Humanlectome, an update of unilectin for the annotation and prediction of human lectins

Article Article scientifique Article Humanlectome, an update of unilectin for the annotation and prediction of human lectins eng 2023-10-27 2024-01-05 author Schnider Boris 404342 Département d'informatique (DINFO) author M'Rad Yacine 895739 author El Ahmadie Jalaa 974609 author de Brevern Alexandre G 0000-0001-7112-5626 author Imberty Anne 0000-0001-6825-9527 author Lisacek Frédérique 0000-0002-0948-4537 639315 Département d'informatique (DINFO) D1683-D1693 10.1093/nar/gkad905 37889052 0305-1048 PMC10767822 https://academic.oup.com/nar/article/52/D1/D1683/7331022 The UniLectin portal (https://unilectin.unige.ch/) was designed in 2019 with the goal of centralising curated and predicted data on carbohydrate-binding proteins known as lectins. UniLectin is also intended as a support for the study of lectomes (full lectin set) of organisms or tissues. The present update describes the inclusion of several new modules and details the latest (https://unilectin.unige.ch/humanLectome/), covering our knowledge of the human lectome and comprising 215 unevenly characterised lectins, particularly in terms of structural information. Each HumanLectome entry is protein-centric and compiles evidence of carbohydrate recognition domain(s), specificity, 3D-structure, tissue-based expression and related genomic data. Other recent improvements regarding interoperability and accessibility are outlined. Dewey 570 Dewey 025.063 French National Research Agency (ANR) CBH-EUR-GS ANR-17-EURE-0003 CBH-EUR-GS FR French National Research Agency (ANR) Glyco@Alps ANR-15-IDEX-02 32 Département d'informatique 18 30 Section de biologie 16 13 Centre universitaire d'informatique 0D3 false 1316 Proteome informatics Group Nucleic acids research 52 D1 3a6bd37b-3d97-4055-aada-4c26921d8044 Article (Published version) Public Article-scientifique-from-crossref.pdf 1970858 application/pdf CC BY a660f0b86192aaa18cf543e032f12ab18f86426f51a2273f5d537fde04c00d9e openAccess Faculté des sciences / Département d'informatique Faculté des sciences / Section de biologie Centres et instituts / Centre universitaire d'informatique

Title	Published in	Access level	OA Policy	Year	Views	Downloads

Humanlectome, an update of unilectin for the annotation and prediction of human lectins	Nucleic acids research			2024	85	56

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El Ahmadie, Jalaa