The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet
Published inTranslational Research
Publication date2020
Abstract
Keywords
- Ceramide
- Glucagon like peptide-1 receptor agonist
- Methionine-choline deficient diet
- Nonalcoholic fatty liver disease
- Nonalcoholic steatohepatitis
- Type 2 diabetes
- Inflammation
- Microbiota
Affiliation entities
- Centres et instituts / Institut de génétique et de génomique
- Faculté de médecine / Section de médecine fondamentale / Département de physiologie cellulaire et métabolisme
- Faculté de médecine / Section de médecine fondamentale / Département de pathologie et immunologie
- Faculté de médecine / Section de médecine clinique / Département de médecine
Funding
- Swiss National Science Foundation - IL-18/IL-18BP balance in the crosstalk between inflammation and metabolic homeostasis [189003]
- Swiss National Science Foundation - Roles of the pancreatic islet cell-specific circadian oscillators in metabolic regulation in physiology and type 2 diabetes [184708]
- Swiss National Science Foundation - Human muscle circadian rhythm and lipid homeostasis in physiology and insulin resistance [154405]
Citation (ISO format)
SOMM, Emmanuel et al. The GLP-1R agonist liraglutide limits hepatic lipotoxicity and inflammatory response in mice fed a methionine-choline deficient diet. In: Translational Research, 2020. doi: 10.1016/j.trsl.2020.07.008
Main files (1)
Article (Published version)
Identifiers
- PID : unige:139520
- DOI : 10.1016/j.trsl.2020.07.008
- PMID : 32711187
Journal ISSN1878-1810