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Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study

Publié dansClinical infectious diseases, vol. 52, no. 12, p. 1422-1430
Date de publication2011
Résumé

The clinical importance of low-level mupirocin resistance and genotypic chlorhexidine resistance remains unclear. We aimed to determine whether resistance to these agents increases the risk of persistent methicillin-resistant Staphylococcus aureus (MRSA) carriage after their use for topical decolonization therapy.

Mots-clés
  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Anti-Infective Agents, Local/administration & dosage/pharmacology
  • Carrier State/drug therapy/microbiology
  • Case-Control Studies
  • Chlorhexidine/administration & dosage/pharmacology
  • DNA, Bacterial/genetics
  • Drug Resistance, Bacterial
  • Female
  • Genes, Bacterial
  • Genotype
  • Humans
  • Male
  • Methicillin-Resistant Staphylococcus aureus/drug effects/isolation & purification
  • Middle Aged
  • Mupirocin/administration & dosage/pharmacology
  • Polymerase Chain Reaction/methods
  • Staphylococcal Infections/drug therapy/microbiology
  • Treatment Outcome
Citation (format ISO)
LEE, Andie S. et al. Impact of combined low-level mupirocin and genotypic chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study. In: Clinical infectious diseases, 2011, vol. 52, n° 12, p. 1422–1430. doi: 10.1093/cid/cir233
Fichiers principaux (1)
Article (Published version)
accessLevelRestricted
Identifiants
ISSN du journal1058-4838
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Informations techniques

Création26.10.2012 15:54:00
Première validation26.10.2012 15:54:00
Heure de mise à jour14.03.2023 19:53:33
Changement de statut14.03.2023 19:53:33
Dernière indexation16.01.2024 00:46:10
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