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Title

The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis-a prospective multi-centre European observational study

Authors
O'Dwyer, M J
Starczewska, M H
Zacharowski, K
Ecker, D J
Sampath, R
Brealey, D
Singer, M
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Published in Clinical Microbiology and Infection. 2017, vol. 23, no. 3, p. 208.e1-208.e6
Abstract Blood culture results inadequately stratify the mortality risk in critically ill patients with sepsis. We sought to establish the prognostic significance of the presence of microbial DNA in the bloodstream of patients hospitalized with suspected sepsis.
Keywords AdolescentAdultAgedAged, 80 and overBacteria/isolation & purificationBacteriological Techniques/methodsBlood/microbiologyCritical IllnessDNA, Bacterial/bloodEarly DiagnosisEuropeFemaleHumansMaleMiddle AgedMolecular Diagnostic Techniques/methodsPolymerase Chain Reaction/methodsPrognosisProspective StudiesRisk AssessmentSepsis/diagnosis/mortalitySpectrometry, Mass, Electrospray Ionization/methodsSurvival AnalysisYoung Adult
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PMID: 27890455
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Research group Analyse génomique et fonctionnelle du staphylocoque doré (604)
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O'DWYER, M J et al. The detection of microbial DNA but not cultured bacteria is associated with increased mortality in patients with suspected sepsis-a prospective multi-centre European observational study. In: Clinical Microbiology and Infection, 2017, vol. 23, n° 3, p. 208.e1-208.e6. https://archive-ouverte.unige.ch/unige:99567

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Deposited on : 2017-11-23

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