Herrera, Pedro Luis

Title	Published in	Year	Views	Downloads
Regulated and adaptive in vivo insulin secretion from islets only containing β-cells	Nature metabolism	2024	177	256
Moderate beta-cell ablation triggers synergic compensatory mechanisms even in the absence of overt metabolic disruption	Communications biology	2024	74	42
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors	Cell stem cell	2023	99	0
Glucagon-producing α-cell transcriptional identity and reprogramming towards insulin production	Trends in cell biology	2023	137	3
Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes	Scientific reports	2022	182	398
Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells	Cell reports	2022	290	363
Generation of human islet cell type-specific identity genesets	Nature communications	2022	228	750
Ultrafast pulse shaping modulates perceived visual brightness in living animals	Science Advances	2021	460	245
The RB611 recombinant antibody recognizes human and murine pancreatic polypeptide by immunofluorescence	Antibody reports	2021	229	99
Stage-specific transcriptomic changes in pancreatic α-cells after massive β-cell loss	BMC Genomics	2021	285	201
Pancreatic Ppy-expressing γ-cells display mixed phenotypic traits and the adaptive plasticity to engage insulin production	Nature Communications	2021	334	161
RB608, RB609, RB610, RB611 and RB612 antibodies recognize murine pancreatic polypeptide by ELISA	Antibody reports	2021	173	92
Cell heterogeneity and paracrine interactions in human islet function: a perspective focused in β-cell regeneration strategies	Frontiers in Endocrinology	2021	330	414
SGLT2 is not expressed in pancreatic α- and β-cells, and its inhibition does not directly affect glucagon and insulin secretion in rodents and humans	Molecular Metabolism	2020	316	164
Generation and characterization of a novel mouse model that allows spatiotemporal quantification of pancreatic β-cell proliferation	Diabetes	2020	377	525
Combined inhibition of menin-MLL interaction and TGF-β signaling induces replication of human pancreatic beta cells	European Journal of Cell Biology	2020	489	3
GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells	Scientific Reports	2019	315	247
Tissue repair brakes: a common paradigm in the biology of regeneration	Stem Cells	2019	365	1
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells	Nature	2019	764	12
A Map of Human Type 1 Diabetes Progression by Imaging Mass Cytometry	Cell Metabolism	2019	603	4
Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells	Nature Cell Biology	2018	549	7
β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion	Cell Reports	2018	612	328
α-cell glucokinase suppresses glucose-regulated glucagon secretion	Nature Communications	2018	560	291
Pancreatic α Cell-Derived Glucagon-Related Peptides Are Required for β Cell Adaptation and Glucose Homeostasis	Cell reports	2017	538	421
Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes	Scientific Reports	2017	505	214
Mafa Enables Pdx1 to Effectively Convert Pancreatic Islet Progenitors and Committed Islet α-Cells into β-Cells in Vivo	Diabetes	2017	578	308
Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx	Cell metabolism	2017	643	361
Pancreatic alpha cell-selective deletion of Tcf7l2 impairs glucagon secretion and counter-regulatory responses to hypoglycaemia in mice	Diabetologia	2017	511	286
Insulin and Glucagon: Partners for Life	Endocrinology	2017	639	482
Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis	International journal of biochemistry & cell biology	2017	512	1
Stress-impaired transcription factor expression and insulin secretion in transplanted human islets	The Journal of clinical investigation	2016	669	2
Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine β-Cells	Diabetes	2016	599	381
Stress-induced adaptive islet cell identity changes	Diabetes, obesity & metabolism	2016	489	1
Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion	Current opinion in genetics & development	2016	537	4
Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production	Diabetologia	2016	512	0
A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells	PloS one	2016	633	251
Blockade of glucagon signaling prevents or reverses diabetes onset only if residual β-cells persist	eLife	2016	590	385
Role of the type 2 diabetes genome-wide association studies gene SLC30A8 in the pancreatic alpha cell	Diabetologia	2015	462	0
A standardized method for in vivo mouse pancreas imaging and semiquantitative β cell mass measurement by dual isotope SPECT	Molecular imaging and biology	2015	538	2
LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia	Molecular metabolism	2015	563	304
Connective Tissue Growth Factor Modulates Adult β-Cell Maturity and Proliferation to Promote β-Cell Regeneration in Mice	Diabetes	2015	667	2
Targeting GLP-1 receptors for repeated magnetic resonance imaging differentiates graded losses of pancreatic beta cells in mice	Diabetologia	2015	746	333
The Zinc Transporter Slc30a8/ZnT8 Is Required in a Subpopulation of Pancreatic α-Cells for Hypoglycemia-induced Glucagon Secretion	The Journal of biological chemistry	2015	596	289
Lixisenatide accelerates restoration of normoglycemia and improves human beta-cell function and survival in diabetic immunodeficient NOD-scid IL-2rgnull RIP-DTR mice engrafted with human islets	Diabetes, metabolic syndrome and obesity	2015	684	570
Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers	Nature	2014	861	920
Glycoprotein 130 receptor signaling mediates α-cell dysfunction in a rodent model of type 2 diabetes	Diabetes	2014	556	839
Argonaute2 mediates compensatory expansion of the pancreatic β cell	Cell metabolism	2014	622	533
In situ electrophysiological examination of pancreatic α cells in the streptozotocin-induced diabetes model, revealing the cellular basis of glucagon hypersecretion	Diabetes	2013	624	0
UCP2 regulates the glucagon response to fasting and starvation	Diabetes	2013	583	659
Loss of prohibitin induces mitochondrial damages altering β-cell function and survival and is responsible for gradual diabetes development	Diabetes	2013	662	4
An Essential Role for Insulin and IGF1 Receptors in Regulating Sertoli Cell Proliferation, Testis Size, and FSH Action in Mice	Molecular endocrinology	2013	743	885
Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice	PLOS genetics	2013	760	403
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity	PLOS genetics	2013	725	497
Nogo-A downregulation improves insulin secretion in mice	Diabetes	2013	711	353
Leptin engages a hypothalamic neurocircuitry to permit survival in the absence of insulin	Cell metabolism	2013	766	4
PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice	The Journal of clinical investigation	2012	867	786
The zinc finger protein ZBTB20 regulates transcription of fructose-1,6-bisphosphatase 1 and β cell function in mice	Gastroenterology	2012	735	758
Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme	Gene expression patterns	2011	692	662
Progenitor cell domains in the developing and adult pancreas	Cell cycle	2011	671	360
Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance	Molecular endocrinology	2011	561	552
In vivo conditional Pax4 overexpression in mature islet β-cells prevents stress-induced hyperglycemia in mice	Diabetes	2011	709	1,593
Dicer is required for haploid male germ cell differentiation in mice	PloS one	2011	579	352
Multimodal image coregistration and inducible selective cell ablation to evaluate imaging ligands	Proceedings of the National Academy of Sciences of the United States of America	2011	798	361
Context-specific α- to-β-cell reprogramming by forced Pdx1 expression	Genes & development	2011	676	520
β-cell regeneration: the pancreatic intrinsic faculty	Trends in endocrinology and metabolism	2011	720	1,131
Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice	Diabetes	2011	676	397
Pancreatic beta cells require NeuroD to achieve and maintain functional maturity	Cell metabolism	2010	813	220
Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss	Nature	2010	750	6
Alpha cell-specific Men1 ablation triggers the transdifferentiation of glucagon-expressing cells and insulinoma development	Gastroenterology	2010	644	3
Génération de cellules béta-pancréatiques par conversion spontanée de cellules alpha chez des souris diabétiques	MS. Médecine sciences	2010	565	4
The transcription factor Rfx3 regulates beta-cell differentiation, function, and glucokinase expression	Diabetes	2010	651	0
Bcl-2 overexpression in type II epithelial cells does not prevent hyperoxia-induced acute lung injury in mice	American journal of physiology. Lung cellular and molecular physiology	2010	688	4
Pancreatic inactivation of c-Myc decreases acinar mass and transdifferentiates acinar cells into adipocytes in mice	Gastroenterology	2009	646	1
Pancreatic neurogenin 3-expressing cells are unipotent islet precursors	Development	2009	589	0
Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis	The Journal of biological chemistry	2009	568	0
Transgenic and other experimental models of pancreas and islet damage	Diabetes, obesity & metabolism	2009	560	43
Insulin signaling in alpha cells modulates glucagon secretion in vivo	Cell metabolism	2009	672	492
Deletion of the von Hippel-Lindau gene in pancreatic beta cells impairs glucose homeostasis in mice	The Journal of clinical investigation	2009	604	0
Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate	Proceedings of the National Academy of Sciences of the United States of America	2008	661	0
Experimental models of beta-cell regeneration	Biochemical Society transactions	2008	693	821
Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes	GLIA	2008	667	11
A new conditional mouse mutant reveals specific expression and functions of connexin36 in neurons and pancreatic beta-cells	Experimental cell research	2008	674	2
Genes controlling pancreas ontogeny	The International journal of developmental biology	2008	624	1
Pancreatic deletion of insulin receptor substrate 2 reduces beta and alpha cell mass and impairs glucose homeostasis in mice	Diabetologia	2007	642	27
Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas	Development	2007	629	0
The GluCre-ROSA26EYFP mouse: a new model for easy identification of living pancreatic alpha-cells	FEBS letters	2007	456	0
Embryonic endocrine pancreas and mature beta cells acquire alpha and PP cell phenotypes upon Arx misexpression	The Journal of clinical investigation	2007	621	1
Increasing uncoupling protein-2 in pancreatic beta cells does not alter glucose-induced insulin secretion but decreases production of reactive oxygen species	Diabetologia	2007	739	270
