| Harnessing distinct tissue-resident immune niches via S100A9/TLR4 improves ketone, lipid, and glucose metabolism | Endocrinology | | | 2025 | 76 | 622 |
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| Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells | Cell Metabolism | | | 2019 | 569 | 442 |
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| Silencing of the FTO gene inhibits insulin secretion: an in vitro study using GRINCH cells | Molecular and Cellular Endocrinology | | | 2018 | 361 | 1 |
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| Systems biology of the IMIDIA biobank from organ donors and pancreatectomised patients defines a novel transcriptomic signature of islets from individuals with type 2 diabetes | Diabetologia | | | 2018 | 455 | 142 |
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| Sulforaphane improves disrupted ER-mitochondria interactions and suppresses exaggerated hepatic glucose production | Molecular and Cellular Endocrinology | | | 2018 | 491 | 0 |
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| Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase | Diabetes | | | 2018 | 440 | 0 |
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| Sox5 regulates beta-cell phenotype and is reduced in type 2 diabetes | Nature Communications | | | 2017 | 457 | 250 |
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| Elevated miR-130a/miR130b/miR-152 expression reduces intracellular ATP levels in the pancreatic beta cell | Scientific Reports | | | 2017 | 453 | 267 |
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| Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes | Science Translational Medicine | | | 2017 | 538 | 0 |
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| Epigallocatechin-3-gallate (EGCG) activates AMPK through the inhibition of glutamate dehydrogenase in muscle and pancreatic ß-cells: A potential beneficial effect in the pre-diabetic state? | The International Journal of Biochemistry & Cell Biology | | | 2017 | 1,908 | 1,632 |
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| Oxidative stress and calcium dysregulation by palmitate in type 2 diabetes | Experimental and Molecular Medicine | | | 2017 | 488 | 1,310 |
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| Endogenous beta-cell CART regulates insulin secretion and transcription of beta-cell genes | Molecular and cellular endocrinology | | | 2017 | 633 | 792 |
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| Intracellular alkalinization by phosphate uptake via type III sodium-phosphate cotransporter participates in high phosphate-induced mitochondrial oxidative stress and defective insulin secretion | The FASEB journal | | | 2016 | 590 | 675 |
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| Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes | Diabetologia | | | 2016 | 567 | 367 |
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| Microbial signals to the brain control weight | Nature | | | 2016 | 580 | 473 |
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| Mitochondrial oxidative stress mediates high-phosphate-induced secretory defects and apoptosis in insulin-secreting cells | American journal of physiology: endocrinology and metabolism | | | 2015 | 616 | 0 |
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| Beta cell glutamate receptor antagonists: novel oral antidiabetic drugs? | Nature medicine | | | 2015 | 631 | 0 |
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| Inhibition of the malate–aspartate shuttle in mouse pancreatic islets abolishes glucagon secretion without affecting insulin secretion | Biochemical journal | | | 2015 | 604 | 712 |
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| Essential Role of Mitochondrial Ca2+ Uniporter in the Generation of Mitochondrial pH Gradient and Metabolism-Secretion Coupling in Insulin-releasing Cells | The Journal of biological chemistry | | | 2015 | 657 | 305 |
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| Identification of novel genes for glucose metabolism based upon expression pattern in human islets and effect on insulin secretion and glycemia | Human molecular genetics | | | 2015 | 649 | 970 |
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| Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolism | Proceedings of the National Academy of Sciences of the United States of America | | | 2014 | 705 | 1,526 |
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| TCF7L2 is a master regulator of insulin production and processing | Human molecular genetics | | | 2014 | 768 | 935 |
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| Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion | PLOS genetics | | | 2014 | 746 | 448 |
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| Microarray analysis of isolated human islet transcriptome in type 2 diabetes and the role of the ubiquitin-proteasome system in pancreatic beta cell dysfunction | Molecular and cellular endocrinology | | | 2013 | 709 | 0 |
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| DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets | BMC medical genetics | | | 2013 | 701 | 602 |
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| Time-resolved metabolomics analysis of β-cells implicates the pentose phosphate pathway in the control of insulin release | Biochemical journal | | | 2013 | 687 | 0 |
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| Mitochondrial phosphate transport during nutrient stimulation of INS-1E insulinoma cells | Molecular and cellular endocrinology | | | 2013 | 662 | 0 |
