Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice
Published inDiabetes, vol. 60, no. 11, p. 2872-2882
Publication date2011
Abstract
Keywords
- Animals
- Apoptosis/drug effects
- Cell Count
- Diabetes Mellitus, Experimental/blood/chemically induced/metabolism/pathology
- Diphtheria Toxin/toxicity
- Glucagon/blood/genetics/metabolism
- Glucagon-Secreting Cells/drug effects/metabolism/pathology/secretion
- Hyperglycemia/chemically induced/prevention & control
- Hypoglycemia/prevention & control
- Insulin/blood/metabolism
- Insulin-Secreting Cells/drug effects/metabolism/pathology/secretion
- Intercellular Signaling Peptides and Proteins/genetics/metabolism
- Male
- Mice
- Mice, Transgenic
- Pancreas/drug effects/metabolism/pathology
- Promoter Regions, Genetic
- Receptors, Glucagon/metabolism
- Selective Estrogen Receptor Modulators/pharmacology
- Signal Transduction
- Streptozocin/toxicity
- Tamoxifen/pharmacology
Citation (ISO format)
THOREL, Fabrizio et al. Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice. In: Diabetes, 2011, vol. 60, n° 11, p. 2872–2882. doi: 10.2337/db11-0876
Main files (1)
Article (Published version)
Identifiers
- PID : unige:24821
- DOI : 10.2337/db11-0876
- PMID : 21926270
ISSN of the journal0012-1797