CW
| Title | Published in | Access level | OA Policy | Year | Views | Downloads | |
|---|---|---|---|---|---|---|---|
| Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells | Cell Metabolism |  | 2019 | 473 | 242 | ||
| Silencing of the FTO gene inhibits insulin secretion: an in vitro study using GRINCH cells | Molecular and Cellular Endocrinology |  | 2018 | 299 | 1 | ||
| Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes | Diabetologia | | 2018 | 368 | 109 | ||
| Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production | Molecular and Cellular Endocrinology | | 2018 | 412 | 0 | ||
| Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase | Diabetes | | 2018 | 365 | 0 | ||
| Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes | Nature Communications | | 2017 | 379 | 199 | ||
| Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell | Scientific Reports | | 2017 | 384 | 138 | ||
| Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes | Science Translational Medicine | | 2017 | 433 | 0 | ||
| Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state? | The International Journal of Biochemistry & Cell Biology | | 2017 | 1 684 | 898 | ||
| Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes | Experimental and Molecular Medicine | | 2017 | 414 | 378 | ||
| Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes | Molecular and cellular endocrinology | | 2017 | 546 | 477 | ||
| Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high phosphate-induced mitochondrial oxidative stress and defective insulin secretion | The FASEB journal | | 2016 | 475 | 479 | ||
| Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes | Diabetologia | | 2016 | 448 | 200 | ||
| Microbial signals to the brain control weight | Nature | | 2016 | 499 | 307 | ||
| Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells | American journal of physiology: endocrinology and metabolism | | 2015 | 538 | 0 | ||
| Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs? | Nature medicine | | 2015 | 560 | 0 | ||
| Inhibition of the malate–aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion | Biochemical journal | | 2015 | 508 | 398 | ||
| Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing Cells | The Journal of biological chemistry | | 2015 | 601 | 219 | ||
| Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia | Human molecular genetics | | 2015 | 563 | 579 | ||
| Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism | Proceedings of the National Academy of Sciences of the United States of America | | 2014 | 623 | 487 | ||
| TCF7L2 is a master regulator of insulin production and processing | Human molecular genetics | | 2014 | 702 | 501 | ||
| Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion | PLOS genetics | | 2014 | 655 | 276 | ||
| Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction | Molecular and cellular endocrinology | | 2013 | 605 | 0 | ||
| DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets | BMC medical genetics | | 2013 | 601 | 485 | ||
| Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release | Biochemical journal | | 2013 | 576 | 0 | ||
| Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells | Molecular and cellular endocrinology | | 2013 | 568 | 0 | ||
| Mitochondrial signals drive insulin secretion in the pancreatic β-cell | Molecular and cellular endocrinology | | 2012 | 534 | 0 | ||
| Improved characterization of the insulin secretory granule proteomes | Journal of proteomics |  | 2012 | 516 | 0 | ||
| A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets | Diabetologia | | 2012 | 586 | 449 | ||
| Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes | Molecular endocrinology | | 2012 | 578 | 747 | ||
| A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets | Cell metabolism | | 2012 | 577 | 423 | ||
| Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells | Journal of lipid research | | 2012 | 673 | 484 | ||
| Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-secretion coupling in INS-1E clonal β-cells | Biochimica et biophysica acta | | 2012 | 553 | 854 | ||
| Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes | Cell metabolism | | 2012 | 625 | 619 | ||
| Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box | Molecular and cellular endocrinology | | 2012 | 579 | 1 404 | ||
| Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells | Korean Journal of Physiology and Pharmacology | | 2012 | 601 | 339 | ||
| Modulation of neuronal pentraxin 1 expression in rat pancreatic β-cells submitted to chronic glucotoxic stress | Molecular & cellular proteomics | | 2012 | 591 | 0 | ||
| Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets | Diabetologia | | 2011 | 587 | 252 | ||
| In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice | Diabetes | | 2011 | 642 | 1 571 | ||
| Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | The Journal of biological chemistry | | 2011 | 561 | 0 | ||
| Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells | Molecular and cellular endocrinology | | 2011 | 648 | 0 | ||
| Mitochondrial matrix calcium is an activating signal for hormone secretion | Cell metabolism | | 2011 | 502 | 0 | ||
| The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | | 2011 | 673 | 0 | ||
| Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Diabetes, obesity & metabolism | | 2011 | 597 | 0 | ||
| Imeglimin - A New Oral Anti-Diabetic that Targets the Three Key Defects of type 2 Diabetes | Journal of diabetes & metabolism | | 2011 | 862 | 1 | ||
| Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation | The Journal of biological chemistry | | 2011 | 599 | 315 | ||
| Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice | Diabetes | | 2011 | 614 | 341 | ||
| Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors | PloS one | | 2010 | 748 | 286 | ||
| INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells | Diabetes | | 2010 | 561 | 313 | ||
| Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells | The FASEB journal | | 2010 | 666 | 534 | ||
| Evidence against a direct role of klotho in insulin resistance | Pflügers Archiv | | 2010 | 639 | 346 | ||
| Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation | Biochimica et biophysica acta | | 2010 | 580 | 2 | ||
| AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF | The Journal of biological chemistry | | 2010 | 441 | 276 | ||
| Early activation of the fatty acid metabolism pathway by chronic high glucose exposure in rat insulin secretory beta-cells | Proteomics | | 2010 | 555 | 0 | ||
| Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells | British journal of pharmacology | | 2009 | 575 | 0 | ||
| Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation | EMBO journal | | 2009 | 515 | 0 | ||
| Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets | The Journal of biological chemistry | | 2009 | 557 | 0 | ||
| PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression | Cell metabolism | | 2009 | 545 | 0 | ||
| Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells | The Journal of biological chemistry | | 2009 | 449 | 536 | ||
| Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | International journal of biochemistry & cell biology | | 2009 | 638 | 0 | ||
| Linking fatty acid stress to beta-cell mitochondrial dynamics | Diabetes | | 2009 | 424 | 0 | ||
| Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell | Cell calcium | | 2008 | 509 | 0 | ||
| TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis | Journal of Endocrinology | | 2008 | 538 | 0 | ||
| Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis | The FASEB journal | | 2008 | 531 | 0 | ||
| Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets | Experimental and clinical endocrinology & diabetes | 2008 | 491 | 0 | |||
| The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells | Molecular and cellular biology | | 2008 | 456 | 0 | ||
| Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells | The Journal of biological chemistry | | 2008 | 601 | 0 | ||
| Synaptotagmins bind calcium to release insulin | American journal of physiology: endocrinology and metabolism | | 2008 | 553 | 0 | ||
| Dual effect of cell-cell contact disruption on cytosolic calcium and insulin secretion | Endocrinology | | 2008 | 586 | 0 | ||
| Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy | The Journal of biological chemistry | | 2007 | 712 | 348 | ||
| Proteomics analysis of insulin secretory granules | Molecular & cellular proteomics | | 2007 | 630 | 606 | ||
| The Fas pathway is involved in pancreatic beta cell secretory function | Proceedings of the National Academy of Sciences of the United States of America | | 2007 | 591 | 0 | ||
| Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets | Genes and immunity | | 2007 | 567 | 0 | ||
| The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells | Oncogene | | 2007 | 578 | 0 | ||
| Mitochondrial GTP regulates glucose-stimulated insulin secretion | Cell metabolism | | 2007 | 573 | 458 | ||
| Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains | Endocrine reviews | | 2007 | 557 | 0 | ||
| Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species | Diabetologia | | 2007 | 579 | 142 | ||
| Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins | Experimental cell research | | 2006 | 602 | 458 | ||
| Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets | Diabetes | | 2006 | 664 | 844 | ||
| MicroRNAs: 'ribo-regulators' of glucose homeostasis | Nature medicine | | 2006 | 497 | 950 | ||
| Micro-ARN: ribo-régulateurs de l'homéostasie du glucose | MS. Médecine sciences | | 2006 | 556 | 231 | ||
| Minireview: implication of mitochondria in insulin secretion and action | Endocrinology | | 2006 | 545 | 262 | ||
| SV2A and SV2C are not vesicular Ca2+ transporters but control glucose-evoked granule recruitment | Journal of cell science | | 2005 | 508 | 331 | ||
| Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets | FEBS letters | | 2005 | 543 | 358 | ||
| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | | 2005 | 587 | 147 | ||
| Does chasing selected 'Fox' to the nucleus prevent diabetes? | Trends in molecular medicine | | 2005 | 573 | 352 | ||
| The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation | Cell metabolism | | 2005 | 513 | 593 | ||
| The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets | The Journal of cell biology | | 2004 | 530 | 623 | ||
| Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells | Endocrinology | | 2004 | 421 | 0 | ||
| GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule | The Journal of general physiology | | 2004 | 463 | 216 | ||
| Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues | Diabetes | | 2004 | 504 | 292 | ||
| Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity | Diabetologia | | 2004 | 546 | 167 | ||
| Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells | Nature cell biology | | 2003 | 531 | 0 | ||
| Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice | EMBO journal | | 2003 | 528 | 237 | ||
| Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death | The Journal of biological chemistry | | 2002 | 520 | 312 | ||
| Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release | The Journal of biological chemistry | | 2002 | 496 | 197 | ||
| Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues | The Journal of biological chemistry | | 2002 | 559 | 314 | ||
| Mitochondria respond to Ca2+ already in the submicromolar range: correlation with redox state | Cell calcium | | 2002 | 549 | 476 | ||
| Beta-cell mitochondria and insulin secretion: messenger role of nucleotides and metabolites | Diabetes | | 2002 | 463 | 204 | ||
| Experimental models of transcription factor-associated maturity-onset diabetes of the young | Diabetes | | 2002 | 594 | 0 | ||
| Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation | The Journal of biological chemistry | | 2001 | 597 | 1 597 | ||
| Expression and localisation of synaptotagmin isoforms in endocrine beta-cells: their function in insulin exocytosis | Journal of cell science | | 2001 | 490 | 144 | ||
| Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma) | Arthritis research & therapy | | 2001 | 427 | 128 | ||
| Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix | Diabetes | | 2001 | 550 | 0 | ||
| GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells | The Journal of biological chemistry | | 2001 | 504 | 223 | ||
| Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice | Endocrinology | | 2001 | 534 | 0 | ||
| Mitochondrial calcium oscillations in C2C12 myotubes | The Journal of biological chemistry | | 2001 | 522 | 0 | ||
| Mitochondrial function in normal and diabetic beta-cells | Nature | | 2001 | 518 | 686 | ||
| A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion | Diabetes | | 2001 | 536 | 0 | ||
| Vasopressin-induced von Willebrand factor secretion from endothelial cells involves V2 receptors and cAMP | The Journal of clinical investigation | | 2000 | 560 | 540 | ||
| Modulation of glutamate generation in mitochondria affects hormone secretion in INS-1E beta cells | IUBMB life | | 2000 | 532 | 237 | ||
| What couples glycolysis to mitochondrial signal generation in glucose-stimulated insulin secretion? | IUBMB life | | 2000 | 527 | 0 | ||
| Hepatocyte nuclear factor 4alpha regulates the expression of pancreatic beta -cell genes implicated in glucose metabolism and nutrient-induced insulin secretion | The Journal of biological chemistry | | 2000 | 573 | 218 | ||
| Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance | The Journal of clinical investigation | | 2000 | 494 | 0 | ||
| The Rab3-interacting molecule RIM is expressed in pancreatic beta-cells and is implicated in insulin exocytosis | FEBS letters | | 2000 | 537 | 364 | ||
| Beta-cell mitochondria in the regulation of insulin secretion: a new culprit in type II diabetes | Diabetologia | | 2000 | 484 | 0 | ||
| Mitochondrial signals in glucose-stimulated insulin secretion in the beta cell | Journal of physiology | | 2000 | 492 | 303 | ||
| Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells | The Journal of biological chemistry | | 1999 | 551 | 332 | ||
| Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells | The Journal of clinical investigation | | 1999 | 566 | 227 | ||
| Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis | Nature | | 1999 | 587 | 468 | ||
| Reactive oxygen metabolites increase mitochondrial calcium in endothelial cells: implication of the Ca2+/Na+ exchanger | Journal of cell science | | 1999 | 516 | 194 | ||
| Expression of alpha-1 proteinase inhibitor in human islet microvascular endothelial cells | Diabetes | | 1999 | 709 | 0 | ||
| Subcellular distribution and function of Rab3A, B, C, and D isoforms in insulin-secreting cells | Molecular endocrinology | | 1999 | 521 | 501 | ||
| Role of mitochondria in metabolism-secretion coupling of insulin release in the pancreatic beta-cell | BioFactors | | 1998 | 472 | 266 | ||
| Ca2+-independent insulin exocytosis induced by alpha-latrotoxin requires latrophilin, a G protein-coupled receptor | EMBO journal | | 1998 | 614 | 280 | ||
| Role of mitochondrial calcium in metabolism-secretion coupling in nutrient-stimulated insulin release | Diabetes & metabolism | | 1998 | 534 | 237 | ||
| GH signalling in pancreatic beta-cells | Endocrine journal | | 1998 | 461 | 245 | ||
| Dominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line | EMBO journal | | 1998 | 533 | 283 | ||
| Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells | FEBS letters | | 1998 | 546 | 612 | ||
| Desensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell | The Journal of biological chemistry | | 1998 | 569 | 216 | ||
| Cysteine-string proteins regulate exocytosis of insulin independent from transmembrane ion fluxes | FEBS letters | | 1998 | 539 | 0 | ||
| Acute von Willebrand factor secretion from the endothelium in vivo: assessment through plasma propeptide (vWf:AgII) Levels | Thrombosis and haemostasis | | 1997 | 643 | 579 | ||
| Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cells | The Journal of clinical investigation | | 1996 | 544 | 329 | ||
| Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells | Cell calcium | | 1996 | 585 | 333 | ||
| Mutational analysis of VAMP domains implicated in Ca2+-induced insulin exocytosis | EMBO journal | | 1996 | 489 | 0 | ||
| SNAP-25 is expressed in islets of Langerhans and is involved in insulin release | The Journal of cell biology | | 1995 | 521 | 0 | ||
| Intracellular pattern of cytosolic Ca2+ changes during adhesion and multiple phagocytosis in human neutrophils. Dynamics of intracellular Ca2+ stores | Blood | | 1995 | 509 | 0 | ||
| Calcium signalling: comparison of the role of Ca2+ influx in excitable endocrine and non-excitable myeloid cells | Advances in second messenger and phosphoprotein research | 1993 | 500 | 0 |