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Reactive oxygen species in skeletal muscle cells: detection, modulation and implication in Duchenne muscular dystrophy

ContributorsGuedira, Ghali
Master program titleMaster en Pharmacie
Defense date2017
Abstract

Duchenne muscular dystrophy (DMD) is a X-linked genetic disease that affects 1/3500 boy. [1][2][3] It is caused by a mutation in the gene that codes for the dystrophin located on the chromosome X which leads to the absence of this protein in the affected organism. Dystrophin has a major importance in muscle cells and its absence leads to eventual muscle weakness and fragility.[2][3] The disease is characterized by progressive damage including necrosis, inflammation and fibrosis.

eng
Citation (ISO format)
GUEDIRA, Ghali. Reactive oxygen species in skeletal muscle cells: detection, modulation and implication in Duchenne muscular dystrophy. 2017.
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Master thesis
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  • PID : unige:102251
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Technical informations

Creation10/05/2017 9:52:00 AM
First validation10/05/2017 9:52:00 AM
Update time03/15/2023 7:52:27 AM
Status update03/15/2023 7:52:27 AM
Last indexation01/29/2024 9:22:47 PM
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