Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer

Article Article scientifique Article Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer eng 2011 author Bohanes Pierre 704659 author Courvoisier Delphine 0000-0002-1956-2607 94475 author Perneger Thomas 28462 author Morel Philippe 22337 author Huber Olivier 50133 author Roth Arnaud 134504 w13249 10.4414/smw.2011.13249 21870299 0036-7672 There are very limited data suggesting a benefit for second-line chemotherapy in advanced gastric cancer. Therefore, the number of patients who receive further treatment after failure of first-line chemotherapy varies considerably, ranging from 14% to 75%. In the absence of a demonstrated survival benefit of second-line chemotherapy, appropriate selection of patients based on survival predictors is essential. However, no clinico-pathologic parameters are currently widely adopted in clinical practice. We looked exclusively at Caucasian patients with metastatic gastric cancer treated with second-line chemotherapy to see if we could establish prognostic factors for survival. Adult Aged Antineoplastic Combined Chemotherapy Protocols/therapeutic use Carcinoembryonic Antigen/blood Disease-Free Survival European Continental Ancestry Group Female Humans Male Middle Aged Neoplasm Metastasis Prognosis Proportional Hazards Models Retrospective Studies Stomach Neoplasms/drug therapy/pathology/surgery Dewey 616 Dewey 617 56 Département de médecine 221 57 Département de chirurgie 222 false 79 Chirurgie viscérale 104 1329 Chirurgie viscérale (HUG) 88 Epidémiologie clinique 115 223 Groupe Roth Arnaud (oncologie) 285 Schweizerische medizinische Wochenschrift 141 a6b3976b-d2bd-4937-9aea-5a59f2887fdb Article (Published version) Public 2011_bohanes_swiss_med_wkly.pdf 309009 application/pdf openAccess Faculté de médecine / Section de médecine clinique / Département de médecine Faculté de médecine / Section de médecine clinique / Département de chirurgie

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Facteurs prédictifs de longue survie chez les patients Caucasiens atteints de cancer de l'estomac métastatique traité par une 2ème ligne de chimiothérapie		2014	931	810
Survival predictors for second-line chemotherapy in Caucasian patients with metastatic gastric cancer	Schweizerische medizinische Wochenschrift	2011	778	360

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Bohanes, Pierre