, n° 12, p. 1422-30. doi: 10.1093/cid/cir233 https://archive-ouverte.unige.ch/unige:25014

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Deposited on : 2013-01-04

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