Stabilization of beta-catenin impacts pancreas growth	Development	2006	560	0
An amylase/Cre transgene marks the whole endoderm but the primordia of liver and ventral pancreas	Genesis	2006	669	0
Activation of the Reg family genes by pancreatic-specific IGF-I gene deficiency and after streptozotocin-induced diabetes in mouse pancreas	American journal of physiology: endocrinology and metabolism	2006	612	0
Ablation of PDK1 in pancreatic beta cells induces diabetes as a result of loss of beta cell mass	Nature genetics	2006	599	0
Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis	Diabetologia	2005	551	0
Junctional adhesion molecule-C regulates the early influx of leukocytes into tissues during inflammation	The Journal of immunology	2005	599	0
Foxa2 is required for the differentiation of pancreatic alpha-cells	Developmental biology	2005	619	0
Pax2 mutant mice display increased number and size of islets of Langerhans but no change in insulin and glucagon content	European journal of endocrinology	2004	705	0
Replacement by a lacZ reporter gene assigns mouse connexin36, 45 and 43 to distinct cell types in pancreatic islets	Experimental cell research	2004	718	2
Pancreatic-specific inactivation of IGF-I gene causes enlarged pancreatic islets and significant resistance to diabetes	Diabetes	2004	632	0
Nestin expression in pancreatic exocrine cell lineages	Mechanisms of development	2004	607	0
Conditional inactivation of Pax6 in the pancreas causes early onset of diabetes	Developmental biology	2004	579	1
Dissecting the role of glucocorticoids on pancreas development	Diabetes	2004	630	0
Pancreatic beta-cell-specific ablation of the multiple endocrine neoplasia type 1 (MEN1) gene causes full penetrance of insulinoma development in mice	Cancer research	2003	561	1
Islet β-cell secretion determines glucagon release from neighbouring α-cells	Nature cell biology	2003	626	0
Pancreatic cell lineage analyses in mice	Endocrine	2002	631	436
Defining the cell lineages of the islets of Langerhans using transgenic mice	The International journal of developmental biology	2002	581	2
Defective insulin secretion in pancreatic beta cells lacking type 1 IGF receptor	The Journal of clinical investigation	2002	545	0
Reduced PTEN expression in the pancreas overexpressing transforming growth factor-beta 1	British journal of cancer	2002	520	48
Generation of Smad4/Dpc4 conditional knockout mice	Genesis	2002	618	0
Experimental models of transcription factor-associated maturity-onset diabetes of the young	Diabetes	2002	679	0
General and conditional replacement of connexin43-coding DNA by a lacZ reporter gene for cell-autonomous analysis of expression	Cell communication & adhesion	2001	614	73
Beta-cell-targeted expression of a dominant-negative hepatocyte nuclear factor-1 alpha induces a maturity-onset diabetes of the young (MODY)3-like phenotype in transgenic mice	Endocrinology	2001	626	0
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages	Development	2000	559	2
A mouse CD8 T cell-mediated acute autoimmune diabetes independent of the perforin and Fas cytotoxic pathways: possible role of membrane TNF	Proceedings of the National Academy of Sciences of the United States of America	2000	565	68
Junctional communication of pancreatic beta cells contributes to the control of insulin secretion and glucose tolerance	The Journal of clinical investigation	2000	575	0
Inducible and irreversible control of gene expression using a single transgene	Nucleic acids research	2000	694	322
Mosaic Cre-mediated recombination in pancreas using the pdx-1 enhancer/promoter	Genesis	2000	597	1
Modulation of an early and lethal autoimmune diabetes in transgenic mice by IL-4 overexpression and treatment with anti-IFN-γ antibody	Transgenics	1999	305	204
Two transgenic approaches to define the cell lineages in endocrine pancreas development	Molecular and cellular endocrinology	1998	627	1
TGF-β1 overexpression in murine pancreas induces chronic pancreatitis and, together with TNF-α, triggers insulin-dependent diabetes	Biochemical and biophysical research communications	1995	668	0
Ablation of islet endocrine cells by targeted expression of hormone-promoter-driven toxigenes	Proceedings of the National Academy of Sciences of the United States of America	1994	638	1
A CD8⁺ T-lymphocyte-mediated and CD4⁺ T-lymphocyte-independent autoimmune diabetes of early onset in transgenic mice	Diabetologia	1994	685	0
TGF-β1 influences the relative development of the exocrine and endocrine pancreas in vitro	Development	1994	616	0
Induction of diabetes is influenced by the infectious virus and local expression of MHC class I and tumor necrosis factor-alpha	The Journal of immunology	1993	510	0
Expression of a tumor necrosis factor alpha transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes	The Journal of experimental medicine	1992	696	0
Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene	Development	1991	467	0
Critères pour la détermination des phalanges du cerf Elaphe (Cervus Elaphus L.)	Revue de Paléobiologie	1990	300	504
Différences entre les dents jugales deciduales du cerf Elaphe (Cervus Elaphus L.) et du boeuf domestique (Bos Taurus L.)	Revue de Paléobiologie	1989	312	336