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| Mitochondrial signals drive insulin secretion in the pancreatic β-cell | Molecular and cellular endocrinology | | | 2012 | 585 | 0 |
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| Improved characterization of the insulin secretory granule proteomes | Journal of proteomics | | | 2012 | 601 | 0 |
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| A local glucagon-like peptide 1 (GLP-1) system in human pancreatic islets | Diabetologia | | | 2012 | 669 | 723 |
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| Increased DNA methylation and decreased expression of PDX-1 in pancreatic islets from patients with type 2 diabetes | Molecular endocrinology | | | 2012 | 675 | 1,001 |
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| A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets | Cell metabolism | | | 2012 | 642 | 1,247 |
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| Activation of the unfolded protein response pathway causes ceramide accumulation in yeast and INS-1E insulinoma cells | Journal of lipid research | | | 2012 | 731 | 556 |
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| Pyruvate dehydrogenase E1α phosphorylation is induced by glucose but does not control metabolism-secretion coupling in INS-1E clonal β-cells | Biochimica et biophysica acta | | | 2012 | 622 | 981 |
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| Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes | Cell metabolism | | | 2012 | 702 | 799 |
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| Human Krüppel-like factor 11 differentially regulates human insulin promoter activity in β-cells and non-β-cells via p300 and PDX1 through the regulatory sites A3 and CACCC box | Molecular and cellular endocrinology | | | 2012 | 676 | 1,736 |
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| Defective Mitochondrial Function and Motility Due to Mitofusin 1 Overexpression in Insulin Secreting Cells | Korean Journal of Physiology and Pharmacology | | | 2012 | 678 | 376 |
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| Modulation of neuronal pentraxin 1 expression in rat pancreatic β-cells submitted to chronic glucotoxic stress | Molecular & cellular proteomics | | | 2012 | 652 | 0 |
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| Insulin promoter DNA methylation correlates negatively with insulin gene expression and positively with HbA(1c) levels in human pancreatic islets | Diabetologia | | | 2011 | 686 | 325 |
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| In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice | Diabetes | | | 2011 | 717 | 1,598 |
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| Hepatic nuclear factor 1alpha (HNF1alpha) dysfunction down-regulates X-box-binding protein 1 (XBP1) and sensitizes beta-cells to endoplasmic reticulum stress | The Journal of biological chemistry | | | 2011 | 639 | 0 |
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| Reduction of plasma membrane glutamate transport potentiates insulin but not glucagon secretion in pancreatic islet cells | Molecular and cellular endocrinology | | | 2011 | 739 | 0 |
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| Mitochondrial matrix calcium is an activating signal for hormone secretion | Cell metabolism | | | 2011 | 559 | 0 |
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| The liver receptor homolog-1 (LRH-1) is expressed in human islets and protects {beta}-cells against stress-induced apoptosis | Human molecular genetics | | | 2011 | 820 | 0 |
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| Taspoglutide, a novel human once-weekly GLP-1 analogue, protects pancreatic β-cells in vitro and preserves islet structure and function in the Zucker diabetic fatty rat in vivo | Diabetes, obesity & metabolism | | | 2011 | 685 | 0 |
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| Imeglimin - A New Oral Anti-Diabetic that Targets the Three Key Defects of type 2 Diabetes | Journal of diabetes & metabolism | | | 2011 | 1,002 | 1 |
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| Bone morphogenetic protein 3 controls insulin gene expression and is down-regulated in INS-1 cells inducibly expressing a hepatocyte nuclear factor 1A-maturity-onset diabetes of the young mutation | The Journal of biological chemistry | | | 2011 | 672 | 373 |
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| Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice | Diabetes | | | 2011 | 683 | 422 |
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| Type 2 diabetes susceptibility gene expression in normal or diabetic sorted human alpha and beta cells: correlations with age or BMI of islet donors | PloS one | | | 2010 | 905 | 393 |
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| INS-1 cells undergoing caspase-dependent apoptosis enhance the regenerative capacity of neighboring cells | Diabetes | | | 2010 | 637 | 378 |
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| Mitochondrial matrix pH controls oxidative phosphorylation and metabolism-secretion coupling in INS-1E clonal beta cells | The FASEB journal | | | 2010 | 793 | 807 |
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| Evidence against a direct role of klotho in insulin resistance | Pflügers Archiv | | | 2010 | 730 | 509 |
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| Facilitation of fatty acid uptake by CD36 in insulin-producing cells reduces fatty-acid-induced insulin secretion and glucose regulation of fatty acid oxidation | Biochimica et biophysica acta | | | 2010 | 655 | 2 |
