| Regulated and adaptive in vivo insulin secretion from islets only containing β-cells | Nature metabolism |  | | 2024 | 82 | 30 |
|
| Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption | Communications biology | | | 2024 | 29 | 10 |
|
| Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors | Cell stem cell |  | | 2023 | 51 | 0 |
|
| Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production | Trends in Cell Biology | | | 2023 | 94 | 3 |
|
| Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes | Scientific reports | | | 2022 | 128 | 101 |
|
| Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells | Cell reports | | | 2022 | 234 | 239 |
|
| Generation of human islet cell type-specific identity genesets | Nature communications | | | 2022 | 166 | 165 |
|
| Ultrafast pulse shaping modulates perceived visual brightness in living animals | Science Advances | | | 2021 | 392 | 152 |
|
| The RB611 recombinant antibody recognizes human and murine pancreatic polypeptide by immunofluorescence | Antibody reports | | | 2021 | 182 | 52 |
|
| Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss | BMC Genomics | | | 2021 | 214 | 108 |
|
| Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production | Nature Communications | | | 2021 | 249 | 130 |
|
| RB608, RB609, RB610, RB611 and RB612 antibodies recognize murine pancreatic polypeptide by ELISA | Antibody reports | | | 2021 | 126 | 64 |
|
| Cell heterogeneity and paracrine interactions in human islet function: a perspective focused in β-cell regeneration strategies | Frontiers in Endocrinology | | | 2021 | 280 | 324 |
|
| SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans | Molecular Metabolism | | | 2020 | 242 | 122 |
|
| Generation and characterization of a novel mouse model that allows spatiotemporal quantification of pancreatic β-cell proliferation | Diabetes | | | 2020 | 306 | 302 |
|
| Combined inhibition of menin-MLL interaction and TGF-β signaling induces replication of human pancreatic beta cells | European Journal of Cell Biology | | | 2020 | 439 | 3 |
|
| GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells | Scientific Reports | | | 2019 | 280 | 139 |
|
| Tissue repair brakes: a common paradigm in the biology of regeneration | Stem Cells | | | 2019 | 316 | 1 |
|
| Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells | Nature | | | 2019 | 687 | 12 |
|
| A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry | Cell Metabolism | | | 2019 | 540 | 4 |
|
| Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells | Nature Cell Biology | | | 2018 | 499 | 7 |
|
| β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion | Cell Reports | | | 2018 | 577 | 251 |
|
| α-cell glucokinase suppresses glucose-regulated glucagon secretion | Nature Communications | | | 2018 | 514 | 220 |
|
| Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis | Cell reports | | | 2017 | 486 | 345 |
|
| Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes | Scientific Reports | | | 2017 | 454 | 196 |
|
| Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells into β-Cells in Vivo | Diabetes | | | 2017 | 515 | 253 |
|
| Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx | Cell metabolism | | | 2017 | 582 | 361 |
|
| Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice | Diabetologia | | | 2017 | 467 | 189 |
|
| Insulin and Glucagon: Partners for Life | Endocrinology | | | 2017 | 576 | 403 |
|
| Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis | International journal of biochemistry & cell biology | | | 2017 | 467 | 1 |
|
| Stress-impaired transcription factor expression and insulin secretion in transplanted human islets | The Journal of clinical investigation | | | 2016 | 623 | 2 |
|
| Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells | Diabetes | | | 2016 | 546 | 347 |
|
| Stress-induced adaptive islet cell identity changes | Diabetes, obesity & metabolism | | | 2016 | 442 | 1 |
|
| Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion | Current opinion in genetics & development | | | 2016 | 502 | 4 |
|
| Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production | Diabetologia | | | 2016 | 462 | 0 |
|
| A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells | PloS one | | | 2016 | 581 | 232 |
|
| Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist | eLife | | | 2016 | 543 | 294 |
|
| Role of the type 2 diabetes genome-wide association studies gene SLC30A8 in the pancreatic alpha cell | Diabetologia | | | 2015 | 416 | 0 |
|
| A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT | Molecular imaging and biology | | | 2015 | 508 | 2 |
|
| LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia | Molecular metabolism | | | 2015 | 529 | 222 |
|
| Connective Tissue Growth Factor Modulates Adult β-Cell Maturity and Proliferation to Promote β-Cell Regeneration in Mice | Diabetes | | | 2015 | 616 | 2 |
|
| Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice | Diabetologia | | | 2015 | 671 | 269 |
|
| The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion | The Journal of biological chemistry | | | 2015 | 533 | 228 |
