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Scientific article
Open access
English

Humanlectome, an update of unilectin for the annotation and prediction of human lectins

Published inNucleic acids research, vol. 52, no. D1, p. D1683-D1693
Publication date2024-01-05
First online date2023-10-27
Abstract

The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (https://unilectin.unige.ch/humanLectome/), covering our knowledge of the human lectome and comprising 215 unevenly characterised lectins, particularly in terms of structural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-structure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined.

eng
Funding
  • French National Research Agency (ANR) - CBH-EUR-GS [ANR-17-EURE-0003]
  • French National Research Agency (ANR) - Glyco@Alps [ANR-15-IDEX-02]
Citation (ISO format)
SCHNIDER, Boris et al. Humanlectome, an update of unilectin for the annotation and prediction of human lectins. In: Nucleic acids research, 2024, vol. 52, n° D1, p. D1683–D1693. doi: 10.1093/nar/gkad905
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Article (Published version)
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ISSN of the journal0305-1048
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Creation01/24/2024 12:07:39 PM
First validation02/29/2024 1:35:20 PM
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