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| AMP-activated protein kinase mediates apoptosis in response to bioenergetic stress through activation of the pro-apoptotic Bcl-2 homology domain-3-only protein BMF | The Journal of biological chemistry | | | 2010 | 537 | 398 |
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| Amiloride derivatives induce apoptosis by depleting ER Ca(2+) stores in vascular endothelial cells | British journal of pharmacology | | | 2009 | 670 | 0 |
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| Matrix alkalinization: a novel mitochondrial signal for sustained pancreatic beta-cell activation | EMBO journal | | | 2009 | 579 | 0 |
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| Mitochondrial dysfunction contributes to impaired insulin secretion in INS-1 cells with dominant-negative mutations of HNF-1alpha and in HNF-1alpha-deficient islets | The Journal of biological chemistry | | | 2009 | 638 | 0 |
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| PDX1 deficiency causes mitochondrial dysfunction and defective insulin secretion through TFAM suppression | Cell metabolism | | | 2009 | 631 | 0 |
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| Requirement for aralar and its Ca2+-binding sites in Ca2+ signal transduction in mitochondria from INS-1 clonal beta-cells | The Journal of biological chemistry | | | 2009 | 596 | 700 |
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| Dynamin-related protein 1 mediates high glucose induced pancreatic beta cell apoptosis | International journal of biochemistry & cell biology | | | 2009 | 761 | 0 |
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| Impact of mitochondrial calcium on the coupling of metabolism to insulin secretion in the pancreatic beta-cell | Cell calcium | | | 2008 | 588 | 0 |
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| TRIB3 [corrected] is implicated in glucotoxicity- and endoplasmic reticulum-stress-induced [corrected] beta-cell apoptosis | Journal of Endocrinology | | | 2008 | 655 | 0 |
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| Synaptotagmin VII splice variants alpha, beta, and delta are expressed in pancreatic beta-cells and regulate insulin exocytosis | The FASEB journal | | | 2008 | 618 | 0 |
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| Reduced insulin secretion and content in VEGF-a deficient mouse pancreatic islets | Experimental and clinical endocrinology & diabetes | | | 2008 | 565 | 0 |
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| The MODY1 gene for hepatocyte nuclear factor 4alpha and a feedback loop control COUP-TFII expression in pancreatic beta cells | Molecular and cellular biology | | | 2008 | 534 | 0 |
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| Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells | The Journal of biological chemistry | | | 2008 | 681 | 0 |
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| Synaptotagmins bind calcium to release insulin | American journal of physiology: endocrinology and metabolism | | | 2008 | 627 | 0 |
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| Characterization of pancreatic transcription factor Pdx-1 binding sites using promoter microarray and serial analysis of chromatin occupancy | The Journal of biological chemistry | | | 2007 | 819 | 474 |
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| Proteomics analysis of insulin secretory granules | Molecular & cellular proteomics | | | 2007 | 723 | 932 |
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| The Fas pathway is involved in pancreatic beta cell secretory function | Proceedings of the National Academy of Sciences of the United States of America | | | 2007 | 693 | 0 |
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| Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets | Genes and immunity | | | 2007 | 643 | 0 |
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| The transcription factor PAX4 acts as a survival gene in INS-1E insulinoma cells | Oncogene | | | 2007 | 676 | 0 |
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| Alpha-cells of the endocrine pancreas: 35 years of research but the enigma remains | Endocrine reviews | | | 2007 | 653 | 0 |
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| Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species | Diabetologia | | | 2007 | 747 | 290 |
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| Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins | Experimental cell research | | | 2006 | 674 | 639 |
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| [Retracted] Low concentration of interleukin-1beta induces FLICE-inhibitory protein-mediated beta-cell proliferation in human pancreatic islets | Diabetes | | | 2006 | 855 | 1,044 |
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| MicroRNAs: 'ribo-regulators' of glucose homeostasis | Nature medicine | | | 2006 | 565 | 1,067 |
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| Minireview: implication of mitochondria in insulin secretion and action | Endocrinology | | | 2006 | 623 | 463 |
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| SV2A and SV2C are not vesicular Ca2+ transporters but control glucose-evoked granule recruitment | Journal of cell science | | | 2005 | 572 | 715 |
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| Adenovirus-mediated silencing of synaptotagmin 9 inhibits Ca2+-dependent insulin secretion in islets | FEBS letters | | | 2005 | 598 | 477 |
