This report addresses the most relevant data on COVID-19 vaccines literature as of 26 November 2021. The current report addresses the latest data on the new WHO EUL approved vaccine COVAXIN/BBV152, vaccine effectiveness its waning immunity and duration of protection, the vaccine-induced humoral, cellular, and neutralizing response of the Chinese inactivated vaccines, breakthrough infections, virus transmissibility, vaccine booster doses, COVID-19 vaccines in children, COVID-19 vaccine safety and myocarditis. To conclude, the report highlights the latest SARS-CoV-2 vaccine development information on COVID-19 vaccine candidates.