Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l’évaluation de la balance bénéfice-risque

Weisskopf, Etienne; Fumeaux, Céline J Fischer; Bickle Graz, Myriam; Harari, Mathild Morisod; Epiney, Emmanuella; Tolsa, Cristina Borradori; Rouiller-Cornu, Sylvie; Tolsa, Jean-François; Eap, Chin Bin; Vial, Yvan; Csajka, Chantal; Panchaud-Monnat, Alice

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Title		Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l’évaluation de la balance bénéfice-risque
Authors		Weisskopf, Etienne Fumeaux, Céline J Fischer Bickle Graz, Myriam Harari, Mathild Morisod Epiney, Emmanuella Tolsa, Cristina Borradori Rouiller-Cornu, Sylvie Tolsa, Jean-François Eap, Chin Bin Vial, Yvan Csajka, Chantal Panchaud-Monnat, Alice show all authors [1 - 12]
Published in		Revue médicale suisse. 2016, vol. 12, no. 510, p. 561-6
Abstract		Studies report that between 6 and 13% of women experience symptoms of depression during pregnancy and the postpartum period. The abundant data available make selective serotonin reuptake inhibitors (SSRIs) the first line treatment in pregnancy when a pharmacological treatment is required. Risks associated with the use of SSRIs during pregnancy are limited (moderate effect size) and are often not distinguishable from those inherent to the mother's disease. Yet, several questions regarding the SSRI safety profile for the unborn child are still under debate or require additional epidemiological data. The decision of SSRI use during pregnancy needs an individual evaluation of the risk-benefit balance.
Keywords		Antidepressive Agents/adverse effects/therapeutic use — Depressive Disorder/complications/drug therapy — Female — Humans — Practice Patterns, Physicians' — Pregnancy — Pregnancy Complications/chemically induced/drug therapy/psychology — Risk Assessment — Serotonin Uptake Inhibitors/adverse effects/therapeutic use
Identifiers		PMID: 27149719
Full text		Article (Published version) (574 Kb) - Limited access to UNIGE
Structures		Faculté des sciences / Section des sciences pharmaceutiques Faculté de médecine / Section de médecine clinique / Département de gynécologie et d'obstétrique
Citation (ISO format)		WEISSKOPF, Etienne et al. Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l’évaluation de la balance bénéfice-risque. In: Revue médicale suisse, 2016, vol. 12, n° 510, p. 561-6. https://archive-ouverte.unige.ch/unige:98436