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| Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells | Diabetologia | | | 2005 | 657 | 240 |
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| Does chasing selected 'Fox' to the nucleus prevent diabetes? | Trends in molecular medicine | | | 2005 | 657 | 572 |
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| The HNF-1 target collectrin controls insulin exocytosis by SNARE complex formation | Cell metabolism | | | 2005 | 599 | 768 |
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| The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human islets | The Journal of cell biology | | | 2004 | 609 | 731 |
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| Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells | Endocrinology | | | 2004 | 483 | 0 |
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| GABA in the endocrine pancreas: its putative role as an islet cell paracrine-signalling molecule | The Journal of general physiology | | | 2004 | 549 | 404 |
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| Beta-cell-targeted expression of a dominant-negative mutant of hepatocyte nuclear factor-1alpha in mice: diabetes model with beta-cell dysfunction partially rescued by nonglucose secretagogues | Diabetes | | | 2004 | 564 | 459 |
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| Gene expression profiles during beta cell maturation and after IL-1beta exposure reveal important roles of Pdx-1 and Nkx6.1 for IL-1beta sensitivity | Diabetologia | | | 2004 | 623 | 214 |
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| Islet β-cell secretion determines glucagon release from neighbouring α-cells | Nature cell biology | | | 2003 | 634 | 0 |
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| Impaired insulin secretion and glucose tolerance in beta cell-selective Ca(v)1.2 Ca2+ channel null mice | EMBO journal | | | 2003 | 608 | 508 |
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| Dominant-negative suppression of HNF-1 alpha results in mitochondrial dysfunction, INS-1 cell apoptosis, and increased sensitivity to ceramide-, but not to high glucose-induced cell death | The Journal of biological chemistry | | | 2002 | 599 | 408 |
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| Foxa2 (HNF3beta) controls multiple genes implicated in metabolism-secretion coupling of glucose-induced insulin release | The Journal of biological chemistry | | | 2002 | 571 | 381 |
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| Mitochondrial metabolism sets the maximal limit of fuel-stimulated insulin secretion in a model pancreatic beta cell: a survey of four fuel secretagogues | The Journal of biological chemistry | | | 2002 | 634 | 482 |
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| Mitochondria respond to Ca2+ already in the submicromolar range: correlation with redox state | Cell calcium | | | 2002 | 610 | 854 |
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| Expression and localisation of synaptotagmin isoforms in endocrine beta-cells: their function in insulin exocytosis | Journal of cell science | | | 2001 | 583 | 300 |
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| Von Willebrand factor propeptide as a marker of disease activity in systemic sclerosis (scleroderma) | Arthritis research & therapy | | | 2001 | 510 | 193 |
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| Increased intracellular calcium is required for spreading of rat islet beta-cells on extracellular matrix | Diabetes | | | 2001 | 613 | 0 |
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| GAD65-mediated glutamate decarboxylation reduces glucose-stimulated insulin secretion in pancreatic beta cells | The Journal of biological chemistry | | | 2001 | 584 | 304 |
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| Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice | Endocrinology | | | 2001 | 633 | 0 |
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| Mitochondrial calcium oscillations in C2C12 myotubes | The Journal of biological chemistry | | | 2001 | 592 | 0 |
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| Mitochondrial function in normal and diabetic beta-cells | Nature | | | 2001 | 610 | 1,300 |
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| A neuronal isoform of nitric oxide synthase expressed in pancreatic beta-cells controls insulin secretion | Diabetes | | | 2001 | 633 | 0 |
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| Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance | The Journal of clinical investigation | | | 2000 | 582 | 0 |
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| The Rab3-interacting molecule RIM is expressed in pancreatic beta-cells and is implicated in insulin exocytosis | FEBS letters | | | 2000 | 633 | 522 |
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| Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells | The Journal of biological chemistry | | | 1999 | 617 | 666 |
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| Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells | The Journal of clinical investigation | | | 1999 | 642 | 423 |
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| Autocrine regulation of endothelial exocytosis: von Willebrand factor release is induced by prostacyclin in cultured endothelial cells | FEBS letters | | | 1998 | 620 | 695 |
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