|
| Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rgnull RIP-DTR mice engrafted with human islets | Diabetes, metabolic syndrome and obesity | | | 2015 | 635 | 538 |
|
| Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers | Nature | | | 2014 | 771 | 860 |
|
| Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes | Diabetes | | | 2014 | 497 | 731 |
|
| Argonaute2 mediates compensatory expansion of the pancreatic β cell | Cell metabolism | | | 2014 | 564 | 472 |
|
| In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion | Diabetes | | | 2013 | 574 | 0 |
|
| UCP2 regulates the glucagon response to fasting and starvation | Diabetes | | | 2013 | 550 | 594 |
|
| Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development | Diabetes | | | 2013 | 612 | 3 |
|
| An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice | Molecular endocrinology | | | 2013 | 676 | 676 |
|
| Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice | PLOS genetics | | | 2013 | 725 | 370 |
|
| Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity | PLOS genetics | | | 2013 | 673 | 305 |
|
| Nogo-A downregulation improves insulin secretion in mice | Diabetes | | | 2013 | 667 | 270 |
|
| Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin | Cell metabolism | | | 2013 | 705 | 4 |
|
| PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice | The Journal of clinical investigation | | | 2012 | 798 | 719 |
|
| The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice | Gastroenterology | | | 2012 | 683 | 606 |
|
| Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme | Gene expression patterns | | | 2011 | 651 | 512 |
|
| Progenitor cell domains in the developing and adult pancreas | Cell cycle | | | 2011 | 621 | 243 |
|
| Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance | Molecular endocrinology | | | 2011 | 518 | 525 |
|
| In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice | Diabetes | | | 2011 | 673 | 1,576 |
|
| Dicer is required for haploid male germ cell differentiation in mice | PloS one | | | 2011 | 528 | 311 |
|
| Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands | Proceedings of the National Academy of Sciences of the United States of America | | | 2011 | 726 | 303 |
|
| Context-specific α- to-β-cell reprogramming by forced Pdx1 expression | Genes & development | | | 2011 | 633 | 340 |
|
| β-cell regeneration: the pancreatic intrinsic faculty | Trends in endocrinology and metabolism | | | 2011 | 661 | 709 |
|
| Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice | Diabetes | | | 2011 | 636 | 348 |
|
| Pancreatic beta cells require NeuroD to achieve and maintain functional maturity | Cell metabolism | | | 2010 | 559 | 13 |
|
| Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss | Nature | | | 2010 | 674 | 6 |
|
| Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development | Gastroenterology | | | 2010 | 594 | 3 |
|
| Génération de cellules béta-pancréatiques par conversion spontanée de cellules alpha chez des souris diabétiques | MS. Médecine sciences | | | 2010 | 531 | 4 |
|
| The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression | Diabetes | | | 2010 | 598 | 0 |
|
| Bcl-2 overexpression in type II epithelial cells does not prevent hyperoxia-induced acute lung injury in mice | American journal of physiology. Lung cellular and molecular physiology | | | 2010 | 643 | 4 |
|
| Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice | Gastroenterology | | | 2009 | 583 | 1 |
|
| Pancreatic neurogenin 3-expressing cells are unipotent islet precursors | Development | | | 2009 | 548 | 0 |
|
| Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis | The Journal of biological chemistry | | | 2009 | 521 | 0 |
|
| Transgenic and other experimental models of pancreas and islet damage | Diabetes, obesity & metabolism | | | 2009 | 517 | 4 |
|
| Insulin signaling in alpha cells modulates glucagon secretion in vivo | Cell metabolism | | | 2009 | 613 | 335 |
|
| Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice | The Journal of clinical investigation | | | 2009 | 548 | 0 |
|
| Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate | Proceedings of the National Academy of Sciences of the United States of America | | | 2008 | 610 | 0 |
|
| Experimental models of beta-cell regeneration | Biochemical Society transactions | | | 2008 | 643 | 670 |
|
| Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes | GLIA | | | 2008 | 609 | 11 |
|
| A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells | Experimental cell research | | | 2008 | 640 | 2 |
|
| Genes controlling pancreas ontogeny | The International journal of developmental biology | | | 2008 | 579 | 1 |
|
| Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice | Diabetologia | | | 2007 | 593 | 2 |
|
| Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas | Development | | | 2007 | 570 | 0 |
|
| The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells | FEBS letters | | | 2007 | 404 | 0 |
|
| Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression | The Journal of clinical investigation | | | 2007 | 535 | 1 |
|
| Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species | Diabetologia | | | 2007 | 631 | 165 |
|
| Stabilization of beta-catenin impacts pancreas growth | Development | | | 2006 | 500 | 0 |
|
| An amylase/Cre transgene marks the whole endoderm but the primordia of liver and ventral pancreas | Genesis | | | 2006 | 619 | 0 |
|
| Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas | American journal of physiology: endocrinology and metabolism | | | 2006 | 566 | 0 |
|
| Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass | Nature genetics | | | 2006 | 515 | 0 |
|
| Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis | Diabetologia | | | 2005 | 501 | 0 |
|
| Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation | The Journal of immunology | | | 2005 | 559 | 0 |
|
| Foxa2 is required for the differentiation of pancreatic alpha-cells | Developmental biology | | | 2005 | 561 | 0 |
|
| Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin and glucagon content | European journal of endocrinology | | | 2004 | 639 | 0 |
|
| Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets | Experimental cell research | | | 2004 | 662 | 2 |
|
| Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes | Diabetes | | | 2004 | 584 | 0 |
|
| Nestin expression in pancreatic exocrine cell lineages | Mechanisms of development | | | 2004 | 540 | 0 |
|
| Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes | Developmental biology | | | 2004 | 522 | 1 |
|
| Dissecting the role of glucocorticoids on pancreas development | Diabetes | | | 2004 | 572 | 0 |
|
| Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice | Cancer research | | | 2003 | 506 | 1 |
|
| Islet β-cell secretion determines glucagon release from neighbouring α-cells | Nature cell biology | | | 2003 | 570 | 0 |
|
| Pancreatic cell lineage analyses in mice | Endocrine | | | 2002 | 577 | 328 |
|
| Defining the cell lineages of the islets of Langerhans using transgenic mice | The International journal of developmental biology | | | 2002 | 503 | 2 |
|
| Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor | The Journal of clinical investigation | | | 2002 | 483 | 0 |
|
| Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1 | British journal of cancer | | | 2002 | 466 | 9 |
|
| Generation of Smad4/Dpc4 conditional knockout mice | Genesis | | | 2002 | 568 | 0 |
|
| Experimental models of transcription factor-associated maturity-onset diabetes of the young | Diabetes | | | 2002 | 633 | 0 |
|
| General and conditional replacement of connexin43-coding DNA by a lacZ reporter gene for cell-autonomous analysis of expression | Cell communication & adhesion | | | 2001 | 559 | 6 |
|
| Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice | Endocrinology | | | 2001 | 568 | 0 |
|
| Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages | Development | | | 2000 | 509 | 1 |
|
| A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF | Proceedings of the National Academy of Sciences of the United States of America | | | 2000 | 523 | 10 |
|
| Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance | The Journal of clinical investigation | | | 2000 | 522 | 0 |
|
| Inducible and irreversible control of gene expression using a single transgene | Nucleic acids research | | | 2000 | 657 | 203 |
|
| Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter | Genesis | | | 2000 | 558 | 0 |
|
| Modulation of an early and lethal autoimmune diabetes in transgenic mice by IL-4 overexpression and treatment with anti-IFN-γ antibody | Transgenics | | | 1999 | 262 | 126 |
|
| Two transgenic approaches to define the cell lineages in endocrine pancreas development | Molecular and cellular endocrinology | | | 1998 | 594 | 1 |
|
| TGF-β1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-α, triggers insulin-dependent diabetes | Biochemical and biophysical research communications | | | 1995 | 612 | 0 |
|
| Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes | Proceedings of the National Academy of Sciences of the United States of America | | | 1994 | 604 | 1 |
|
| A CD8+ T-lymphocyte-mediated and CD4+ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice | Diabetologia | | | 1994 | 651 | 0 |
|
| TGF-β1 influences the relative development of the exocrine and endocrine pancreas in vitro | Development | | | 1994 | 565 | 0 |
|
| Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha | The Journal of immunology | | | 1993 | 460 | 0 |
|
| Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes | The Journal of experimental medicine | | | 1992 | 630 | 0 |
|
| Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene | Development | | | 1991 | 425 | 0 |
|
| Critères pour la détermination des phalanges du cerf Elaphe (Cervus Elaphus L.) | Revue de Paléobiologie | | | 1990 | 263 | 196 |
|
| Différences entre les dents jugales deciduales du cerf Elaphe (Cervus Elaphus L.) et du boeuf domestique (Bos Taurus L.) | Revue de Paléobiologie | | | 1989 | 266 | 199 |
|
