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Scientific article
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Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer

Published inSchweizerische medizinische Wochenschrift, vol. 141, w13249
Publication date2011
Abstract

There are very limited data suggesting a benefit for second-line chemotherapy in advanced gastric cancer. Therefore, the number of patients who receive further treatment after failure of first-line chemotherapy varies considerably, ranging from 14% to 75%. In the absence of a demonstrated survival benefit of second-line chemotherapy, appropriate selection of patients based on survival predictors is essential. However, no clinico-pathologic parameters are currently widely adopted in clinical practice. We looked exclusively at Caucasian patients with metastatic gastric cancer treated with second-line chemotherapy to see if we could establish prognostic factors for survival.

Keywords
  • Adult
  • Aged
  • Antineoplastic Combined Chemotherapy Protocols/therapeutic use
  • Carcinoembryonic Antigen/blood
  • Disease-Free Survival
  • European Continental Ancestry Group
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neoplasm Metastasis
  • Prognosis
  • Proportional Hazards Models
  • Retrospective Studies
  • Stomach Neoplasms/drug therapy/pathology/surgery
Citation (ISO format)
BOHANES, Pierre et al. Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer. In: Schweizerische medizinische Wochenschrift, 2011, vol. 141, p. w13249. doi: 10.4414/smw.2011.13249
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Article (Published version)
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ISSN of the journal0036-7672
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