This report addresses the most relevant data on COVID-19 vaccines literature as of 02 November 2021. The current report addresses the latest data on vaccine effectiveness and its duration of protection, the vaccine-induced humoral, cellular, and neutralizing response over time, the effects of vaccination on transmissibility of SARS-CoV-2, vaccine booster doses, reported cases of myocarditis, the Pfizer and BioNTech vaccine in children, and the concomitant administration of the COVID-19 and Flu vaccines. To conclude, the report highlights the latest SARS-CoV-2 vaccine development information on COVID-19 vaccine candidates.