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Title

Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer

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Published in Swiss Medical Weekly. 2011, vol. 141, w13249
Abstract There are very limited data suggesting a benefit for second-line chemotherapy in advanced gastric cancer. Therefore, the number of patients who receive further treatment after failure of first-line chemotherapy varies considerably, ranging from 14% to 75%. In the absence of a demonstrated survival benefit of second-line chemotherapy, appropriate selection of patients based on survival predictors is essential. However, no clinico-pathologic parameters are currently widely adopted in clinical practice. We looked exclusively at Caucasian patients with metastatic gastric cancer treated with second-line chemotherapy to see if we could establish prognostic factors for survival.
Keywords AdultAgedAntineoplastic Combined Chemotherapy Protocols/therapeutic useCarcinoembryonic Antigen/bloodDisease-Free SurvivalEuropean Continental Ancestry GroupFemaleHumansMaleMiddle AgedNeoplasm MetastasisPrognosisProportional Hazards ModelsRetrospective StudiesStomach Neoplasms/drug therapy/pathology/surgery
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PMID: 21870299
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Article (Published version) (302 Kb) - public document Free access
Structures
Research groups Chirurgie viscérale (104)
Chirurgie viscérale (HUG)
Epidémiologie clinique (115)
Groupe Roth Arnaud (oncologie) (285)
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BOHANES, Pierre et al. Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer. In: Swiss Medical Weekly, 2011, vol. 141, p. w13249. doi: 10.4414/smw.2011.13249 https://archive-ouverte.unige.ch/unige:24808

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Deposited on : 2012-12-20

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