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Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l'évaluation de la balance bénéfice-risque

Fumeaux, Céline J Fischer
Bickle Graz, Myriam
Harari, Mathild Morisod
Epiney, Emmanuella
Tolsa, Cristina Borradori
Tolsa, Jean-François
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Published in Revue médicale suisse. 2016, vol. 12, no. 510, p. 561-6
Abstract Studies report that between 6 and 13% of women experience symptoms of depression during pregnancy and the postpartum period. The abundant data available make selective serotonin reuptake inhibitors (SSRIs) the first line treatment in pregnancy when a pharmacological treatment is required. Risks associated with the use of SSRIs during pregnancy are limited (moderate effect size) and are often not distinguishable from those inherent to the mother's disease. Yet, several questions regarding the SSRI safety profile for the unborn child are still under debate or require additional epidemiological data. The decision of SSRI use during pregnancy needs an individual evaluation of the risk-benefit balance.
Keywords Antidepressive Agents/adverse effects/therapeutic useDepressive Disorder/complications/drug therapyFemaleHumansPractice Patterns, Physicians'PregnancyPregnancy Complications/chemically induced/drug therapy/psychologyRisk AssessmentSerotonin Uptake Inhibitors/adverse effects/therapeutic use
PMID: 27149719
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WEISSKOPF, Etienne et al. Bon usage des antidépresseurs ISRS durant la grossesse – le défi de l'évaluation de la balance bénéfice-risque. In: Revue médicale suisse, 2016, vol. 12, n° 510, p. 561-6. https://archive-ouverte.unige.ch/unige:98436

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Deposited on : 2017-11-01

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